Publications by authors named "Marcella Petrone"

Claim this Profile
F
From In Vitro Efficacy to Long-Term HbA1c Response for GLP-1R/GlucagonR Agonism Using the 4GI-HbA1c Systems Model.
Rolien Bosch, Marcella Petrone, Rosalin Arends, Eric J G Sijbrands, Sven Hoefman

CPT Pharmacometrics Syst Pharmacol· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterisation of cotadutide's dual GLP-1/glucagon receptor agonistic effects on glycaemic control using an in vivo human glucose regulation quantitative systems pharmacology model.
Rolien Bosch, Marcella Petrone, Rosalin Arends, Paolo Vicini, Eric J G Sijbrands

Br J Pharmacol· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation.
Magnus T Dillon, Jeane Guevara, Kabir Mohammed, Emmanuel C Patin, Simon A Smith, Marcella Petrone

J Clin Invest· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacokinetics and Safety of Cotadutide, a GLP-1 and Glucagon Receptor Dual Agonist, in Individuals with Renal Impairment: A Single-Dose, Phase I, Bridging Study.
Gernot Klein, Marcella Petrone, Ye Yang, Thuong Hoang, Sheila Hazlett

Clin Pharmacokinet· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficacy and safety of cotadutide, a dual glucagon-like peptide-1 and glucagon receptor agonist, in a randomized phase 2a study of patients with type 2 diabetes and chronic kidney disease.
Victoria E R Parker, Thuong Hoang, Heike Schlichthaar, Fraser W Gibb, Barbara Wenzel, Marcella Petrone

Diabetes Obes Metab· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel integrated QSP model of in vivo human glucose regulation to support the development of a glucagon/GLP-1 dual agonist.
Rolien Bosch, Marcella Petrone, Rosalin Arends, Paolo Vicini, Eric J G Sijbrands

CPT Pharmacometrics Syst Pharmacol· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacokinetics, safety, tolerability and efficacy of cotadutide, a glucagon-like peptide-1 and glucagon receptor dual agonist, in phase 1 and 2 trials in overweight or obese participants of Asian descent with or without type 2 diabetes.
Michiko Asano, Akiko Sekikawa, Hyosung Kim, Robert A Gasser, Darren Robertson, Marcella Petrone

Diabetes Obes Metab· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficacy, Safety, and Mechanistic Insights of Cotadutide, a Dual Receptor Glucagon-Like Peptide-1 and Glucagon Agonist.
Victoria E R Parker, Darren Robertson, Tao Wang, David C Hornigold, Marcella Petrone

J Clin Endocrinol Metab· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Developing an injectable co-formulation of two antidiabetic drugs: Excipient impact on peptide aggregation and pharmacokinetic properties.
Anne-Laure Lainé, Sophie Houvenagel, Anders Broo, Ian Jones, Joanne Goodman, Marcella Petrone

Int J Pharm· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Darren J Schofield, Lorraine Irving, Laura Calo, Anna Bogstedt, Gareth Rees, Marcella Petrone

Neurobiol Dis· December 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Randomised, phase 1, dose-finding study of MEDI4166, a PCSK9 antibody and GLP-1 analogue fusion molecule, in overweight or obese patients with type 2 diabetes mellitus.
Meena Jain, Glenn Carlson, William Cook, Linda Morrow, Marcella Petrone

Diabetologia· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, Phase 1 study.
Philip D Ambery, Sebastian Klammt, Maximillian G Posch, Marcella Petrone, Wenji Pu

Br J Clin Pharmacol· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study.
Philip Ambery, Victoria E Parker, Michael Stumvoll, Maximilian G Posch, Tim Heise, Marcella Petrone

Lancet· June 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.
Robert A Comley, Cristian A Salinas, Mark Slifstein, Marcella Petrone, Carmine Marzano

J Pharmacol Exp Ther· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part 2: [g]-fused and hetero-fused systems.
Fabrizio Micheli, Giorgio Bonanomi, Simone Braggio, Anna Maria Capelli, Federica Damiani, Marcella Petrone

Bioorg Med Chem Lett· February 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part one: [h]-fused tricyclic systems.
Fabrizio Micheli, Giorgio Bonanomi, Simone Braggio, Anna Maria Capelli, Paolo Celestini, Marcella Petrone

Bioorg Med Chem Lett· February 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
1
1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists.
Fabrizio Micheli, Giorgio Bonanomi, Frank E Blaney, Simone Braggio, Anna Maria Capelli, Marcella Petrone

J Med Chem· October 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Isoindolone derivatives, a new class of 5-HT2C antagonists: synthesis and biological evaluation.
Dieter Hamprecht, Fabrizio Micheli, Giovanna Tedesco, Anna Checchia, Daniele Donati, Marcella Petrone

Bioorg Med Chem Lett· January 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
5
5-HT2C antagonists based on fused heterotricyclic templates: design, synthesis and biological evaluation.
Dieter Hamprecht, Fabrizio Micheli, Giovanna Tedesco, Daniele Donati, Marcella Petrone

Bioorg Med Chem Lett· January 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: synthesis and biological evaluation.
Fabrizio Micheli, Alessandra Pasquarello, Giovanna Tedesco, Dieter Hamprecht, Giorgio Bonanomi, Marcella Petrone

Bioorg Med Chem Lett· August 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of the role of intestinal and liver metabolism in the conversion of two different ester prodrugs of sanfetrinem to the parent drug in vitro and in vivo using different rat tissues and a surgically prepared rat model.
Simone Braggio, Alessia Ferrara, Matteo Sartori, Marco Bottacini, Ugo Zanelli, Marcella Petrone

Eur J Pharm Sci· July 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis