Publications by authors named "Marco Cavaco"

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Antimigratory and Antiproliferative Effects of the Brain-Targeted Peptide Conjugate PepH3-vCPP2319 on Triple Negative Breast Cancer Cell Cultures.
Catarina Gonçalves, Miguel A R B Castanho, Marco Cavaco, Vera Neves

J Pept Sci· August 2025

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PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier.
Anikó Szecskó, Mária Mészáros, Beatriz Simões, Marco Cavaco, Catarina Chaparro

Fluids Barriers CNS· April 2025

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The Potential of Peptide-Based Inhibitors in Disrupting Protein-Protein Interactions for Targeted Cancer Therapy.
Alexandra L Afonso, Catarina T Cavaleiro, Miguel A R B Castanho, Vera Neves, Marco Cavaco

Int J Mol Sci· March 2025

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vCPP2319 interacts with metastatic breast cancer extracellular vesicles (EVs) and transposes a human blood-brain barrier model.
Filipa D Oliveira, Marco Cavaco, Tiago N Figueira, Patrícia Napoleão, Javier Valle

Heliyon· December 2024

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Structural and Biochemical Characterization of Three Antimicrobial Peptides from Capsicum annuum L. var. annuum Leaves for Anti-Candida Use.
Milena Bellei Cherene, Gabriel Bonan Taveira, Fabricio Almeida-Silva, Marciele Souza da Silva, Marco Calvinho Cavaco

Probiotics Antimicrob Proteins· August 2024

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The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis.
Marco Cavaco, Clara Pérez-Peinado, Javier Valle, Ruben D M Silva, Lurdes Gano

Biomed Pharmacother· May 2024

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Molecular determinants for brain targeting by peptides: a meta-analysis approach with experimental validation.
Marco Cavaco, Patrícia Fraga, Javier Valle, Ruben D M Silva, Lurdes Gano

Fluids Barriers CNS· May 2024

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Quantitative Imaging of the Action of vCPP2319, an Antimicrobial Peptide from a Viral Scaffold, against Biofilms of a Clinical Isolate.
Susana A Dias, Sandra N Pinto, Ana S Silva-Herdade, Marco Cavaco, Vera Neves

ACS Infect Dis· October 2023

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Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells.
Antonio Zandona, Josip Madunić, Katarina Miš, Nikola Maraković, Pierre Dubois-Geoffroy, Marco Cavaco

Toxicology· August 2023

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Panobinostat-loaded folate targeted liposomes as a promising drug delivery system for treatment of canine B-cell lymphoma.
Ana S André, Joana N R Dias, Sandra I Aguiar, Ana Leonardo, Sara Nogueira, Marco Cavaco

Front Vet Sci· August 2023

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Rabbit derived VL single-domains as promising scaffolds to generate antibody-drug conjugates.
Ana S André, Joana N R Dias, Sandra Aguiar, Sara Nogueira, Pedro Bule, Marco Cavaco

Sci Rep· March 2023

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Selective Inhibition of Bruton's Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors.
Bárbara B Sousa, Cátia Rebelo de Almeida, Ana F Barahona, Raquel Lopes, Ana Martins-Logrado, Marco Cavaco

ACS Pharmacol Transl Sci· November 2022

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The antimetastatic breast cancer activity of the viral protein-derived peptide vCPP2319 as revealed by cellular biomechanics.
Filipa D Oliveira, Marco Cavaco, Tiago N Figueira, Javier Valle, Vera Neves

FEBS J· March 2022

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The Use of Antibody-Antibiotic Conjugates to Fight Bacterial Infections.
Marco Cavaco, Miguel A R B Castanho, Vera Neves

Front Microbiol· March 2022

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Targeting Zika Virus with New Brain- and Placenta-Crossing Peptide-Porphyrin Conjugates.
Toni Todorovski, Diogo A Mendonça, Lorena O Fernandes-Siqueira, Christine Cruz-Oliveira, Giuseppina Guida, Marco Cavaco

Pharmaceutics· March 2022

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Development of Breast Cancer Spheroids to Evaluate Cytotoxic Response to an Anticancer Peptide.
Marco Cavaco, Patrícia Fraga, Javier Valle, David Andreu, Miguel A R B Castanho

Pharmaceutics· November 2021

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Conjugation of a Blood Brain Barrier Peptide Shuttle to an Fc Domain for Brain Delivery of Therapeutic Biomolecules.
Marco Cavaco, Silvia Frutos, Paula Oliete, Javier Valle, David Andreu

ACS Med Chem Lett· November 2021

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Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening.
Sandra Isabel Aguiar, Joana N R Dias, Ana Santos André, Marta Lisete Silva, Diana Martins, Marco Cavaco

Pharmaceutics· October 2021

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Bioconjugate Supramolecular Pd Metallacages Penetrate the Blood Brain Barrier and .
Ben Woods, Rúben D M Silva, Claudia Schmidt, Darren Wragg, Marco Cavaco

Bioconjug Chem· July 2021

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Estimating peptide half-life in serum from tunable, sequence-related physicochemical properties.
Marco Cavaco, Javier Valle, Isabel Flores, David Andreu, Miguel A R B Castanho

Clin Transl Sci· July 2021

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Penetrating the Blood-Brain Barrier with New Peptide-Porphyrin Conjugates Having anti-HIV Activity.
Diogo A Mendonça, Mariët Bakker, Christine Cruz-Oliveira, Vera Neves, Maria Angeles Jiménez, Marco Cavaco

Bioconjug Chem· June 2021

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Orally Active Peptide Vector Allows Using Cannabis to Fight Pain While Avoiding Side Effects.
Maria Gallo, Estefanía Moreno, Sira Defaus, Antonio Ortega-Alvaro, Angel Gonzalez, Marco Cavaco

J Med Chem· May 2021

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The Challenge of Peptide Proteolytic Stability Studies: Scarce Data, Difficult Readability, and the Need for Harmonization.
Marco Cavaco, David Andreu, Miguel A R B Castanho

Angew Chem Int Ed Engl· January 2021

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PepH3, an Improved Peptide Shuttle for Receptor-independent Transport Across the Blood-Brain Barrier.
Marco Cavaco, Javier Valle, Ruben da Silva, João D G Correia, Miguel A R B Castanho

Curr Pharm Des· November 2020

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To What Extent Do Fluorophores Bias the Biological Activity of Peptides? A Practical Approach Using Membrane-Active Peptides as Models.
Marco Cavaco, Clara Pérez-Peinado, Javier Valle, Rúben D M Silva, João D G Correia

Front Bioeng Biotechnol· September 2020

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