Publications by authors named "Marco Inserra"

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NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype and epileptiform activity in a novel zebrafish model for Dravet Syndrome.
Wout J Weuring, Sakshi Singh, Linda Volkers, Martin B Rook, Ruben H van 't Slot, Marco Inserra

PLoS One· May 2021

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On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe.
Markus Muttenthaler, Simon T Nevin, Marco Inserra, Richard J Lewis, David J Adams

Aust J Chem· December 2019

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An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay.
Ralph J Stevenson, Iman Azimi, Jack U Flanagan, Marco Inserra, Irina Vetter

Bioorg Med Chem· July 2018

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Rapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional Bioassay.
Richard J Lewis, Marco Inserra, Irina Vetter, William C Holland, D Ransom Hardison

PLoS One· August 2017

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Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1.
Marco C Inserra, Mathilde R Israel, Ashlee Caldwell, Joel Castro, Jennifer R Deuis

Sci Rep· February 2017

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Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay.
Iman Azimi, Jack U Flanagan, Ralph J Stevenson, Marco Inserra, Irina Vetter

Bioorg Med Chem· January 2017

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Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
Sónia Troeira Henriques, Evelyne Deplazes, Nicole Lawrence, Olivier Cheneval, Stephanie Chaousis, Marco Inserra

J Biol Chem· August 2016

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Development of a μO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
Jennifer R Deuis, Zoltan Dekan, Marco C Inserra, Tzong-Hsien Lee, Marie-Isabel Aguilar

J Biol Chem· May 2016

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Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia.
Jennifer R Deuis, Ella Whately, Andreas Brust, Marco C Inserra, Naghmeh H Asvadi

ACS Chem Neurosci· October 2015

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δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails.
Ai-Hua Jin, Mathilde R Israel, Marco C Inserra, Jennifer J Smith, Richard J Lewis

Proc Biol Sci· July 2015

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α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.
Alexander Mueller, Hana Starobova, Marco C Inserra, Ai-Hua Jin, Jennifer R Deuis

Biochem Pharmacol· March 2015

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra

Nat Med· March 2015

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MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors.
Ai-Hua Jin, Irina Vetter, Sébastien Dutertre, Nikita Abraham, Nayara B Emidio, Marco Inserra

Biochemistry· January 2014

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Analgesic treatment of ciguatoxin-induced cold allodynia.
Katharina Zimmermann, Jennifer R Deuis, Marco C Inserra, Lindon S Collins, Barbara Namer

Pain· October 2013

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Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors.
Marco C Inserra, Shiva N Kompella, Irina Vetter, Andreas Brust, Norelle L Daly

Biochem Pharmacol· September 2013

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Venom Peptide modulators of the immune system.
Marco C Inserra, Richard J Lewis

Inflamm Allergy Drug Targets· October 2011

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