Publications by authors named "Simon T Nevin"

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On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe.
Markus Muttenthaler, Simon T Nevin, Marco Inserra, Richard J Lewis, David J Adams

Aust J Chem· December 2019

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Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors.
Gene Hopping, C-I Anderson Wang, Ron C Hogg, Simon T Nevin, Richard J Lewis

Biochem Pharmacol· October 2014

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Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding.
Aline Dantas de Araujo, Brid Callaghan, Simon T Nevin, Norelle L Daly, David J Craik

Angew Chem Int Ed Engl· July 2011

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Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels.
Norelle L Daly, Brid Callaghan, Richard J Clark, Simon T Nevin, David J Adams

J Biol Chem· March 2011

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Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization.
Erica S Lovelace, Sunithi Gunasekera, Charlotta Alvarmo, Richard J Clark, Simon T Nevin

Antioxid Redox Signal· January 2011

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The engineering of an orally active conotoxin for the treatment of neuropathic pain.
Richard J Clark, Jonas Jensen, Simon T Nevin, Brid P Callaghan, David J Adams

Angew Chem Int Ed Engl· September 2010

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Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.
Markus Muttenthaler, Simon T Nevin, Anton A Grishin, Shyuan T Ngo, Peng T Choy

J Am Chem Soc· March 2010

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Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor.
Reena Halai, Richard J Clark, Simon T Nevin, Jonas E Jensen, David J Adams

J Biol Chem· July 2009

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Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues.
Emma L Millard, Simon T Nevin, Marion L Loughnan, Annette Nicke, Richard J Clark

J Biol Chem· February 2009

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Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function.
Andre L Samson, Simon T Nevin, David Croucher, Be'eri Niego, Philip B Daniel

J Neurochem· November 2008

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Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function.
Ai-Hua Jin, Norelle L Daly, Simon T Nevin, Ching-I A Wang, Sebastien Dutertre

J Med Chem· September 2008

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The three-dimensional structure of the analgesic alpha-conotoxin, RgIA.
Richard J Clark, Norelle L Daly, Reena Halai, Simon T Nevin, David J Adams

FEBS Lett· March 2008

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Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics.
Ai-Hua Jin, Hemma Brandstaetter, Simon T Nevin, Chia Chia Tan, Richard J Clark

BMC Struct Biol· April 2007

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The synthesis, structural characterization, and receptor specificity of the alpha-conotoxin Vc1.1.
Richard J Clark, Harald Fischer, Simon T Nevin, David J Adams, David J Craik

J Biol Chem· August 2006

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Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum.
Marion Loughnan, Annette Nicke, Alun Jones, Christina I Schroeder, Simon T Nevin

J Biol Chem· August 2006

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Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.
Christopher J Armishaw, Norelle L Daly, Simon T Nevin, David J Adams, David J Craik

J Biol Chem· May 2006

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Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.
Richard J Clark, Harald Fischer, Louise Dempster, Norelle L Daly, K Johan Rosengren, Simon T Nevin

Proc Natl Acad Sci U S A· September 2005

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Insights into the structural basis for zinc inhibition of the glycine receptor.
Simon T Nevin, Brett A Cromer, Justine L Haddrill, Craig J Morton, Michael W Parker

J Biol Chem· August 2003

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Asymmetric contribution of alpha and beta subunits to the activation of alphabeta heteromeric glycine receptors.
Qiang Shan, Simon T Nevin, Justine L Haddrill, Joseph W Lynch

J Neurochem· July 2003

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