Publications by authors named "Reena Halai"

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PET-MRI biomarkers reveal efficacy of a novel NLRP3 inhibitor in Parkinson's disease models.
Eduardo A Albornoz, Karine Mardon, Rajiv Bhalla, Vinod Kumar, Damion H R Stimson, Reena Halai

Brain· October 2025

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Novel Macrocyclic NLRP3 Inhibitors.
Stefanie Mesch, Jonathan Shannon, David Miller, Angus MacLeod, Léa Bouché, Reena Halai

J Med Chem· December 2024

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Pharmacological Inhibition of the Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome with MCC950.
Sarah E Corcoran, Reena Halai, Matthew A Cooper

Pharmacol Rev· July 2021

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Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling.
Zoe V Schofield, Daniel Croker, Avril A B Robertson, Nicholas L Massey, Chantal Donovan, Reena Halai

Sci Rep· December 2018

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Common genetic variation drives molecular heterogeneity in human iPSCs.
Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Reena Halai

Nature· June 2017

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Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.
Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Reena Halai

Nature· June 2017

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Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.
Daniel E Croker, Peter N Monk, Reena Halai, Geraldine Kaeslin, Zoe Schofield

Immunol Cell Biol· September 2016

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Derivation of ligands for the complement C3a receptor from the C-terminus of C5a.
Reena Halai, Meghan L Bellows-Peterson, Will Branchett, James Smadbeck, Chris A Kieslich

Eur J Pharmacol· December 2014

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Glycopeptide antibiotics: back to the future.
Mark S Butler, Karl A Hansford, Mark A T Blaskovich, Reena Halai, Matthew A Cooper

J Antibiot (Tokyo)· September 2014

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C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.
Daniel E Croker, Reena Halai, Geraldine Kaeslin, Elisabeth Wende, Beate Fehlhaber

Immunol Cell Biol· August 2014

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C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.
Daniel E Croker, Reena Halai, David P Fairlie, Matthew A Cooper

Immunol Cell Biol· July 2014

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Neutrophils--a key component of ischemia-reperfusion injury.
Zoe Victoria Schofield, Trent Martin Woodruff, Reena Halai, Mike Chia-Lun Wu, Matthew Allister Cooper

Shock· December 2013

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A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.
Reena Halai, Daniel E Croker, Jacky Y Suen, David P Fairlie, Matthew A Cooper

Biosensors (Basel)· July 2012

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Using label-free screening technology to improve efficiency in drug discovery.
Reena Halai, Matthew A Cooper

Expert Opin Drug Discov· February 2012

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Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.
Reena Halai, Brid Callaghan, Norelle L Daly, Richard J Clark, David J Adams

J Med Chem· October 2011

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Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor.
Reena Halai, Richard J Clark, Simon T Nevin, Jonas E Jensen, David J Adams

J Biol Chem· July 2009

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Conotoxins: natural product drug leads.
Reena Halai, David J Craik

Nat Prod Rep· April 2009

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The three-dimensional structure of the analgesic alpha-conotoxin, RgIA.
Richard J Clark, Norelle L Daly, Reena Halai, Simon T Nevin, David J Adams

FEBS Lett· March 2008

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ConoServer, a database for conopeptide sequences and structures.
Quentin Kaas, Jan-C Westermann, Reena Halai, Conan K L Wang, David J Craik

Bioinformatics· February 2008

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