Publications by authors named "Marcos Lorca"

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Benzo[]imidazole-Naphthalen-Arylmethanone Regioisomers as CB Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach.
Analia Young Hwa Cho, Renato Burgos Ravanal, Valeria Zuñiga Salazar, Marco Mellado, Marcos Lorca

Int J Mol Sci· October 2025

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Design of Hybrid Quinoline-Chalcone Compounds Against Based on Computational Techniques: 2D- and 3D-QSAR with Experimental Validation.
Marcos Lorca, Gisela C Muscia, Jaime Mella, Luciana Thomaz, Jenicer K Yokoyama-Yasunaka

Pharmaceuticals (Basel)· October 2025

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Structure-Guided Discovery of Benzoic-Acid-Based TRPC6 Ligands: An Integrated Docking, MD, and MM-GBSA SAR Study: Potential Therapeutic Molecules for Autism Spectrum Disorder.
Nicolás Ignacio Silva, Gianfranco Sabadini, David Cabezas, Cristofer González, Paulina González, Marcos Lorca

Pharmaceuticals (Basel)· October 2025

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Past and Present of the Antioxidant Studies in Chile: A Bibliometric Study from 2000 to 2024.
Marcos Lorca, Alejandro Vega-Muñoz, Alison Acosta, David Cabezas, Katy Díaz

Antioxidants (Basel)· August 2025

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2D/3D-QSAR Model Development Based on a Quinoline Pharmacophoric Core for the Inhibition of : An In Silico Approach with Experimental Validation.
Marcos Lorca, Gisela C Muscia, Susana Pérez-Benavente, José M Bautista, Alison Acosta

Pharmaceuticals (Basel)· July 2024

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Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives.
Marcos Lorca, David Cabezas, Ileana Araque, Andrés Terán, Santiago Hernández

Steroids· February 2023

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Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Julio Rodríguez-Lavado, Carlos Gallardo-Garrido, Michael Mallea, Victor Bustos, Rodrigo Osorio, Marcos Lorca

Eur J Med Chem· July 2020

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New Morphiceptin Peptidomimetic Incorporating (1,2,3,4,5)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic acid: Synthesis and Structural Study.
Raquel Soengas, Marcos Lorca, Begoña Pampín, Víctor M Sánchez-Pedregal, Ramón J Estévez

Molecules· June 2020

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Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands.
Marcos Lorca, Yudisladys Valdes, Hery Chung, Javier Romero-Parra, C David Pessoa-Mahana

Int J Mol Sci· May 2019

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Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles.
Marcos Lorca, Cesar Morales-Verdejo, David Vásquez-Velásquez, Juan Andrades-Lagos, Javier Campanini-Salinas

Molecules· May 2018

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Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.
Javier Romero-Parra, Hery Chung, Ricardo A Tapia, Mario Faúndez, Cesar Morales-Verdejo, Marcos Lorca

Eur J Pharm Sci· April 2017

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