Publications by authors named "Marcus Gerlach"

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TUB-040, a Homogeneous and Hydrophilic NaPi2b-Targeting ADC with Stably Linked Exatecan, Exhibits Long-lasting Antitumor Activity and a Well-Tolerated Safety Profile.
Annette M Vogl, Saskia Schmitt, Isabelle Mai, Paul Machui, Sarah Herterich, Marcus Gerlach

Mol Cancer Ther· November 2025

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TUB-010, a novel anti-CD30 antibody-drug conjugate based on Tub-tag technology, widens the therapeutic window by reducing toxicity while maintaining high efficacy.
Marcus Gerlach, Saskia Schmitt, Philipp Cyprys, Marc-André Kasper, Isabelle Mai

Mol Cancer Ther· August 2025

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Orthogonal Site-Specific Dual Bioconjugation of Aryl and Alkyl Thiols.
Mark A R de Geus, Christian E Stieger, Jan Vincent V Arafiles, Jean-Romain P J Lotthé, Peter Schmieder, Marcus Gerlach

J Am Chem Soc· June 2025

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Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody-Drug Conjugates.
Saskia Schmitt, Paul Machui, Isabelle Mai, Sarah Herterich, Swetlana Wunder, Marcus Gerlach

Mol Cancer Ther· February 2024

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Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML.
Maike Roas, Binje Vick, Marc-André Kasper, Marina Able, Harald Polzer, Marcus Gerlach

Blood· March 2023

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Site-Specific Conjugation Strategy for Dual Antibody-Drug Conjugates Using Aerobic Formylglycine-Generating Enzymes.
Mareile Boschanski, Tobias Krüger, Lennard Karsten, Georg Falck, Sarfaraz Alam, Marcus Gerlach

Bioconjug Chem· June 2021

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Site-Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy.
Jonathan Schwach, Ksenia Kolobynina, Katharina Brandstetter, Marcus Gerlach, Philipp Ochtrop

Chembiochem· April 2021

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Tubulin Tyrosine Ligase-Mediated Modification of Proteins.
Marcus Gerlach, Tina Stoschek, Heinrich Leonhardt, Christian P R Hackenberger, Dominik Schumacher

Methods Mol Biol· March 2020

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N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates.
Marc-André Kasper, Marcus Gerlach, Anselm F L Schneider, Christiane Groneberg, Philipp Ochtrop

Chembiochem· January 2020

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Ethynylphosphonamidates for the Rapid and Cysteine-Selective Generation of Efficacious Antibody-Drug Conjugates.
Marc-André Kasper, Andreas Stengl, Philipp Ochtrop, Marcus Gerlach, Tina Stoschek

Angew Chem Int Ed Engl· August 2019

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TuPPL: Tub-tag mediated C-terminal protein-protein-ligation using complementary click-chemistry handles.
Andreas Stengl, Marcus Gerlach, Marc-André Kasper, Christian P R Hackenberger, Heinrich Leonhardt

Org Biomol Chem· May 2019

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Two-fold Bioorthogonal Derivatization by Different Formylglycine-Generating Enzymes.
Tobias Krüger, Stefanie Weiland, Georg Falck, Marcus Gerlach, Mareile Boschanski

Angew Chem Int Ed Engl· June 2018

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