Publications by authors named "Marek Mraz"

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FoxO1 signaling in B cell malignancies and its therapeutic targeting.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz

FEBS Lett· October 2025

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Establishment of Coala: a novel 3D and 2D cancer cell line derived from colorectal cancer liver metastasis.
Sandra Mersakova, Juraj Marcinek, Dusan Brany, Olga Chodelkova, Martin Vorcak, Marek Mraz

Hum Cell· August 2025

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FoxO1/Rictor axis induces a nongenetic adaptation to ibrutinib via Akt activation in chronic lymphocytic leukemia.
Laura Ondrisova, Vaclav Seda, Krystof Hlavac, Petra Pavelkova, Eva Hoferkova, Marek Mraz

J Clin Invest· October 2024

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Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs.
Eva Hoferkova, Vaclav Seda, Sona Kadakova, Jan Verner, Tomas Loja, Marek Mraz

Leukemia· August 2024

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Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities.
Rahul Deb, Marcelo D T Torres, Miroslav Boudný, Markéta Koběrská, Floriana Cappiello

J Med Chem· August 2024

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Blockage of BCL-XL overcomes venetoclax resistance across BCL2+ lymphoid malignancies irrespective of BIM status.
Alexandra Dolnikova, Dmitry Kazantsev, Magdalena Klanova, Eva Pokorna, Dana Sovilj, Marek Mraz

Blood Adv· July 2024

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5'-UTR mRNA splicing determines CD20 levels.
Marek Mraz

Blood· November 2023

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MicroRNA Profiling of Self-Renewing Human Neural Stem Cells Reveals Novel Sets of Differentially Expressed microRNAs During Neural Differentiation In Vitro.
Veronika Fedorova, Katerina Amruz Cerna, Jan Oppelt, Veronika Pospisilova, Tomas Barta, Marek Mraz

Stem Cell Rev Rep· July 2023

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High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in patients with CLL.
Giorgia Chiodin, Samantha Drennan, Enrica A Martino, Laura Ondrisova, Isla Henderson, Marek Mraz

Blood Adv· September 2022

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Genetic mechanism for the loss of PRAME in B cell lymphomas.
Marek Mraz

J Clin Invest· July 2022

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In Vitro and In Vivo Models of CLL-T Cell Interactions: Implications for Drug Testing.
Eva Hoferkova, Sona Kadakova, Marek Mraz

Cancers (Basel)· June 2022

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Synthesis and Profiling of Highly Selective Inhibitors of Methyltransferase DOT1L Based on Carbocyclic C-Nucleosides.
Prashant Khirsariya, Patrik Pospíšil, Lukáš Maier, Miroslav Boudný, Martin Babáš

J Med Chem· April 2022

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Rituximab induces rapid blood repopulation by CLL cells mediated through their release from immune niches and complement exhaustion.
Marek Borsky, Viera Hrabcakova, Jitka Novotna, Yvona Brychtova, Michael Doubek, Marek Mraz

Leuk Res· December 2021

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IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3Kδ inhibitor idelalisib.
Veronika Sandova, Gabriela Mladonicka Pavlasova, Vaclav Seda, Katerina Amruz Cerna, Sonali Sharma, Marek Mraz

Haematologica· November 2021

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FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.
Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Marek Mraz

Blood· September 2021

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LncRNAs in adaptive immunity: role in physiological and pathological conditions.
Pedro Faria Zeni, Marek Mraz

RNA Biol· May 2021

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miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors.
Sonali Sharma, Gabriela Mladonicka Pavlasova, Vaclav Seda, Katerina Amruz Cerna, Eva Vojackova, Marek Mraz

Blood· May 2021

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STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma.
Cosimo Lobello, Boris Tichy, Vojtech Bystry, Lenka Radova, Daniel Filip, Marek Mraz

Leukemia· May 2021

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Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies.
Laura Ondrisova, Marek Mraz

Front Oncol· October 2020

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The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy.
Gabriela Pavlasova, Marek Mraz

Haematologica· June 2020

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The role of MYC in the transformation and aggressiveness of 'indolent' B-cell malignancies.
Daniel Filip, Marek Mraz

Leuk Lymphoma· March 2020

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Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.
Miroslav Boudny, Jana Zemanova, Prashant Khirsariya, Marek Borsky, Jan Verner, Marek Mraz

Haematologica· December 2019

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Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts.
Lucie Peskova, Katerina Cerna, Jan Oppelt, Marek Mraz, Tomas Barta

Sci Rep· October 2019

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Detection of a deletion at 22q11 locus involving ZNF280A/ZNF280B/PRAME/GGTLC2 in B-cell malignancies: simply a consequence of an immunoglobulin lambda light chain rearrangement.
Marek Mraz, Sarka Pospisilova

Br J Haematol· August 2019

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Impact of gene mutations and chromosomal aberrations on progression-free survival in chronic lymphocytic leukemia patients treated with front-line chemoimmunotherapy: Clinical practice experience.
Michaela Spunarova, Nikola Tom, Sarka Pavlova, Marek Mraz, Yvona Brychtova

Leuk Res· June 2019

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