Publications by authors named "Margaret MacLean"

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Cytochrome P450 1A1 influences obesity-induced pulmonary hypertension.
Joshua P Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Margaret R MacLean

Br J Pharmacol· November 2025

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Epicardial Adipose Tissue as an Independent Risk Factor for Mortality in Pulmonary Arterial Hypertension.
Breanne E McCarthy, Rui Feng, Drew A Torigian, Yubing Tong, Jason S Fritz, Margaret R MacLean

Chest· May 2025

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Ang-(1-7) and ET-1 Interplay Through Mas and ET Receptor Interaction Defines a Novel Vasoprotective Mechanism.
Augusto C Montezano, Jithin Kuriakose, Katie Y Hood, Yuan Yan Sin, Livia L Camargo, Margaret R MacLean

Hypertension· February 2025

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Pulmonary Hypertension and Anastrozole (PHANTOM): A Randomized, Double-Blind, Placebo-Controlled Trial.
Steven M Kawut, Rui Feng, Susan S Ellenberg, Roham Zamanian, Todd Bull, Margaret MacLean

Am J Respir Crit Care Med· November 2024

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Pulmonary arterial hypertension: Sex matters.
Joshua P Dignam, Smriti Sharma, Ioannis Stasinopoulos, Margaret R MacLean

Br J Pharmacol· April 2024

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Notch3/Hes5 Induces Vascular Dysfunction in Hypoxia-Induced Pulmonary Hypertension Through ER Stress and Redox-Sensitive Pathways.
Hannah E Morris, Karla B Neves, Margaret Nilsen, Augusto C Montezano, Margaret R MacLean

Hypertension· August 2023

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Serotonin and Pulmonary Hypertension; Sex and Drugs and ROCK and Rho.
Margaret R MacLean, Barry Fanburg, Nicolas Hill, Howard M Lazarus, Thomas F Pack

Compr Physiol· August 2022

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A pilot study to examine association of BMI with functional class and 6 min walk distance in idiopathic and heritable PAH: Possible association with estrogen metabolism.
Margaret R MacLean, Divya Pandya, Emilia M Swietlik, Nina Denver, Kirsty Mair

Pulm Circ· July 2022

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Sex-dependent right ventricular hypertrophic gene changes after methamphetamine treatment in mice.
Hicham Labazi, Margaret Nilsen, Margaret R MacLean

Eur J Pharmacol· June 2021

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Sex Differences in Pulmonary Hypertension.
Hannah Morris, Nina Denver, Rosemary Gaw, Hicham Labazi, Kirsty Mair, Margaret R MacLean

Clin Chest Med· March 2021

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Estrogen Signaling and Portopulmonary Hypertension: The Pulmonary Vascular Complications of Liver Disease Study (PVCLD2).
Nadine Al-Naamani, Michael J Krowka, Kimberly A Forde, Karen L Krok, Rui Feng, Margaret R MacLean

Hepatology· February 2021

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Insights from the Menstrual Cycle in Pulmonary Arterial Hypertension.
Grayson L Baird, Thomas Walsh, Jason Aliotta, Melissa Allahua, Ruth Andrew, Margaret R MacLean

Ann Am Thorac Soc· February 2021

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Direct Delivery of MicroRNA96 to the Lungs Reduces Progression of Sugen/Hypoxia-Induced Pulmonary Hypertension in the Rat.
Craig K Docherty, Nina Denver, Simon Fisher, Margaret Nilsen, Dianne Hillyard, Margaret R MacLean

Mol Ther Nucleic Acids· December 2020

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Melatonin: shining some light on pulmonary hypertension.
Margaret R MacLean

Cardiovasc Res· November 2020

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Sex-Dependent Changes in Right Ventricular Gene Expression in Response to Pressure Overload in a Rat Model of Pulmonary Trunk Banding.
Hicham Labazi, Julie Birkmose Axelsen, Dianne Hillyard, Margaret Nilsen, Asger Andersen, Margaret R MacLean

Biomedicines· October 2020

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Obesity, estrogens and adipose tissue dysfunction - implications for pulmonary arterial hypertension.
Kirsty M Mair, Rosemary Gaw, Margaret R MacLean

Pulm Circ· September 2020

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Reduction of the serotonin 5-HT and 5-HT receptor-mediated contraction of human pulmonary artery by the combined 5-HT receptor antagonist and serotonin transporter inhibitor LY393558.
Marta Baranowska-Kuczko, Hanna Kozłowska, Eberhard Schlicker, Manfred Göthert, Margaret R MacLean

Pharmacol Rep· June 2020

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Apoptosis signal-regulating kinase 1 inhibition in and models of pulmonary hypertension.
Kathryn S Wilson, Hanna Buist, Kornelija Suveizdyte, John T Liles, Grant R Budas, Margaret R MacLean

Pulm Circ· May 2020

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Estrogen metabolites in a small cohort of patients with idiopathic pulmonary arterial hypertension.
Nina Denver, Natalie Z M Homer, Ruth Andrew, Katie Y Harvey, Nicholas Morrell, Margaret R MacLean

Pulm Circ· March 2020

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Notch3 signalling and vascular remodelling in pulmonary arterial hypertension.
Hannah E Morris, Karla B Neves, Augusto C Montezano, Margaret R MacLean, Rhian M Touyz

Clin Sci (Lond)· December 2019

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Fulvestrant for the Treatment of Pulmonary Arterial Hypertension.
Steven M Kawut, Diane Pinder, Nadine Al-Naamani, Amber McCormick, Harold I Palevsky, Margaret R MacLean

Ann Am Thorac Soc· November 2019

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Current strategies for quantification of estrogens in clinical research.
Nina Denver, Shazia Khan, Natalie Z M Homer, Margaret R MacLean, Ruth Andrew

J Steroid Biochem Mol Biol· September 2019

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Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension.
Kirsty M Mair, Katie Y Harvey, Alasdair D Henry, Dianne Z Hillyard, Margaret Nilsen, Margaret R MacLean

Eur Respir J· June 2019

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Data for analysis of catechol estrogen metabolites in human plasma by liquid chromatography tandem mass spectrometry.
Nina Denver, Shazia Khan, Ioannis Stasinopoulos, Colin Church, Natalie Z M Homer, Margaret R MacLean

Data Brief· April 2019

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Influence of 2-Methoxyestradiol and Sex on Hypoxia-Induced Pulmonary Hypertension and Hypoxia-Inducible Factor-1-α.
Craig K Docherty, Margaret Nilsen, Margaret R MacLean

J Am Heart Assoc· March 2019

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