Publications by authors named "Maria Bretner"

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Synthesis of Novel Acyl Derivatives of 3-(4,5,6,7-Tetrabromo-1-benzimidazol-1-yl)propan-1-ols-Intracellular TBBi-Based CK2 Inhibitors with Proapoptotic Properties.
Konrad Chojnacki, Patrycja Wińska, Olena Karatsai, Mirosława Koronkiewicz, Małgorzata Milner-Krawczyk, Maria Bretner

Int J Mol Sci· June 2021

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Formylation of a metathesis-derived [4]-ferrocene: a simple route to anticancer organometallics.
Maria Mazur, Michał Mrozowicz, Włodzimierz Buchowicz, Mariola Koszytkowska-Stawińska, Radosław Kamiński, Maria Bretner

Dalton Trans· August 2020

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New insight into nucleo α-amino acids - Synthesis and SAR studies on cytotoxic activity of β-pyrimidine alanines.
Jolanta Ignatowska, Ewa Mironiuk-Puchalska, Piotr Grześkowiak, Patrycja Wińska, Monika Wielechowska, Maria Bretner

Bioorg Chem· July 2020

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A competition between hydrophobic and electrostatic interactions in protein-ligand systems. Binding of heterogeneously halogenated benzotriazoles by the catalytic subunit of human protein kinase CK2.
Sławomir Kasperowicz, Ewa Marzec, Agnieszka M Maciejewska, Damian Trzybiński, Maria Bretner

IUBMB Life· June 2020

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Simultaneous Inhibition of Protein Kinase CK2 and Dihydrofolate Reductase Results in Synergistic Effect on Acute Lymphoblastic Leukemia Cells.
Patrycja Wińska, Łukasz Widło, Katarzyna Skierka, Alicja Krzyśko, Mirosława Koronkiewicz, Maria Bretner

Anticancer Res· July 2019

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Human dihydrofolate reductase is a substrate of protein kinase CK2α.
Katarzyna Skierka, Paweł Wilamowski, Monika Wielechowska, Dominik Cysewski, Elżbieta Senkara, Maria Bretner

Biochem Biophys Res Commun· May 2019

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Potential bioisosteres of β-uracilalanines derived from 1H-1,2,3-triazole-C-carboxylic acids.
Ewa Mironiuk-Puchalska, Włodzimierz Buchowicz, Piotr Grześkowiak, Patrycja Wińska, Monika Wielechowska, Maria Bretner

Bioorg Chem· March 2019

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Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α' Structures.
Dirk Lindenblatt, Anna Nickelsen, Violetta M Applegate, Jennifer Hochscherf, Benedict Witulski, Maria Bretner

ACS Omega· March 2019

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Effect of Simultaneous Inhibition of Protein Kinase CK2 and Thymidylate Synthase in Leukemia and Breast Cancer Cells.
Patrycja Wińska, Katarzyna Skierka, Edyta Łukowska-Chojnacka, Mirosława Koronkiewicz, Joanna Cieśla, Maria Bretner

Anticancer Res· August 2018

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Synthesis of novel proxyphylline derivatives with dual Anti-Candida albicans and anticancer activity.
Paweł Borowiecki, Patrycja Wińska, Maria Bretner, Małgorzata Gizińska, Mirosława Koronkiewicz

Eur J Med Chem· April 2018

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Synthesis, in vitro antiproliferative activity and kinase profile of new benzimidazole and benzotriazole derivatives.
Konrad Chojnacki, Patrycja Wińska, Katarzyna Skierka, Monika Wielechowska, Maria Bretner

Bioorg Chem· June 2017

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Synthesis of polybrominated benzimidazole and benzotriazole derivatives containing a tetrazole ring and their cytotoxic activity.
Edyta Łukowska-Chojnacka, Patrycja Wińska, Monika Wielechowska, Maria Bretner

Monatsh Chem· June 2016

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Lipase-Catalyzed Kinetic Resolution of Novel Antifungal N-Substituted Benzimidazole Derivatives.
Edyta Łukowska-Chojnacka, Monika Staniszewska, Małgorzata Bondaryk, Jan K Maurin, Maria Bretner

Chirality· April 2016

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[The specific enzyme inhibitors for potential therapeutic use].
Maria Bretner

Postepy Biochem· March 2016

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A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cells.
Kamil Krol, Izabela Brozda, Marek Skoneczny, Maria Bretner, Adrianna Skoneczna

PLoS One· February 2016

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Synthesis of novel polybrominated benzimidazole derivatives-potential CK2 inhibitors with anticancer and proapoptotic activity.
Edyta Łukowska-Chojnacka, Patrycja Wińska, Monika Wielechowska, Martyna Poprzeczko, Maria Bretner

Bioorg Med Chem· February 2016

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Thermodynamic parameters for binding of some halogenated inhibitors of human protein kinase CK2.
Maria Winiewska, Małgorzata Makowska, Piotr Maj, Monika Wielechowska, Maria Bretner

Biochem Biophys Res Commun· January 2015

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Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties.
Paweł Borowiecki, Adam M Wawro, Patrycja Wińska, Monika Wielechowska, Maria Bretner

Eur J Med Chem· September 2014

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Synthesis and in vitro antibacterial activity of 5-halogenomethylsulfonyl- benzimidazole and benzotriazole derivatives.
Zbigniew Ochal, Maria Bretner, Renata Wolinowska, Stefan Tyski

Med Chem· December 2013

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Chemical proteomics and functional proteomics strategies for protein kinase inhibitor validation and protein kinase substrate identification: applications to protein kinase CK2.
Laszlo Gyenis, Jacob P Turowec, Maria Bretner, David W Litchfield

Biochim Biophys Acta· July 2013

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Functional proteomics strategy for validation of protein kinase inhibitors reveals new targets for a TBB-derived inhibitor of protein kinase CK2.
Laszlo Gyenis, Agnieszka Kuś, Maria Bretner, David W Litchfield

J Proteomics· April 2013

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Unbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of EEF1D as a substrate for CK2.
Laszlo Gyenis, James S Duncan, Jacob P Turowec, Maria Bretner, David W Litchfield

J Proteome Res· November 2011

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Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α'.
Nils Bischoff, Jennifer Raaf, Birgitte Olsen, Maria Bretner, Olaf-Georg Issinger

Mol Cell Biochem· October 2011

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Design and synthesis of CK2 inhibitors.
Małgorzata Makowska, Edyta Łukowska-Chojnacka, Patrycja Wińska, Agnieszka Kuś, Aleksandra Bilińska-Chomik, Maria Bretner

Mol Cell Biochem· October 2011

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Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation.
Damian Graczyk, Janusz Debski, Grazyna Muszyńska, Maria Bretner, Olivier Lefebvre

Proc Natl Acad Sci U S A· March 2011

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