Publications by authors named "Olaf-Georg Issinger"

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Phytochemicals in cancer and their effect on the PI3K/AKT-mediated cellular signalling.
Olaf-Georg Issinger, Barbara Guerra

Biomed Pharmacother· July 2021

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Role of Protein Kinase CK2 in Aberrant Lipid Metabolism in Cancer.
Barbara Guerra, Olaf-Georg Issinger

Pharmaceuticals (Basel)· October 2020

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Delivery of proteins encapsulated in chitosan-tripolyphosphate nanoparticles to human skin melanoma cells.
Mai Bay Stie, Henrik Seir Thoke, Olaf-Georg Issinger, Jennifer Hochscherf, Barbara Guerra

Colloids Surf B Biointerfaces· February 2019

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Natural Compounds and Derivatives as Ser/Thr Protein Kinase Modulators and Inhibitors.
Barbara Guerra, Olaf-Georg Issinger

Pharmaceuticals (Basel)· January 2019

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Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma.
Maj Rabjerg, Barbara Guerra, Aida Oliván-Viguera, Minne Line Nedergaard Mikkelsen, Ralf Köhler, Olaf-Georg Issinger

Oncotarget· January 2017

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Acetoxymethyl Ester of Tetrabromobenzimidazole-Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells.
Kaido Viht, Siiri Saaver, Jürgen Vahter, Erki Enkvist, Darja Lavogina, Olaf-Georg Issinger

Bioconjug Chem· December 2015

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The kinase inhibitor D11 induces caspase-mediated cell death in cancer cells resistant to chemotherapeutic treatment.
Barbara Guerra, Mette Fischer, Susanne Schaefer, Olaf-Georg Issinger

J Exp Clin Cancer Res· October 2015

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Identification of a novel potent, selective and cell permeable inhibitor of protein kinase CK2 from the NIH/NCI Diversity Set Library.
Barbara Guerra, Jennifer Hochscherf, Nina Bjelkerup Jensen, Olaf-Georg Issinger

Mol Cell Biochem· August 2015

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A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures.
Barbara Guerra, Nils Bischoff, Volodymyr G Bdzhola, Sergiy M Yarmoluk, Olaf-Georg Issinger

ACS Chem Biol· July 2015

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Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2α/CK2β interaction.
Jennifer Hochscherf, Dirk Lindenblatt, Michaela Steinkrüger, Eungyoung Yoo, Özlem Ulucan, Olaf-Georg Issinger

Anal Biochem· January 2015

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Protein kinase CK2 inhibition is associated with the destabilization of HIF-1α in human cancer cells.
Barbara Guerra, Tine D L Rasmussen, Alexander Schnitzler, Hans H Jensen, Brigitte S Boldyreff, Olaf-Georg Issinger

Cancer Lett· January 2015

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Evidence for aggregation of protein kinase CK2 in the cell: a novel strategy for studying CK2 holoenzyme interaction by BRET(2).
Gerda M Hübner, Jane Nøhr Larsen, Barbara Guerra, Karsten Niefind, Milka Vrecl, Olaf-Georg Issinger

Mol Cell Biochem· December 2014

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Cytotoxic effects exerted by pentachlorophenol by targeting nodal pro-survival signaling pathways in human pancreatic cancer cells.
Susanne Schaefer, Jan N Kreutzer, Olaf-Georg Issinger, Barbara Guerra

Toxicol Rep· November 2014

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The Yin and Yang of redox regulation.
Lars Folke Olsen, Olaf-Georg Issinger, Barbara Guerra

Redox Rep· May 2014

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The protein kinase CK2(Andante) holoenzyme structure supports proposed models of autoregulation and trans-autophosphorylation.
Alexander Schnitzler, Birgitte Brinkmann Olsen, Olaf-Georg Issinger, Karsten Niefind

J Mol Biol· May 2014

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Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs.
Barbara Guerra, Kuniyoshi Iwabuchi, Olaf-Georg Issinger

Cancer Lett· April 2014

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Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases.
Ramesh Ekambaram, Erki Enkvist, Ganesh babu Manoharan, Mihkel Ugandi, Marje Kasari, Olaf-Georg Issinger

Chem Commun (Camb)· April 2014

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Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity.
Virginia Spanò, Alessandra Montalbano, Anna Carbone, Barbara Parrino, Patrizia Diana, Olaf-Georg Issinger

Eur J Med Chem· March 2014

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ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.
John W Scott, Jonathan S Oakhill, Naomi X Y Ling, Christopher G Langendorf, Richard C Foitzik, Olaf-Georg Issinger

Biochem Biophys Res Commun· January 2014

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First structure of protein kinase CK2 catalytic subunit with an effective CK2β-competitive ligand.
Jennifer Raaf, Barbara Guerra, Ines Neundorf, Bertan Bopp, Olaf-Georg Issinger

ACS Chem Biol· May 2013

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A subnanomolar fluorescent probe for protein kinase CK2 interaction studies.
Erki Enkvist, Kaido Viht, Nils Bischoff, Jürgen Vahter, Siiri Saaver, Olaf-Georg Issinger

Org Biomol Chem· November 2012

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Low-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing bias.
Karsten Klopffleisch, Olaf-Georg Issinger, Karsten Niefind

Acta Crystallogr D Biol Crystallogr· August 2012

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2-Triazenoazaindoles: α novel class of triazenes inducing transcriptional down-regulation of EGFR and HER-2 in human pancreatic cancer cells.
Jan N Kreutzer, Alessia Salvador, Patrizia Diana, Girolamo Cirrincione, Daniela Vedaldi, Olaf-Georg Issinger

Int J Oncol· April 2012

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Comparative analysis of stress responses of H9c2 rat cardiomyoblasts following treatment with doxorubicin and tBOOH.
Mareike Döhrmann, Anne Schorr, Johannes Hülsenbeck, Tine L Rasmussen, Olaf-Georg Issinger

Exp Cell Res· April 2012

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Characterization of ATM and DNA-PK wild-type and mutant cell lines upon DSB induction in the presence and absence of CK2 inhibitors.
Birgitte B Olsen, Gerhard Fritz, Olaf-Georg Issinger

Int J Oncol· February 2012

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