Publications by authors named "Virginia Spano"

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Modulators of anion channels and transporters as alternative therapeutic agents to normalize airway surface liquid in cystic fibrosis.
Alessandra Lipani, Fabiana Lo Mascolo, Stefano Giuffrida, Marilia Barreca, Roberta Bivacqua

Eur J Med Chem· January 2026

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In silico-guided exploration of SIRT6 modulation: Discovery of new fragments hits inhibitors.
Ignazio Sardo, Giulia Culletta, Ugo Perricone, Maria De Rosa, Maria Rita Gulotta

J Mol Graph Model· November 2025

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Microwave-Enhanced Synthesis of 2-Styrylquinoline-4-Carboxamides With Promising Anti-Lymphoma Activity.
Ignazio Sardo, Lorenzo Manfreda, Giulia Maria Titone, Marilia Barreca, Roberta Bivacqua

Arch Pharm (Weinheim)· November 2025

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Citrus wastewater as a source of value-added products: Quali-quantitative analysis and in vitro screening on breast cancer cell lines.
Maria Valeria Raimondi, Salvatrice Rigogliuso, Filippo Saiano, Paola Poma, Manuela Labbozzetta

Arch Pharm (Weinheim)· December 2024

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Chaperoning system: Intriguing target to modulate the expression of CFTR in cystic fibrosis.
Federica Scalia, Giulia Culletta, Marilia Barreca, Celeste Caruso Bavisotto, Roberta Bivacqua

Eur J Med Chem· November 2024

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Identification of 6,9-dihydro-5H-pyrrolo[3,2-h]quinazolines as a new class of F508del-CFTR correctors for the treatment of cystic fibrosis.
Marilia Barreca, Mario Renda, Virginia Spanò, Alessandra Montalbano, Maria Valeria Raimondi

Eur J Med Chem· October 2024

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Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.
Marilia Barreca, Virginia Spanò, Roberta Rocca, Roberta Bivacqua, Gianmarco Gualtieri

Eur J Med Chem· June 2023

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Exploring the anticancer activity and the mechanism of action of pyrrolomycins F obtained by microwave-assisted total synthesis.
Marilia Barreca, Miriam Buttacavoli, Gianluca Di Cara, Cesare D'Amico, Emanuela Peri

Eur J Med Chem· May 2023

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Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel.
Mario Renda, Marilia Barreca, Anna Borrelli, Virginia Spanò, Alessandra Montalbano

Sci Rep· May 2023

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Editorial: Emerging heterocycles as bioactive compounds.
Giovanna Li Petri, Ralph Holl, Virginia Spanò, Marilia Barreca, Ignazio Sardo

Front Chem· April 2023

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Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors.
Roberta Bivacqua, Marilia Barreca, Virginia Spanò, Maria Valeria Raimondi, Isabella Romeo

Eur J Med Chem· March 2023

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Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas.
Marilia Barreca, Virginia Spanò, Roberta Rocca, Roberta Bivacqua, Anne-Catherine Abel

Eur J Med Chem· December 2022

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New tricyclic systems as photosensitizers towards triple negative breast cancer cells.
Marilia Barreca, Angela Maria Ingarra, Maria Valeria Raimondi, Virginia Spanò, Antonio Palumbo Piccionello

Arch Pharm Res· November 2022

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Novel insights on [1,2]oxazolo[5,4-e]isoindoles on multidrug resistant acute myeloid leukemia cell line.
Manuela Labbozzetta, Marilia Barreca, Virginia Spanò, Maria Valeria Raimondi, Paola Poma

Drug Dev Res· September 2022

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The New Microtubule-Targeting Agent SIX2G Induces Immunogenic Cell Death in Multiple Myeloma.
Katia Grillone, Caterina Riillo, Roberta Rocca, Serena Ascrizzi, Virginia Spanò

Int J Mol Sci· September 2022

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Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells.
Marilia Barreca, Angela Maria Ingarra, Maria Valeria Raimondi, Virginia Spanò, Michele De Franco

Eur J Med Chem· July 2022

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Synthesis of 2H-Imidazo[2',1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations.
Vincenzo Cilibrasi, Virginia Spanò, Roberta Bortolozzi, Marilia Barreca, Maria Valeria Raimondi

Eur J Med Chem· May 2022

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GPCR Inhibition in Treating Lymphoma.
Marilia Barreca, Virginia Spanò, Maria V Raimondi, Roberta Bivacqua, Stefano Giuffrida

ACS Med Chem Lett· March 2022

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Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds.
Giovanna Li Petri, Maria Valeria Raimondi, Virginia Spanò, Ralph Holl, Paola Barraja

Top Curr Chem (Cham)· August 2021

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Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors.
Virginia Spanò, Marilia Barreca, Roberta Rocca, Roberta Bortolozzi, Ruoli Bai

Eur J Med Chem· February 2021

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Evaluation of Fused Pyrrolothiazole Systems as Correctors of Mutant CFTR Protein.
Virginia Spanò, Marilia Barreca, Vincenzo Cilibrasi, Michele Genovese, Mario Renda

Molecules· February 2021

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Bioactive pyrrole-based compounds with target selectivity.
Giovanna Li Petri, Virginia Spanò, Roberto Spatola, Ralph Holl, Maria Valeria Raimondi

Eur J Med Chem· December 2020

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Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes.
Marilia Barreca, Virginia Spanò, Alessandra Montalbano, Mercedes Cueto, Ana R Díaz Marrero

Mar Drugs· December 2020

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Current development of CFTR potentiators in the last decade.
Virginia Spanò, Arianna Venturini, Michele Genovese, Marilia Barreca, Maria Valeria Raimondi

Eur J Med Chem· October 2020

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Pyrrolo[2',3':3,4]cyclohepta[1,2-][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types.
Virginia Spanò, Roberta Rocca, Marilia Barreca, Daniele Giallombardo, Alessandra Montalbano

J Med Chem· October 2020

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