Publications by authors named "Maria C Manara"

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Genomic profiling of a collection of patient-derived xenografts and cell lines identified ixabepilone as an active drug against chemo-resistant osteosarcoma.
Maria Cristina Manara, Francesca Bruzzese, Laura Formentini, Lorena Landuzzi, Laura Pazzaglia

J Exp Clin Cancer Res· July 2025

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CD99: A Key Regulator in Immune Response and Tumor Microenvironment.
Maria Cristina Manara, Valentina Fiori, Angelo Sparti, Katia Scotlandi

Biomolecules· April 2025

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CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1-targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape.
Michela Pasello, Maria Antonella Laginestra, Maria Cristina Manara, Lorena Landuzzi, Francesca Ruzzi

J Cell Commun Signal· September 2024

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Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma.
Daniel Fowler, Marta Barisa, Alba Southern, Callum Nattress, Elizabeth Hawkins, Maria C Manara

Sci Transl Med· May 2024

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Engagement of CD99 Activates Distinct Programs in Ewing Sarcoma and Macrophages.
Maria Cristina Manara, Cristina Manferdini, Camilla Cristalli, Marianna Carrabotta, Spartaco Santi

Cancer Immunol Res· February 2024

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IL-1 Family Members in Bone Sarcomas.
Lorena Landuzzi, Francesca Ruzzi, Evelin Pellegrini, Pier-Luigi Lollini, Katia Scotlandi, Maria Cristina Manara

Cells· January 2024

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Innovative Breakthroughs for the Treatment of Advanced and Metastatic Synovial Sarcoma.
Lorena Landuzzi, Maria Cristina Manara, Laura Pazzaglia, Pier-Luigi Lollini, Katia Scotlandi

Cancers (Basel)· July 2023

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ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis.
Michela Pasello, Anna Maria Giudice, Camilla Cristalli, Maria Cristina Manara, Caterina Mancarella

Cell Oncol (Dordr)· December 2022

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Correction to: ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis.
Michela Pasello, Anna Maria Giudice, Camilla Cristalli, Maria Cristina Manara, Caterina Mancarella

Cell Oncol (Dordr)· December 2022

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Correction: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Clemens Zwergel, Michael Schnekenburger, Federica Sarno, Cecilia Battistelli, Maria Cristina Manara

Clin Epigenetics· September 2022

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A 3D Collagen-Based Bioprinted Model to Study Osteosarcoma Invasiveness and Drug Response.
Evelin Pellegrini, Giovanna Desando, Mauro Petretta, Antonella Cellamare, Camilla Cristalli, Maria Cristina Manara

Polymers (Basel)· September 2022

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Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response.
Camilla Cristalli, Maria Cristina Manara, Sergio Valente, Evelin Pellegrini, Alberto Bavelloni

Front Endocrinol (Lausanne)· June 2022

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Bone Turnover Marker (BTM) Changes after Denosumab in Giant Cell Tumors of Bone (GCTB): A Phase II Trial Correlative Study.
Emanuela Palmerini, Laura Pazzaglia, Luca Cevolani, Loredana Pratelli, Michela Pierini, Maria Cristina Manara

Cancers (Basel)· June 2022

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Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma.
Francesca Chiarini, Francesca Paganelli, Tommaso Balestra, Cristina Capanni, Antonietta Fazio, Maria Cristina Manara

Cell Death Dis· April 2022

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Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma.
Marianna Carrabotta, Maria Antonella Laginestra, Giorgio Durante, Caterina Mancarella, Lorena Landuzzi, Maria Cristina Manara

Cancer Res· February 2022

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Targeting CD99 Compromises the Oncogenic Effects of the Chimera EWS-FLI1 by Inducing Reexpression of Zyxin and Inhibition of GLI1 Activity.
Tommaso Balestra, Maria Cristina Manara, Maria Antonella Laginestra, Michela Pasello, Alessandra De Feo

Mol Cancer Ther· January 2022

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Impact of ABC Transporters in Osteosarcoma and Ewing's Sarcoma: Which Are Involved in Chemoresistance and Which Are Not?
Massimo Serra, Claudia Maria Hattinger, Michela Pasello, Chiara Casotti, Leonardo Fantoni, Maria Cristina Manara

Cells· September 2021

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Ewing Sarcoma PDX Models.
Didier Surdez, Lorena Landuzzi, Katia Scotlandi, Maria Cristina Manara

Methods Mol Biol· April 2021

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Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma.
Lorena Landuzzi, Maria Cristina Manara, Pier-Luigi Lollini, Katia Scotlandi

Cells· February 2021

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Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma.
Marika Sciandra, Alessandra De Feo, Alessandro Parra, Lorena Landuzzi, Pier-Luigi Lollini, Maria Cristina Manara

J Cell Commun Signal· September 2020

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Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis.
Caterina Mancarella, Giulia Caldoni, Irene Ribolsi, Alessandro Parra, Maria Cristina Manara

Front Oncol· July 2020

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ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity.
Cinzia Zucchini, Maria Cristina Manara, Camilla Cristalli, Marianna Carrabotta, Sara Greco

J Exp Clin Cancer Res· December 2019

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Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations.
Patrizia Nanni, Lorena Landuzzi, Maria Cristina Manara, Alberto Righi, Giordano Nicoletti

Sci Rep· August 2019

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Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Clemens Zwergel, Michael Schnekenburger, Federica Sarno, Cecilia Battistelli, Maria Cristina Manara

Clin Epigenetics· May 2019

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Oxidative Stress in Autistic Children Alters Erythrocyte Shape in the Absence of Quantitative Protein Alterations and of Loss of Membrane Phospholipid Asymmetry.
Alessandra Bolotta, Michela Battistelli, Elisabetta Falcieri, Alessandro Ghezzo, Maria Cristina Manara

Oxid Med Cell Longev· February 2019

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