Publications by authors named "Maria G Rotordam"

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Piezo1 Channel Activators Yoda1 and Yoda2 in the Context of Red Blood Cells.
Min Qiao, Reetta Penttinen, Ariel Coli, Nicoletta Murciano, Felix M Maurer, Maria Giustina Rotordam

Biomolecules· August 2025

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The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells.
Polina Petkova-Kirova, Nicoletta Murciano, Giulia Iacono, Julia Jansen, Greta Simionato, Maria Giustina Rotordam

Int J Mol Sci· January 2024

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A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation.
Nicoletta Murciano, Maria Giustina Rotordam, Nadine Becker, Melanie J Ludlow, Gregory Parsonage

J Gen Physiol· December 2023

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Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1.
Gregory Parsonage, Kevin Cuthbertson, Naima Endesh, Nicoletta Murciano, Adam J Hyman, Maria Giustina Rotordam

Br J Pharmacol· August 2023

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There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments.
Markus Rapedius, Alison Obergrussberger, Edward S A Humphries, Stephanie Scholz, Ilka Rinke-Weiss, Maria Giustina Rotordam

Front Mol Neurosci· August 2022

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Transient receptor potential channel vanilloid type 2 in red cells of cannabis consumer.
Daniel Flormann, Min Qiao, Nicoletta Murciano, Giulia Iacono, Alexis Darras, Maria Giustina Rotordam

Am J Hematol· May 2022

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The suitability of high throughput automated patch clamp for physiological applications.
Alison Obergrussberger, Ilka Rinke-Weiß, Tom A Goetze, Markus Rapedius, Nina Brinkwirth, Maria Giustina Rotordam

J Physiol· January 2022

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Altered Ca Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis.
Ralfs Buks, Tracy Dagher, Maria Giustina Rotordam, David Monedero Alonso, Sylvie Cochet

Cells· December 2021

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Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment.
Maria Giustina Rotordam, Alison Obergrussberger, Nina Brinkwirth, Kiyoshi Takasuna, Nadine Becker

J Pharmacol Toxicol Methods· November 2021

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A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.
Xiaomei Han, Mohammadreza Samieegohar, Bradley J Ridder, Wendy W Wu, Aaron Randolph, Maria Giustina Rotordam

J Pharmacol Toxicol Methods· September 2020

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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Maria Giustina Rotordam

Toxicol Appl Pharmacol· May 2020

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Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Maria Giustina Rotordam

Toxicol Appl Pharmacol· May 2020

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A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp.
Maria G Rotordam, Elisa Fermo, Nadine Becker, Wilma Barcellini, Andrea Brüggemann

Haematologica· May 2019

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