Publications by authors named "Maria P Limberis"

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SP-101, A Novel Adeno-Associated Virus Gene Therapy for the Treatment of Cystic Fibrosis, Mediates Functional Correction of Primary Human Airway Epithelia From Donors with Cystic Fibrosis.
Katherine J D A Excoffon, Shen Lin, Poornima Kotha Lakshmi Narayan, Sneha Sitaraman, Awal M Jimah, Maria P Limberis

Hum Gene Ther· September 2024

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Inhalation of SP-101 Followed by Inhaled Doxorubicin Results in Robust and Durable Transgene Expression in the Airways of Wild-Type and Cystic Fibrosis Ferrets.
Katherine J D A Excoffon, Mark D Smith, Lillian Falese, Robert Schulingkamp, Shen Lin, Maria P Limberis

Hum Gene Ther· September 2024

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Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRΔR gene delivery to adult ferret lungs.
Yinghua Tang, Mehrnoosh Ebadi, Junying Lei, Zehua Feng, Shahab Fakhari, Maria P Limberis

Mol Ther Methods Clin Dev· June 2024

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Restoring Ciliary Function: Gene Therapeutics for Primary Ciliary Dyskinesia.
Nicholas W Keiser, Erin Cant, Sneha Sitaraman, Amelia Shoemark, Maria P Limberis

Hum Gene Ther· September 2023

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Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs.
Yinghua Tang, Shahab Fakhari, Eric D Huntemann, Zehua Feng, Peipei Wu, Maria P Limberis

Mol Ther Methods Clin Dev· June 2023

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Gene Therapeutics for Surfactant Dysfunction Disorders: Targeting the Alveolar Type 2 Epithelial Cell.
Sneha Sitaraman, Konstantinos-Dionysios Alysandratos, Jennifer A Wambach, Maria P Limberis

Hum Gene Ther· October 2022

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Heart of the Matter: AAV8 Improves Cardiac Function.
Maria P Limberis

Hum Gene Ther· October 2022

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Adeno-Associated Virus Vector-Mediated Expression of Antirespiratory Syncytial Virus Antibody Prevents Infection in Mouse Airways.
Josh Tycko, Virginie S Adam, Marco Crosariol, Jason Ohlstein, Julio Sanmiguel, Maria P Limberis

Hum Gene Ther· December 2021

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Preclinical Development of a HIV-Based Gene Therapeutic for Cystic Fibrosis Pulmonary Disease.
Maria P Limberis

Hum Gene Ther· August 2021

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Breathing Easier: Molecular Therapeutics for Cystic Fibrosis.
Maria P Limberis

Hum Gene Ther· September 2020

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Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning.
Vibhor Gupta, C Linn Cadieux, Deirdre McMenamin, C Angelica Medina-Jaszek, Muhammad Arif, Maria P Limberis

PLoS One· March 2020

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Intrathecal Viral Vector Delivery of Trastuzumab Prevents or Inhibits Tumor Growth of Human HER2-Positive Xenografts in Mice.
William T Rothwell, Peter Bell, Laura K Richman, Maria P Limberis, Anna P Tretiakova

Cancer Res· November 2018

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Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Nick S Laursen, Robert H E Friesen, Xueyong Zhu, Mandy Jongeneelen, Sven Blokland, Maria P Limberis

Science· November 2018

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Preparation of Nonhuman Primate Eyes for Histological Evaluation After Retinal Gene Transfer.
Peter Bell, Hongwei Yu, Leah Kuntz, Omua Ahonkhai, Anna Tretiakova, Maria P Limberis

Hum Gene Ther Methods· June 2018

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Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia.
Jenny A Greig, Maria P Limberis, Peter Bell, Shu-Jen Chen, Roberto Calcedo

Hum Gene Ther Clin Dev· March 2017

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Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR Rhesus Macaques.
Jenny A Greig, Maria P Limberis, Peter Bell, Shu-Jen Chen, Roberto Calcedo

Hum Gene Ther Clin Dev· March 2017

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Adeno-Associated Virus Serotype 9-Expressed ZMapp in Mice Confers Protection Against Systemic and Airway-Acquired Ebola Virus Infection.
Maria P Limberis, Anna Tretiakova, Kalyani Nambiar, Gary Wong, Trina Racine

J Infect Dis· December 2016

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Vector serotype screening for use in ovine perinatal lung gene therapy.
Lauren E McClain, Marcus G Davey, Phillip W Zoltick, Maria P Limberis, Alan W Flake

J Pediatr Surg· June 2016

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Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.
Eric W F W Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Maria P Limberis

Lancet Respir Med· September 2015

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In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection.
Melissa Myint, Maria P Limberis, Peter Bell, Suryanarayan Somanathan, Angela Haczku

Hum Gene Ther· November 2014

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Adeno-associated virus 9-mediated airway expression of antibody protects old and immunodeficient mice against influenza virus.
Virginie S Adam, Marco Crosariol, Sachin Kumar, Moyar Q Ge, Sarah E Czack, Maria P Limberis

Clin Vaccine Immunol· November 2014

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In utero lung gene transfer using adeno-associated viral and lentiviral vectors in mice.
Luc Joyeux, Enrico Danzer, Maria P Limberis, Philip W Zoltick, Antoneta Radu

Hum Gene Ther Methods· June 2014

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Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.
Shu-Jen Chen, Julio Sanmiguel, Martin Lock, Deirdre McMenamin, Christine Draper, Maria P Limberis

Hum Gene Ther Clin Dev· December 2013

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Vectored expression of the broadly neutralizing antibody FI6 in mouse airway provides partial protection against a new avian influenza A virus, H7N9.
Maria P Limberis, Trina Racine, Darwyn Kobasa, Yan Li, George F Gao

Clin Vaccine Immunol· December 2013

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