Publications by authors named "Maria Papathanasopoulos"

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Causes of death in adults living with HIV in South Africa: A single-centre postmortem study.
Tanvier Omar, Nadia Sabet, Alistair Calver, Gajendra Chita, Lucas E Hermans, Maria Papathanasopoulos

South Afr J HIV Med· May 2025

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Thymidine Analogue Mutations with M184V Significantly Decrease Phenotypic Susceptibility of HIV-1 Subtype C Reverse Transcriptase to Islatravir.
Hyeonah Byun, Maria Antonia Papathanasopoulos, Kim Steegen, Adriaan Erasmus Basson

Viruses· December 2024

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Steatotic liver disease in people with HIV at Tshepong Hospital: A post-mortem analysis.
Aqeela Moosa, Ebrahim Variava, Alistair D Calver, Gajendra Chita, Nadia Sabet, Maria Papathanasopoulos

South Afr J HIV Med· December 2024

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K103N, V106M and Y188L Significantly Reduce HIV-1 Subtype C Phenotypic Susceptibility to Doravirine.
Nikita Reddy, Maria Papathanasopoulos, Kim Steegen, Adriaan Erasmus Basson

Viruses· September 2024

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Ibogaine administration following repeated morphine administration upregulates myelination markers 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and myelin basic protein (MBP) mRNA and protein expression in the internal capsule of Sprague Dawley rats.
Demi Govender, Leila Moloko, Maria Papathanasopoulos, Nancy Tumba, Gavin Owen

Front Neurosci· July 2024

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Shifting the center of gravity for addressing the rising cancer disease burden in Africa: A rationale for African-based integrative infectious diseases and oncology research.
Robert F Breiman, Georgia Demetriou, Gita Naidu, Maria A Papathanasopoulos, Paul Ruff

PLOS Glob Public Health· May 2023

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Immunization with HIV-1 trimeric SOSIP.664 BG505 or founder virus C (FVC) covalently complexed to two-domain CD4 elicits cross-clade neutralizing antibodies in New Zealand white rabbits.
Nancy L Tumba, Gavin R Owen, Mark A Killick, Maria A Papathanasopoulos

Vaccine X· December 2022

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HIV-1 bispecific antibody iMab-N6 exhibits enhanced breadth but not potency over its parental antibodies iMab and N6.
Tumelo Moshoette, Maria Antonia Papathanasopoulos, Mark Andrew Killick

Virol J· September 2022

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Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics.
Nancy L Tumba, Previn Naicker, Stoyan Stoychev, Mark A Killick, Gavin R Owen, Maria A Papathanasopoulos

Biochem Biophys Res Commun· July 2022

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Immune activation correlates with and predicts CXCR4 co-receptor tropism switch in HIV-1 infection.
Bridgette J Connell, Lucas E Hermans, Annemarie M J Wensing, Ingrid Schellens, Pauline J Schipper, Maria A Papathanasopoulos

Sci Rep· September 2020

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Engineering and characterising a novel, highly potent bispecific antibody iMab-CAP256 that targets HIV-1.
Tumelo Moshoette, Stuart Alvaro Ali, Maria Antonia Papathanasopoulos, Mark Andrew Killick

Retrovirology· November 2019

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An update on the biophysical character of the human eukaryotic elongation factor 1 beta: Perspectives from interaction with elongation factor 1 gamma.
Ikechukwu Achilonu, Nnenna Elebo, Babongiwe Hlabano, Gavin R Owen, Maria Papathanasopoulos

J Mol Recognit· July 2018

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HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052.
Philip J Palumbo, Jessica M Fogel, Sarah E Hudelson, Ethan A Wilson, Stephen Hart, Maria A Papathanasopoulos

J Acquir Immune Defic Syndr· April 2018

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Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control.
Gavin R Owen, Doris Le, Stoyan Stoychev, Nichole M Cerutti, Maria Papathanasopoulos

Biochem Biophys Res Commun· March 2018

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Moderate Levels of Pre-Treatment HIV-1 Antiretroviral Drug Resistance Detected in the First South African National Survey.
Kim Steegen, Sergio Carmona, Michelle Bronze, Maria A Papathanasopoulos, Gert van Zyl

PLoS One· June 2017

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Molecular characterisation of rifampicin-resistant strains from Malawi.
Tarsizio Chikaonda, Irene Ketseoglou, Nelson Nguluwe, Robert Krysiak, Isaac Thengolose, Maria A Papathanasopoulos

Afr J Lab Med· March 2017

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Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry.
Naazneen Moolla, Mark Killick, Maria Papathanasopoulos, Alexio Capovilla

Biochim Biophys Acta· September 2016

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Functional roles of HIV-1 Vpu and CD74: Details and implications of the Vpu-CD74 interaction.
Denise A Le Noury, Salerwe Mosebi, Maria A Papathanasopoulos, Raymond Hewer

Cell Immunol· April 2016

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Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2.
Gavin R Owen, Jennifer A Channell, V Trevor Forsyth, Michael Haertlein, Edward P Mitchell, Maria Papathanasopoulos

Biochemistry· April 2016

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Env-2dCD4 S60C complexes act as super immunogens and elicit potent, broadly neutralizing antibodies against clinically relevant human immunodeficiency virus type 1 (HIV-1).
Mark A Killick, Michelle L Grant, Nichole M Cerutti, Alexio Capovilla, Maria A Papathanasopoulos

Vaccine· November 2015

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High prevalence of the K65R mutation in HIV-1 subtype C infected patients failing tenofovir-based first-line regimens in South Africa.
Lindiwe Skhosana, Kim Steegen, Michelle Bronze, Azwidowi Lukhwareni, Esrom Letsoalo, Maria A Papathanasopoulos

PLoS One· October 2015

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Design, Synthesis, and Biological Evaluation of 1,2-Dihydroisoquinolines as HIV-1 Integrase Inhibitors.
Vibha Tandon, Urvashi, Pooja Yadav, Souvik Sur, Sheenu Abbat, Maria A Papathanasopoulos

ACS Med Chem Lett· October 2015

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High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen.
Kim Steegen, Leon Levin, Irene Ketseoglou, Michelle Bronze, Maria A Papathanasopoulos

PLoS One· June 2015

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The evaluation of statins as potential inhibitors of the LEDGF/p75-HIV-1 integrase interaction.
Angela T Harrison, Frederik H Kriel, Maria A Papathanasopoulos, Salerwe Mosebi, Shaakira Abrahams

Chem Biol Drug Des· March 2015

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Generation and characterization of an HIV-1 subtype C transmitted and early founder virus consensus sequence.
Mark Killick, Alexio Capovilla, Maria A Papathanasopoulos

AIDS Res Hum Retroviruses· October 2014

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