Publications by authors named "Mark Killick"

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Immunization with HIV-1 trimeric SOSIP.664 BG505 or founder virus C (FVC) covalently complexed to two-domain CD4 elicits cross-clade neutralizing antibodies in New Zealand white rabbits.
Nancy L Tumba, Gavin R Owen, Mark A Killick, Maria A Papathanasopoulos

Vaccine X· December 2022

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HIV-1 bispecific antibody iMab-N6 exhibits enhanced breadth but not potency over its parental antibodies iMab and N6.
Tumelo Moshoette, Maria Antonia Papathanasopoulos, Mark Andrew Killick

Virol J· September 2022

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Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics.
Nancy L Tumba, Previn Naicker, Stoyan Stoychev, Mark A Killick, Gavin R Owen

Biochem Biophys Res Commun· July 2022

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Engineering and characterising a novel, highly potent bispecific antibody iMab-CAP256 that targets HIV-1.
Tumelo Moshoette, Stuart Alvaro Ali, Maria Antonia Papathanasopoulos, Mark Andrew Killick

Retrovirology· November 2019

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Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry.
Naazneen Moolla, Mark Killick, Maria Papathanasopoulos, Alexio Capovilla

Biochim Biophys Acta· September 2016

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Env-2dCD4 S60C complexes act as super immunogens and elicit potent, broadly neutralizing antibodies against clinically relevant human immunodeficiency virus type 1 (HIV-1).
Mark A Killick, Michelle L Grant, Nichole M Cerutti, Alexio Capovilla, Maria A Papathanasopoulos

Vaccine· November 2015

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Generation and characterization of an HIV-1 subtype C transmitted and early founder virus consensus sequence.
Mark Killick, Alexio Capovilla, Maria A Papathanasopoulos

AIDS Res Hum Retroviruses· October 2014

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Disulfide reduction in CD4 domain 1 or 2 is essential for interaction with HIV glycoprotein 120 (gp120), which impairs thioredoxin-driven CD4 dimerization.
Nichole Cerutti, Mark Killick, Vinesh Jugnarain, Maria Papathanasopoulos, Alexio Capovilla

J Biol Chem· April 2014

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Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange.
Nichole Cerutti, Barry V Mendelow, Grant B Napier, Maria A Papathanasopoulos, Mark Killick

J Biol Chem· August 2010

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