Publications by authors named "Maria R Pasca"

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Advancing the antituberculosis activity of nitropicolinic acids and amides.
Andrew M Thompson, Chen-Yi Cheung, Matthew B McNeil, Ashley C Campbell, Monika Záhorszká, Maria Rosalia Pasca

Eur J Med Chem· January 2026

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Uncovering Insights Into the Biology of Mycobacterium tuberculosis Using Genetic Tools.
Alessandro Stamilla, Deborah Recchia, Giovanni Stelitano, Ludovica Maci, Maria Concetta Marturano, Maria Rosalia Pasca

Microbiologyopen· December 2025

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Targeting virulence in Mycobacterium tuberculosis and nontuberculous mycobacteria: Focus on anti-infective drug design.
Laurent Robert Chiarelli, Alexander Lepioshkin, Maria Rosalia Pasca, Vadim Makarov

Drug Discov Today· November 2025

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Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound.
Deborah Recchia, Giovanni Stelitano, Anna Egorova, Gherard Batisti Biffignandi, Karin Savková, Maria Rosalia Pasca

ACS Infect Dis· April 2025

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Protocol to quantify bacterial burden in time-kill assays using colony-forming units and most probable number readouts for Mycobacterium tuberculosis.
Marie Sylvianne Rabodoarivelo, Eik Hoffmann, Cyril Gaudin, Diana Angélica Aguilar-Ayala, Jordana Galizia, Maria Rosalia Pasca

STAR Protoc· March 2025

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The novel drug candidate VOMG kills Mycobacterium abscessus and other pathogens by inhibiting cell division.
Giulia Degiacomi, Laurent R Chiarelli, Olga Riabova, Nicola Ivan Loré, Lara Muñoz-Muñoz, Maria Rosalia Pasca

Int J Antimicrob Agents· October 2024

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Imidazoquinoline Derivatives as Potential Inhibitors of InhA Enzyme and .
Pascal Hoffmann, Joëlle Azéma-Despeyroux, Fernanda Goncalves, Alessandro Stamilla, Nathalie Saffon-Merceron, Maria Rosalia Pasca

Molecules· June 2024

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Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors.
Rasoul Tamhaev, Emeline Grosjean, Hikmat Ahamed, Mélina Chebaiki, Frédéric Rodriguez, Maria Rosalia Pasca

Bioorg Chem· February 2024

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CanB, a Druggable Cellular Target in .
Giulia Degiacomi, Beatrice Gianibbi, Deborah Recchia, Giovanni Stelitano, Giuseppina Ivana Truglio, Maria Rosalia Pasca

ACS Omega· July 2023

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Implementing best practices on data generation and reporting of assays within the ERA4TB consortium.
Rob C van Wijk, Ainhoa Lucía, Pavan Kumar Sudhakar, Lindsay Sonnenkalb, Cyril Gaudin, Maria Rosalia Pasca

iScience· April 2023

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Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options.
Deborah Recchia, Giovanni Stelitano, Alessandro Stamilla, Damaris L Gutierrez, Giulia Degiacomi, Maria Rosalia Pasca

Int J Mol Sci· February 2023

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Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization.
Miriam Girardini, Francesca Ferlenghi, Giannamaria Annunziato, Giulia Degiacomi, Bianca Papotti, Maria Rosalia Pasca

Eur J Med Chem· January 2023

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A New Benzothiazolthiazolidine Derivative, 11726172, Is Active , , and against Nonreplicating Cells of Mycobacterium tuberculosis.
Elena G Salina, Umberto Postiglione, Laurent R Chiarelli, Deborah Recchia, Monika Záhorszká, Maria Rosalia Pasca

mSphere· December 2022

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New Drugs and Novel Cellular Targets against Tuberculosis.
Giulia Degiacomi, Vadim Makarov, Maria Rosalia Pasca, Laurent Roberto Chiarelli

Int J Mol Sci· November 2022

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The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the DprE1 Enzyme.
José Manuel Ezquerra-Aznárez, Giulia Degiacomi, Henrich Gašparovič, Giovanni Stelitano, Josè Camilla Sammartino, Maria Rosalia Pasca

Int J Mol Sci· January 2022

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The Antimalarial Mefloquine Shows Activity against , Inhibiting Mycolic Acid Metabolism.
Giulia Degiacomi, Laurent Roberto Chiarelli, Deborah Recchia, Elena Petricci, Beatrice Gianibbi, Maria Rosalia Pasca

Int J Mol Sci· August 2021

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Editorial: New Approaches Against Drug-Resistant .
Yossef Av-Gay, Giorgia Mori, Maria Rosalia Pasca

Front Microbiol· April 2021

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A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in .
Asma Farjallah, Laurent R Chiarelli, Martin Forbak, Giulia Degiacomi, Mathieu Danel, Maria Rosalia Pasca

ACS Infect Dis· March 2021

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Nitric oxide-releasing compounds for the treatment of lung infections.
Laurent R Chiarelli, Giulia Degiacomi, Anna Egorova, Vadim Makarov, Maria Rosalia Pasca

Drug Discov Today· February 2021

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Design and Synthesis of Pyrano[3,2-]indolones Showing Antimycobacterial Activity.
Natalia Monakhova, Jana Korduláková, Anthony Vocat, Anna Egorova, Alexander Lepioshkin, Maria Rosalia Pasca

ACS Infect Dis· January 2021

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Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer.
Giorgia Mori, Maria Rosalia Pasca

Int J Mol Sci· January 2021

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Study of Bedaquiline Resistance in Multi-Drug Resistant Clinical Isolates.
Giulia Degiacomi, José Camilla Sammartino, Virginia Sinigiani, Paola Marra, Alice Urbani, Maria Rosalia Pasca

Front Microbiol· September 2020

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2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry.
Elisa Azzali, Miriam Girardini, Giannamaria Annunziato, Marialaura Pavone, Federica Vacondio, Maria Rosalia Pasca

ACS Med Chem Lett· July 2020

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Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug.
Giorgia Mori, Beatrice Silvia Orena, Laurent R Chiarelli, Giulia Degiacomi, Olga Riabova, Maria Rosalia Pasca

Front Microbiol· February 2020

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First triclosan-based macrocyclic inhibitors of InhA enzyme.
Frédéric Rodriguez, Nathalie Saffon, José Camilla Sammartino, Giulia Degiacomi, Maria Rosalia Pasca

Bioorg Chem· January 2020

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