Publications by authors named "Mariappan Chelliah"

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Modeling Approaches to Reimagine Stability (MARS) for Enabling Earlier Access to Critical Drugs for Patients with Unmet Medical Needs.
M Scott Furness, Hong Cai, Sithamalli Chandramouli, Mariappan Chelliah, Xiao Hong Chen

AAPS PharmSciTech· January 2023

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Discovery of hydroxy pyrimidine Factor IXa inhibitors.
Charles L Jayne, Teresa Andreani, Tin-Yau Chan, Mariappan V Chelliah, Martin C Clasby

Bioorg Med Chem Lett· August 2020

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Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists.
Jason M Cox, Hong D Chu, Mariappan V Chelliah, John S Debenham, Keith Eagen

ACS Med Chem Lett· January 2017

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Design and Synthesis of P2-P4 Macrocycles Containing a Unique Spirocyclic Proline: A New Class of HCV NS3/4A Inhibitors.
Francisco Velázquez, Mariappan Chelliah, Martin Clasby, Zhuyan Guo, John Howe

ACS Med Chem Lett· December 2016

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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.
Santhosh F Neelamkavil, Sony Agrawal, Thomas Bara, Chad Bennett, Sathesh Bhat, Mariappan Chelliah

ACS Med Chem Lett· January 2016

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Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.
Mariappan V Chelliah, Keith Eagen, Zhuyan Guo, Samuel Chackalamannil, Yan Xia

ACS Med Chem Lett· May 2014

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Himbacine-derived thrombin receptor antagonists: c7-aminomethyl and c9a-hydroxy analogues of vorapaxar.
Mariappan V Chelliah, Samuel Chackalamannil, Yan Xia, William J Greenlee, Ho-Sam Ahn

ACS Med Chem Lett· February 2014

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Discovery of nor-seco himbacine analogs as thrombin receptor antagonists.
Mariappan V Chelliah, Samuel Chackalamannil, Yan Xia, Keith Eagen, William J Greenlee

Bioorg Med Chem Lett· April 2012

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Heterotricyclic himbacine analogs as potent, orally active thrombin receptor (protease activated receptor-1) antagonists.
Mariappan V Chelliah, Samuel Chackalamannil, Yan Xia, Keith Eagen, Martin C Clasby

J Med Chem· October 2007

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Total synthesis of (-)-himgaline.
Unmesh Shah, Samuel Chackalamannil, Ashit K Ganguly, Mariappan Chelliah, Sergei Kolotuchin

J Am Chem Soc· October 2006

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