Publications by authors named "Unmesh Shah"

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Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists.
Jason M Cox, Hong D Chu, Mariappan V Chelliah, John S Debenham, Keith Eagen, Unmesh Shah

ACS Med Chem Lett· January 2017

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Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with Activity in Rodents.
Gregory L Adams, Francisco Velazquez, Charles Jayne, Unmesh Shah, Shouwu Miao

ACS Med Chem Lett· January 2017

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Design and Synthesis of P2-P4 Macrocycles Containing a Unique Spirocyclic Proline: A New Class of HCV NS3/4A Inhibitors.
Francisco Velázquez, Mariappan Chelliah, Martin Clasby, Zhuyan Guo, John Howe, Unmesh Shah

ACS Med Chem Lett· December 2016

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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.
Santhosh F Neelamkavil, Sony Agrawal, Thomas Bara, Chad Bennett, Sathesh Bhat, Unmesh Shah

ACS Med Chem Lett· January 2016

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Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors.
Unmesh Shah, Charles Jayne, Samuel Chackalamannil, Francisco Velázquez, Zhuyan Guo

ACS Med Chem Lett· March 2014

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GPR119 agonists for the potential treatment of type 2 diabetes and related metabolic disorders.
Unmesh Shah, Timothy J Kowalski

Vitam Horm· April 2011

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Recent progress in the discovery of adenosine A(2A) receptor antagonists for the treatment of Parkinson's disease.
Unmesh Shah, Robert Hodgson

Curr Opin Drug Discov Devel· July 2010

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Azabicyclic sulfonamides as potent 11beta-HSD1 inhibitors.
Unmesh Shah, Craig D Boyle, Samuel Chackalamannil, Hana Baker, Timothy Kowalski

Bioorg Med Chem Lett· March 2010

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GPR119 agonists: a promising new approach for the treatment of type 2 diabetes and related metabolic disorders.
Unmesh Shah

Curr Opin Drug Discov Devel· July 2009

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Design, synthesis, and evaluation of fused heterocyclic analogs of SCH 58261 as adenosine A2A receptor antagonists.
Unmesh Shah, Claire M Lankin, Craig D Boyle, Samuel Chackalamannil, William J Greenlee

Bioorg Med Chem Lett· July 2008

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Biaryl and heteroaryl derivatives of SCH 58261 as potent and selective adenosine A2A receptor antagonists.
Unmesh Shah, Craig D Boyle, Samuel Chackalamannil, Bernard R Neustadt, Neil Lindo

Bioorg Med Chem Lett· July 2008

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Total synthesis of (-)-himgaline.
Unmesh Shah, Samuel Chackalamannil, Ashit K Ganguly, Mariappan Chelliah, Sergei Kolotuchin

J Am Chem Soc· October 2006

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