Publications by authors named "Marijane Russell"

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Predicting the Conformational Variability of Abl Tyrosine Kinase using Molecular Dynamics Simulations and Markov State Models.
Yilin Meng, Cen Gao, David K Clawson, Shane Atwell, Marijane Russell

J Chem Theory Comput· May 2018

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Synthesis and Pharmacological Characterization of C4-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu Receptor Agonist.
James A Monn, Steven S Henry, Steven M Massey, David K Clawson, Qi Chen, Marijane Russell

J Med Chem· March 2018

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Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery.
Joey P Ting, Frances Tung, Stephen Antonysamy, Stephen Wasserman, Spencer B Jones, Marijane Russell

PLoS One· February 2018

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Correction to The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD(+)) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition.
Xun Zhao, Dagart Allison, Bradley Condon, Feiyu Zhang, Tarun Gheyi, Marijane Russell

J Med Chem· March 2016

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Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist.
James A Monn, Lourdes Prieto, Lorena Taboada, Junliang Hao, Matthew R Reinhard, Marijane Russell

J Med Chem· September 2015

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Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics.
John Gately Luz, Stephen Antonysamy, Steven L Kuklish, Bradley Condon, Matthew R Lee, Marijane Russell

J Med Chem· June 2015

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Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.
James A Monn, Lourdes Prieto, Lorena Taboada, Concepcion Pedregal, Junliang Hao, Marijane Russell

J Med Chem· February 2015

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Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain.
Stephen Antonysamy, Bradley Condon, Zhanna Druzina, Jeffrey B Bonanno, Tarun Gheyi, Marijane Russell

PLoS One· October 2014

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The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition.
Xun Zhao, Dagart Allison, Bradley Condon, Feiyu Zhang, Tarun Gheyi, Marijane Russell

J Med Chem· February 2013

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Crystal structure of the human PRMT5:MEP50 complex.
Stephen Antonysamy, Zahid Bonday, Robert M Campbell, Brandon Doyle, Zhanna Druzina, Marijane Russell

Proc Natl Acad Sci U S A· October 2012

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Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.
Chintan K Kikani, Stephen A Antonysamy, Jeffrey B Bonanno, Rich Romero, Feiyu Fred Zhang, Marijane Russell

J Biol Chem· December 2010

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Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.
John Jeff Alvarado, Anjana Nemkal, J Michael Sauder, Marijane Russell, Donna E Akiyoshi

Mol Biochem Parasitol· December 2009

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SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Sean G Buchanan, Jorg Hendle, Patrick S Lee, Christopher R Smith, Pierre-Yves Bounaud, Marijane Russell

Mol Cancer Ther· December 2009

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A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.
Shane Atwell, Jason M Adams, John Badger, Michelle D Buchanan, Ingeborg K Feil, Marijane Russell

J Biol Chem· December 2004

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