Publications by authors named "Mario Sechi"

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Design, anticancer activity, and mechanistic evaluation of a novel class of selective human carbonic anhydrase IX inhibitors featuring a trifluorodihydroxypropanone pharmacophore.
Nicolino Pala, Federico Ladu, Wojciech Szlasa, Roberta Cadoni, Carrie Lomelino, Mario Sechi

Eur J Med Chem· November 2025

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RNA Nanoparticles Harboring Radioisotopes or Other Imaging Molecules for Spontaneous Tumor Targeting for Early Cancer Diagnosis.
Daniel W Binzel, Congcong Xu, Katherine Binzel, Arijit Ghosh, Adam Pippin, Mario Sechi

RNA Nanomed· August 2025

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EGCG Disrupts the LIN28B/Let-7 Interaction and Reduces Neuroblastoma Aggressiveness.
Simona Cocchi, Valentina Greco, Viktoryia Sidarovich, Jacopo Vigna, Francesca Broso, Mario Sechi

Int J Mol Sci· April 2024

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Synthesis, modelling, and biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents.
Samuel T Boateng, Tithi Roy, Kara Torrey, Uchechi Owunna, Sergette Banang-Mbeumi, Mario Sechi

J Enzyme Inhib Med Chem· December 2023

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α-Glucosidase inhibition by green, white and oolong teas: activity and computational studies.
Fabio Esposito, Nicolino Pala, Mauro Carcelli, Samuel T Boateng, Paolo S D'Aquila, Mario Sechi

J Enzyme Inhib Med Chem· December 2023

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Development of targeted nanoparticles loaded with antiviral drugs for SARS-CoV-2 inhibition.
Vanna Sanna, Sandro Satta, Tzung Hsiai, Mario Sechi

Eur J Med Chem· March 2022

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Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation.
Tithi Roy, Samuel T Boateng, Sergette Banang-Mbeumi, Pankaj K Singh, Pratik Basnet, Mario Sechi

Data Brief· April 2021

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Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers.
Tithi Roy, Samuel T Boateng, Sergette Banang-Mbeumi, Pankaj K Singh, Pratik Basnet, Mario Sechi

Bioorg Chem· February 2021

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Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales.
Yaiza Fernández-García, Sebastiaan Ter Horst, Marcella Bassetto, Andrea Brancale, Johan Neyts, Mario Sechi

Antiviral Res· November 2020

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Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture.
Nicolino Pala, Francesca Esposito, Enzo Tramontano, Pankaj Kumar Singh, Vanna Sanna, Mario Sechi

ACS Med Chem Lett· October 2020

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A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species.
Shuai Hu, Mario Sechi, Pankaj Kumar Singh, Lipeng Dai, Sean McCann

J Med Chem· September 2020

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Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies.
Vanna Sanna, Mario Sechi

ACS Med Chem Lett· June 2020

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Inhibition of Human Immunodeficiency Virus-1 Integrase by β-Diketo Acid Coated Gold Nanoparticles.
Vanna Sanna, Mohamed Fathy Youssef, Nicolino Pala, Dominga Rogolino, Mauro Carcelli, Mario Sechi

ACS Med Chem Lett· May 2020

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Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors.
Francesca Esposito, Mario Sechi, Nicolino Pala, Adele Sanna, Pratibha Chowdary Koneru

Antiviral Res· February 2020

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Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation.
Ahmed T A Boraei, Pankaj K Singh, Mario Sechi, Sandro Satta

Eur J Med Chem· November 2019

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Proproliferative function of adaptor protein GRB10 in prostate carcinoma.
Mohammad Imran Khan, Ahmed Al Johani, Abid Hamid, Bushra Ateeq, Nishat Manzar, Mario Sechi

FASEB J· March 2019

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Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models.
Mario Sechi, Rahul K Lall, Saheed O Afolabi, Anant Singh, Dinesh C Joshi

Sci Rep· October 2018

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Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma.
Yuting Kuang, Mario Sechi, Salvatore Nurra, Mats Ljungman, Nouri Neamati

J Med Chem· February 2018

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Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.
Roberta Cadoni, Nicolino Pala, Carrie Lomelino, Brian P Mahon, Robert McKenna, Mario Sechi

ACS Med Chem Lett· September 2017

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Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy.
Vanna Sanna, Chandra K Singh, Rahime Jashari, Vaqar M Adhami, Jean Christopher Chamcheu, Mario Sechi

Sci Rep· February 2017

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Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.
Jean Christopher Chamcheu, Vaqar M Adhami, Stephane Esnault, Mario Sechi, Imtiaz A Siddiqui

Antioxid Redox Signal· January 2017

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Nanoencapsulation of dietary flavonoid fisetin: Formulation and in vitro antioxidant and α-glucosidase inhibition activities.
Mario Sechi, Deeba N Syed, Nicolino Pala, Alberto Mariani, Salvatore Marceddu

Mater Sci Eng C Mater Biol Appl· November 2016

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Benzoxaborole as a new chemotype for carbonic anhydrase inhibition.
Vincenzo Alterio, Roberta Cadoni, Davide Esposito, Daniela Vullo, Anna Di Fiore, Mario Sechi

Chem Commun (Camb)· September 2016

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N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes.
Mauro Carcelli, Dominga Rogolino, Anna Gatti, Laura De Luca, Mario Sechi

Sci Rep· August 2016

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Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities.
Nicolino Pala, Francesca Esposito, Dominga Rogolino, Mauro Carcelli, Vanna Sanna, Mario Sechi

Int J Mol Sci· August 2016

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