Publications by authors named "Mario Vallon"

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WNT7A/B assemble a GPR124-RECK-LRP5/6 coreceptor complex to activate β-catenin signaling in brain endothelial cells.
Robin Heiden, Laura Hannig, Calvin J Kuo, Süleyman Ergün, Barbara M Braunger, Mario Vallon

J Biol Chem· October 2025

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Protocol for generation of immortalized retinal, choroid, and brain endothelial cell lines.
Laura Hannig, Jakob S Bernhard, Wolfgang Lezuo, Robin Heiden, Mario Vallon

STAR Protoc· September 2025

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Tissue origin of endothelial cells determines immune system modulation and regulation of HIF-1α-, TGF-β-, and VEGF signaling.
Robin Heiden, Laura Hannig, Jakob S Bernhard, Mario Vallon, Anja Schlecht

iScience· February 2025

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GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism.
Kanako Yuki, Mario Vallon, Jie Ding, Cara C Rada, Alan T Tang

Development· June 2024

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Deficiency in Retinal TGFβ Signaling Aggravates Neurodegeneration by Modulating Pro-Apoptotic and MAP Kinase Pathways.
Christina B Bielmeier, Sabrina I Schmitt, Nikolai Kleefeldt, Stefaniya K Boneva, Anja Schlecht, Mario Vallon

Int J Mol Sci· February 2022

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TGFβ-Neurotrophin Interactions in Heart, Retina, and Brain.
Anja Schlecht, Mario Vallon, Nicole Wagner, Süleyman Ergün, Barbara M Braunger

Biomolecules· September 2021

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Transcriptional Profiling Identifies Upregulation of Neuroprotective Pathways in Retinitis Pigmentosa.
Christina B Bielmeier, Saskia Roth, Sabrina I Schmitt, Stefaniya K Boneva, Anja Schlecht, Mario Vallon

Int J Mol Sci· June 2021

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Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.
Yi Miao, Andrew Ha, Wim de Lau, Kanako Yuki, António J M Santos, Mario Vallon

Cell Stem Cell· November 2020

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The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors.
Rory K Morgan, Garret R Anderson, Demet Araç, Gabriela Aust, Nariman Balenga, Mario Vallon

Ann N Y Acad Sci· November 2019

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Receptor subtype discrimination using extensive shape complementary designed interfaces.
Luke T Dang, Yi Miao, Andrew Ha, Kanako Yuki, Keunwan Park, Mario Vallon

Nat Struct Mol Biol· June 2019

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A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability.
Mario Vallon, Kanako Yuki, Thi D Nguyen, Junlei Chang, Jenny Yuan

Cell Rep· October 2018

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Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.
Junlei Chang, Michael R Mancuso, Carolina Maier, Xibin Liang, Kanako Yuki, Mario Vallon

Nat Med· April 2017

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The Wnt7's Tale: A story of an orphan who finds her tie to a famous family.
Makoto Noda, Mario Vallon, Calvin J Kuo

Cancer Sci· May 2016

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International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.
Jörg Hamann, Gabriela Aust, Demet Araç, Felix B Engel, Caroline Formstone, Mario Vallon

Pharmacol Rev· October 2015

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α-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma.
Katharina Teiluf, Christof Seidl, Birgit Blechert, Florian C Gaertner, Klaus-Peter Gilbertz, Mario Vallon

Oncotarget· March 2015

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Developmental and pathological angiogenesis in the central nervous system.
Mario Vallon, Junlei Chang, Haijing Zhang, Calvin J Kuo

Cell Mol Life Sci· September 2014

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A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
Kevin Wei, Stephanie M Piecewicz, Lisa M McGinnis, Cullen M Taniguchi, Stanley J Wiegand, Mario Vallon

Nat Med· October 2013

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Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.
Mario Vallon, Christof Seidl, Birgit Blechert, Zhoulei Li, Klaus-Peter Gilbertz

Eur J Nucl Med Mol Imaging· December 2012

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Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase.
Mario Vallon, Philipp Aubele, Klaus-Peter Janssen, Markus Essler

Biochem J· February 2012

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Tumor endothelial marker 5 expression in endothelial cells during capillary morphogenesis is induced by the small GTPase Rac and mediates contact inhibition of cell proliferation.
Mario Vallon, Franziska Rohde, Klaus-Peter Janssen, Markus Essler

Exp Cell Res· February 2010

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Treatment of peritoneal carcinomatosis by targeted delivery of the radio-labeled tumor homing peptide bi-DTPA-[F3]2 into the nucleus of tumor cells.
Enken Drecoll, Florian C Gaertner, Matthias Miederer, Birgit Blechert, Mario Vallon

PLoS One· May 2009

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Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans.
Mario Vallon, Markus Essler

J Biol Chem· November 2006

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Cellular recognition of tri-/di-palmitoylated peptides is independent from a domain encompassing the N-terminal seven leucine-rich repeat (LRR)/LRR-like motifs of TLR2.
Guangxun Meng, Alina Grabiec, Mario Vallon, Barbara Ebe, Sabrina Hampel

J Biol Chem· October 2003

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