Publications by authors named "Mark A Chaplain"

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A Genuinely Hybrid, Multiscale 3D Cancer Invasion and Metastasis Modelling Framework.
Dimitrios Katsaounis, Nicholas Harbour, Thomas Williams, Mark Aj Chaplain, Nikolaos Sfakianakis

Bull Math Biol· April 2024

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A Multiscale Mathematical Model of Tumour Invasive Growth.
Lu Peng, Dumitru Trucu, Ping Lin, Alastair Thompson, Mark A J Chaplain

Bull Math Biol· March 2017

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Spatio-temporal models of synthetic genetic oscillators.
Cicely K Macnamara, Mark A J Chaplain

Math Biosci Eng· February 2017

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Diffusion driven oscillations in gene regulatory networks.
Cicely K Macnamara, Mark Aj Chaplain

J Theor Biol· October 2016

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Multimodality imaging and mathematical modelling of drug delivery to glioblastomas.
Ahmed Boujelben, Michael Watson, Steven McDougall, Yi-Fen Yen, Elizabeth R Gerstner, Mark A J Chaplain

Interface Focus· October 2016

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Bystander effects and their implications for clinical radiation therapy: Insights from multiscale in silico experiments.
Gibin G Powathil, Alastair J Munro, Mark A J Chaplain, Maciej Swat

J Theor Biol· July 2016

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Mathematical modeling of tumor growth and treatment.
Heiko Enderling, Mark A J Chaplain

Curr Pharm Des· April 2015

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Systems oncology: towards patient-specific treatment regimes informed by multiscale mathematical modelling.
Gibin G Powathil, Maciej Swat, Mark A J Chaplain

Semin Cancer Biol· February 2015

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Multi-scale modelling of the dynamics of cell colonies: insights into cell-adhesion forces and cancer invasion from in silico simulations.
Daniela K Schlüter, Ignacio Ramis-Conde, Mark A J Chaplain

J R Soc Interface· February 2015

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The effect of interstitial pressure on therapeutic agent transport: coupling with the tumor blood and lymphatic vascular systems.
Min Wu, Hermann B Frieboes, Mark A J Chaplain, Steven R McDougall, Vittorio Cristini

J Theor Biol· August 2014

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Stochastic modelling of chromosomal segregation: errors can introduce correction.
Anastasios Matzavinos, Blerta Shtylla, Zachary Voller, Sijia Liu, Mark A J Chaplain

Bull Math Biol· July 2014

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The role of dimerisation and nuclear transport in the Hes1 gene regulatory network.
Marc Sturrock, Andreas Hellander, Sahar Aldakheel, Linda Petzold, Mark A J Chaplain

Bull Math Biol· April 2014

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Towards predicting the response of a solid tumour to chemotherapy and radiotherapy treatments: clinical insights from a computational model.
Gibin G Powathil, Douglas J A Adamson, Mark A J Chaplain

PLoS Comput Biol· February 2014

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Mathematical modeling of cancer invasion: the role of membrane-bound matrix metalloproteinases.
Niall E Deakin, Mark A J Chaplain

Front Oncol· April 2013

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The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems.
Min Wu, Hermann B Frieboes, Steven R McDougall, Mark A J Chaplain, Vittorio Cristini

J Theor Biol· March 2013

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Spatial stochastic modelling of the Hes1 gene regulatory network: intrinsic noise can explain heterogeneity in embryonic stem cell differentiation.
Marc Sturrock, Andreas Hellander, Anastasios Matzavinos, Mark A J Chaplain

J R Soc Interface· March 2013

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Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model.
Gibin G Powathil, Kirsty E Gordon, Lydia A Hill, Mark A J Chaplain

J Theor Biol· September 2012

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Computational modeling of single-cell migration: the leading role of extracellular matrix fibers.
Daniela K Schlüter, Ignacio Ramis-Conde, Mark A J Chaplain

Biophys J· September 2012

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Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling.
Marc Sturrock, Alan J Terry, Dimitris P Xirodimas, Alastair M Thompson, Mark A J Chaplain

Bull Math Biol· July 2012

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Integrating intracellular dynamics using CompuCell3D and Bionetsolver: applications to multiscale modelling of cancer cell growth and invasion.
Vivi Andasari, Ryan T Roper, Maciej H Swat, Mark A J Chaplain

PLoS One· June 2012

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Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors.
Anne L van de Ven, Min Wu, John Lowengrub, Steven R McDougall, Mark A J Chaplain

AIP Adv· March 2012

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Quantifying the role of angiogenesis in malignant progression of gliomas: in silico modeling integrates imaging and histology.
Kristin R Swanson, Russell C Rockne, Jonathan Claridge, Mark A Chaplain, Ellsworth C Alvord

Cancer Res· December 2011

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Spatio-temporal modelling of the NF-κB intracellular signalling pathway: the roles of diffusion, active transport, and cell geometry.
Alan J Terry, Mark A J Chaplain

J Theor Biol· December 2011

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A spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamics.
Alan J Terry, Marc Sturrock, J Kim Dale, Miguel Maroto, Mark A J Chaplain

PLoS One· February 2011

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Physical oncology: a bench-to-bedside quantitative and predictive approach.
Hermann B Frieboes, Mark A J Chaplain, Alastair M Thompson, Elaine L Bearer, John S Lowengrub

Cancer Res· January 2011

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