Publications by authors named "Mark A Cole"

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Hyperpolarized C-MRS can Quantify Lactate Production and Oxidative PDH Flux in Murine Skeletal Muscle During Exercise.
M Kate Curtis, Jordan J McGing, Brianna J Stubbs, Vicky Ball, Lowri E Cochlin, Mark A Cole

NMR Biomed· May 2025

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Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia.
Michal K Handzlik, David J Tooth, Dumitru Constantin-Teodosiu, Paul L Greenhaff, Mark A Cole

Biosci Rep· June 2021

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Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance.
Michal K Handzlik, Dumitru Constantin-Teodosiu, Paul L Greenhaff, Mark A Cole

J Physiol· August 2018

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Novel ketone diet enhances physical and cognitive performance.
Andrew J Murray, Nicholas S Knight, Mark A Cole, Lowri E Cochlin, Emma Carter

FASEB J· December 2016

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On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.
Mark A Cole, Amira H Abd Jamil, Lisa C Heather, Andrew J Murray, Elizabeth R Sutton

FASEB J· August 2016

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Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation.
Latt S Mansor, Keshavi Mehta, Dunja Aksentijevic, Carolyn A Carr, Trine Lund, Mark A Cole

J Physiol· January 2016

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Differential translocation of the fatty acid transporter, FAT/CD36, and the glucose transporter, GLUT4, coordinates changes in cardiac substrate metabolism during ischemia and reperfusion.
Lisa C Heather, Katharine M Pates, Helen J Atherton, Mark A Cole, Daniel R Ball

Circ Heart Fail· September 2013

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Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin.
Latt S Mansor, Eileen R Gonzalez, Mark A Cole, Damian J Tyler, Jessica H Beeson

Cardiovasc Diabetol· September 2013

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Metabolic adaptation to chronic hypoxia in cardiac mitochondria.
Lisa C Heather, Mark A Cole, Jun-Jie Tan, Lucy J A Ambrose, Simon Pope

Basic Res Cardiol· May 2012

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Changes in cardiac substrate transporters and metabolic proteins mirror the metabolic shift in patients with aortic stenosis.
Lisa C Heather, Neil J Howell, Yaso Emmanuel, Mark A Cole, Michael P Frenneaux

PLoS One· February 2012

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First-pass perfusion CMR two days after infarction predicts severity of functional impairment six weeks later in the rat heart.
Daniel J Stuckey, Carolyn A Carr, Stephanie J Meader, Damian J Tyler, Mark A Cole

J Cardiovasc Magn Reson· August 2011

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A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart.
Mark A Cole, Andrew J Murray, Lowri E Cochlin, Lisa C Heather, Sara McAleese

Basic Res Cardiol· May 2011

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Ongoing dual-angle measurements for the correction of partial saturation in 31P MR spectroscopy.
Damian J Tyler, Orlando Lopez, Mark A Cole, Carolyn A Carr, Daniel J Stuckey

Magn Reson Med· October 2010

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Adenosine monophosphate-activated protein kinase activation, substrate transporter translocation, and metabolism in the contracting hyperthyroid rat heart.
Lisa C Heather, Mark A Cole, Helen J Atherton, Will A Coumans, Rhys D Evans

Endocrinology· January 2010

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Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
Marie A Schroeder, Helen J Atherton, Daniel R Ball, Mark A Cole, Lisa C Heather

FASEB J· August 2009

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Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart.
Andrew J Murray, Mark A Cole, Craig A Lygate, Carolyn A Carr, Daniel J Stuckey

J Mol Cell Cardiol· April 2008

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Abnormal function and glucose metabolism in the type-2 diabetic db/db mouse heart.
Marcello Panagia, Jürgen E Schneider, Ben Brown, Mark A Cole, Kieran Clarke

Can J Physiol Pharmacol· October 2007

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Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart.
Lisa C Heather, Mark A Cole, Craig A Lygate, Rhys D Evans, Daniel J Stuckey

Cardiovasc Res· December 2006

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Insulin resistance, abnormal energy metabolism and increased ischemic damage in the chronically infarcted rat heart.
Andrew J Murray, Craig A Lygate, Mark A Cole, Carolyn A Carr, George K Radda

Cardiovasc Res· July 2006

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The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction.
Craig A Lygate, Karen Hulbert, Mina Monfared, Mark A Cole, Kieran Clarke

Cardiovasc Res· June 2003

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Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker Fatty rat heart.
Robert J Sidell, Mark A Cole, Nicholas J Draper, Martine Desrois, Robin E Buckingham

Diabetes· April 2002

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