Publications by authors named "Mark A Perrella"

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PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension.
Rakhshinda Rehman, Paul Dieffenbach, Shamsudheen K Vellarikkal, Alexis M Corcoran, Leilani Pomales, Mark A Perrella

Am J Respir Cell Mol Biol· December 2025

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Therapeutic impact of human trophoblast stem cells in peritoneal and pneumonia-induced sepsis in mice.
Narae Hwang, Gu Li, Ekaterina Murzin, Cassidy J Mays, James A Lederer, Mark A Perrella

Stem Cell Res Ther· July 2025

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Branched-chain ketoacid antioxidants mediate disease tolerance to sepsis.
Aditya Misra, Efi M Weitman, Michal Weitman, Jeannette R Brook, Joseph M Rone, Mark A Perrella

bioRxiv· May 2025

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Stress Granule Assembly in Pulmonary Arterial Hypertension.
Kosmas Kosmas, Aimilia Eirini Papathanasiou, Fotios Spyropoulos, Rakhshinda Rehman, Ashley Anne Cunha, Mark A Perrella

Cells· October 2024

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Carbon monoxide-induced autophagy enhances human mesenchymal stromal cell function via paracrine actions in murine polymicrobial sepsis.
Narae Hwang, Sailaja Ghanta, Qifei Li, Anthony M Lamattina, Ekaterina Murzin, Mark A Perrella

Mol Ther· July 2024

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A metabolomics pipeline highlights microbial metabolism in bloodstream infections.
Jared R Mayers, Jack Varon, Ruixuan R Zhou, Martin Daniel-Ivad, Courtney Beaulieu, Mark A Perrella

Cell· July 2024

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Integrated multi-omics approach reveals the role of striated muscle preferentially expressed protein kinase in skeletal muscle including its relationship with myospryn complex.
Qifei Li, Jasmine Lin, Shiyu Luo, Klaus Schmitz-Abe, Rohan Agrawal, Mark A Perrella

J Cachexia Sarcopenia Muscle· June 2024

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Gasdermin B, an asthma-susceptibility gene, promotes MAVS-TBK1 signalling and airway inflammation.
Tao Liu, Siqi Liu, Xianliang Rui, Ye Cao, Julian Hecker, Mark A Perrella

Eur Respir J· May 2024

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Adult and neonatal models of chemogenetic heart failure caused by oxidative stress.
Fotios Spyropoulos, Apabrita Ayan Das, Markus Waldeck-Weiermair, Shambhu Yadav, Arvind K Pandey, Mark A Perrella

J Clin Invest· March 2024

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Striated preferentially expressed gene deficiency leads to mitochondrial dysfunction in developing cardiomyocytes.
Gu Li, He Huang, Yanshuang Wu, Chang Shu, Narae Hwang, Mark A Perrella

Basic Res Cardiol· February 2024

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Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells.
Julie Ng, Anna E Marneth, Alec Griffith, Daniel Younger, Sailaja Ghanta, Mark A Perrella

J Innate Immun· December 2023

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Identification and targeting of microbial putrescine acetylation in bloodstream infections.
Jared R Mayers, Jack Varon, Ruixuan R Zhou, Martin Daniel-Ivad, Courtney Beaulieu, Mark A Perrella

bioRxiv· September 2023

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Integrated multi-omics approach reveals the role of SPEG in skeletal muscle biology including its relationship with myospryn complex.
Qifei Li, Jasmine Lin, Shiyu Luo, Klaus Schmitz-Abe, Rohan Agrawal, Mark A Perrella

bioRxiv· April 2023

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Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study.
Joshua J Solomon, Sonye K Danoff, Felix A Woodhead, Shelley Hurwitz, Rie Maurer, Mark A Perrella

Lancet Respir Med· January 2023

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Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death.
Shikshya Shrestha, Elio Adib, Jewel Imani, Dean J Aguiar, Anthony M Lamattina, Mark A Perrella

J Biol Chem· November 2022

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Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model.
Qifei Li, Jasmine Lin, Jeffrey J Widrick, Shiyu Luo, Gu Li, Mark A Perrella

JCI Insight· August 2022

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Dysregulated myosin in Hermansky-Pudlak syndrome lung fibroblasts is associated with increased cell motility.
Jewel Imani, Steven P M Bodine, Anthony M Lamattina, Diane D Ma, Shikshya Shrestha, Mark A Perrella

Respir Res· June 2022

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ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells.
Shikshya Shrestha, Anthony Lamattina, Gustavo Pacheco-Rodriguez, Julie Ng, Xiaoli Liu, Mark A Perrella

Life Sci Alliance· May 2022

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Inflammasome activation in neutrophils of patients with severe COVID-19.
Karen Aymonnier, Julie Ng, Laura E Fredenburgh, Katherin Zambrano-Vera, Patrick Münzer, Mark A Perrella

Blood Adv· April 2022

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Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts.
Konstantin Tsoyi, Anthony J Esposito, Bo Sun, Ryan G Bowen, Kevin Xiong, Mark A Perrella

Sci Rep· February 2022

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Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation.
Junwen Han, Yuanyuan Shi, Gareth Willis, Jewel Imani, Min-Young Kwon, Mark A Perrella

FEBS J· January 2022

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Blocking hyaluronan synthesis alleviates acute lung allograft rejection.
Jewel Imani, Kaifeng Liu, Ye Cui, Jean-Pierre Assaker, Junwen Han, Mark A Perrella

JCI Insight· November 2021

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The lung microbiome in end-stage Lymphangioleiomyomatosis.
Julie Ng, Gustavo Pacheco-Rodriguez, Lesa Begley, Yvonne J Huang, Sergio Poli, Mark A Perrella

Respir Res· October 2021

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Induction of Sepsis Via Fibrin Clot Implantation.
Sailaja Ghanta, Min-Young Kwon, Mark A Perrella

Methods Mol Biol· August 2021

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Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice.
Junwen Han, Gu Li, Minmin Hou, Julie Ng, Min-Young Kwon, Mark A Perrella

Stem Cell Res Ther· August 2021

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