Publications by authors named "Mark Biffen"

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Temporal cytokine and lymphoid responses to an inhaled TLR7 antedrug agonist in the cynomolgus monkey demonstrates potential safety and tolerability of this approach.
John Bell, Mike Dymond, Mark Biffen, Stephen Delaney, David Keeling

Toxicol Appl Pharmacol· January 2018

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Tolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848.
Stephen Delaney, Mark Biffen, Justine Maltby, John Bell, Sara Asimus

BMJ Open Respir Res· March 2016

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TLR7 stimulation of APCs results in inhibition of IL-5 through type I IFN and Notch signaling pathways in human peripheral blood mononuclear cells.
Susan Edwards, Carolyn Jones, Andrew J Leishman, Barbara W Young, Hiroyuki Matsui, Mark Biffen

J Immunol· March 2013

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Mechanism of action of inhibition of allergic immune responses by a novel antedrug TLR7 agonist.
Hiroyuki Matsui, Hideyuki Tomizawa, Kazuo Eiho, Yasuo Kashiwazaki, Susan Edwards, Mark Biffen

J Immunol· December 2012

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Haemophilus influenzae induces neutrophil necrosis: a role in chronic obstructive pulmonary disease?
Emma J Naylor, Denise Bakstad, Mark Biffen, Bob Thong, Peter Calverley

Am J Respir Cell Mol Biol· August 2007

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Purification and characterization of recombinant rat mast cell protease 7 expressed in Pichia pastoris.
Carolyn Lawson, Craig Walker, James Awford, Mark Biffen, Philip Mallinder

Protein Expr Purif· July 2002

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