Publications by authors named "Philip Mallinder"

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Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors.
Ani S Balmanoukian, Jeffrey R Infante, Raid Aljumaily, Aung Naing, Ashish V Chintakuntlawar, Philip R Mallinder

Clin Cancer Res· December 2020

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Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Katherine A Vousden, Tomas Lundqvist, Bojana Popovic, Brian Naiman, Alan M Carruthers, Philip R Mallinder

Sci Rep· February 2019

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A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist.
Rebecca Leyland, Amanda Watkins, Kathy A Mulgrew, Nicholas Holoweckyj, Lisa Bamber, Philip Mallinder

Clin Cancer Res· July 2017

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Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease.
Andrew Churg, Caroline V Marshall, Don D Sin, Sarah Bolton, Steven Zhou, Philip R Mallinder

Am J Respir Crit Care Med· January 2012

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Whole-molecule antibody engineering: generation of a high-affinity anti-IL-6 antibody with extended pharmacokinetics.
Donna K Finch, Matthew A Sleeman, Jacques Moisan, Franco Ferraro, Sara Botterell, Philip R Mallinder

J Mol Biol· August 2011

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Engineering a high-affinity anti-IL-15 antibody: crystal structure reveals an α-helix in VH CDR3 as key component of paratope.
David C Lowe, Stefan Gerhardt, Alison Ward, David Hargreaves, Malcolm Anderson, Philip R Mallinder

J Mol Biol· February 2011

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E. coli expression and purification of human and cynomolgus IL-15.
Alison Ward, Malcolm Anderson, Robert I Craggs, Justine Maltby, Caroline Grahames, Philip R Mallinder

Protein Expr Purif· November 2009

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Identification of iNOS inhibitors using InteraX.
Philip R Mallinder, Alan V Wallace, Gary Allenby

J Biomol Screen· March 2009

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Identification of a putative intracellular allosteric antagonist binding-site in the CXC chemokine receptors 1 and 2.
David J Nicholls, Nick P Tomkinson, Katherine E Wiley, Anne Brammall, Lorna Bowers, Philip R Mallinder

Mol Pharmacol· November 2008

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Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Elsa D Garcin, Andrew S Arvai, Robin J Rosenfeld, Matt D Kroeger, Brian R Crane, Philip R Mallinder

Nat Chem Biol· November 2008

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Detection of an activating c-kit mutation by real-time PCR in patients with anaphylaxis.
Wendy Lawley, Heather Hird, Philip Mallinder, Sue McKenna, Beverley Hargadon

Mutat Res· May 2005

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Purification and characterization of recombinant rat mast cell protease 7 expressed in Pichia pastoris.
Carolyn Lawson, Craig Walker, James Awford, Mark Biffen, Philip Mallinder

Protein Expr Purif· July 2002

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