Publications by authors named "Mark Dudley"

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Accelerating progress in immune cell therapy for solid tumours.
Adrian Bot, Mark Dudley, Daniel Shelley, Panagiota A Sotiropoulou

Nat Rev Drug Discov· November 2025

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Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocytes.
Milena Kalaitsidou, Owen R Moon, Martina Sykorova, Leyuan Bao, Yun Qu, Mark E Dudley

Front Immunol· December 2023

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Aerospace Medicine Clinic.
Mark B Dudley

Aerosp Med Hum Perform· July 2023

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Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response.
Qiong Xue, Emily Bettini, Patrick Paczkowski, Colin Ng, Alaina Kaiser, Mark E Dudley

J Immunother Cancer· November 2017

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A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma.
Drew C Deniger, Mei Li M Kwong, Anna Pasetto, Mark E Dudley, John R Wunderlich

Clin Cancer Res· January 2017

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Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Stephanie L Goff, Mark E Dudley, Deborah E Citrin, Robert P Somerville, John R Wunderlich

J Clin Oncol· July 2016

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Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma.
Ling Zhang, Richard A Morgan, Joal D Beane, Zhili Zheng, Mark E Dudley

Clin Cancer Res· May 2015

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Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.
Sanja Stevanović, Lindsey M Draper, Michelle M Langhan, Tracy E Campbell, Mei Li Kwong, Mark E Dudley

J Clin Oncol· May 2015

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A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response.
Paul F Robbins, Sadik H Kassim, Thai L N Tran, Jessica S Crystal, Richard A Morgan, Mark E Dudley

Clin Cancer Res· March 2015

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Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.
James N Kochenderfer, Mark E Dudley, Sadik H Kassim, Robert P T Somerville, Robert O Carpenter

J Clin Oncol· February 2015

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Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans.
Smita S Chandran, Biman C Paria, Abhishek K Srivastava, Luke D Rothermel, Daniel J Stephens, Mark E Dudley

Clin Cancer Res· February 2015

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Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.
Yong-Chen Lu, Xin Yao, Jessica S Crystal, Yong F Li, Mona El-Gamil, Mark E Dudley

Clin Cancer Res· July 2014

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PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors.
Alena Gros, Paul F Robbins, Xin Yao, Yong F Li, Simon Turcotte, Mark E Dudley

J Clin Invest· May 2014

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Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.
Eric Tran, Simon Turcotte, Alena Gros, Paul F Robbins, Yong-Chen Lu, Mark E Dudley

Science· May 2014

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Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation.
James N Kochenderfer, Mark E Dudley, Robert O Carpenter, Sadik H Kassim, Jeremy J Rose

Blood· December 2013

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Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients.
Anna Casati, Azam Varghaei-Nahvi, Steven Alexander Feldman, Mario Assenmacher, Steven Aaron Rosenberg, Mark Edward Dudley

Cancer Immunol Immunother· October 2013

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Phenotype and function of T cells infiltrating visceral metastases from gastrointestinal cancers and melanoma: implications for adoptive cell transfer therapy.
Simon Turcotte, Alena Gros, Katherine Hogan, Eric Tran, Christian S Hinrichs, Mark E Dudley

J Immunol· September 2013

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Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma.
Mark E Dudley, Colin A Gross, Robert P T Somerville, Young Hong, Nicholas P Schaub

J Clin Oncol· June 2013

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Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.
Yong-Chen Lu, Xin Yao, Yong F Li, Mona El-Gamil, Mark E Dudley

J Immunol· June 2013

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Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.
Richard A Morgan, Nachimuthu Chinnasamy, Daniel Abate-Daga, Alena Gros, Paul F Robbins, Mark E Dudley

J Immunother· February 2013

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Bioreactors get personal.
Robert P T Somerville, Mark E Dudley

Oncoimmunology· November 2012

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Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma.
Alena Gros, Simon Turcotte, John R Wunderlich, Mojgan Ahmadzadeh, Mark E Dudley

Clin Cancer Res· October 2012

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A major player "gets in the act".
Mark E Dudley

J Immunother· October 2012

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IRF5 gene polymorphisms in melanoma.
Lorenzo Uccellini, Valeria De Giorgi, Yingdong Zhao, Barbara Tumaini, Narnygerel Erdenebileg, Mark E Dudley

J Transl Med· August 2012

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The stoichiometric production of IL-2 and IFN-γ mRNA defines memory T cells that can self-renew after adoptive transfer in humans.
Anran Wang, Smita Chandran, Syed A Shah, Yu Chiu, Biman C Paria, Mark E Dudley

Sci Transl Med· August 2012

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