Publications by authors named "Mark J Griffiths"

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Metabolic profiling shows pre-existing mitochondrial dysfunction contributes to muscle loss in a model of ICU-acquired weakness.
Paul R Kemp, Richard Paul, Aaron C Hinken, David Neil, Alan Russell, Mark J Griffiths

J Cachexia Sarcopenia Muscle· October 2020

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MicroRNA-542 Promotes Mitochondrial Dysfunction and SMAD Activity and Is Elevated in Intensive Care Unit-acquired Weakness.
Roser Farre Garros, Richard Paul, Martin Connolly, Amy Lewis, Benjamin E Garfield, Mark J Griffiths

Am J Respir Crit Care Med· December 2017

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Deficient retinoid-driven angiogenesis may contribute to failure of adult human lung regeneration in emphysema.
John-Poul Ng-Blichfeldt, Joana Alçada, M Angeles Montero, Charlotte H Dean, Uta Griesenbach, Mark J Griffiths

Thorax· June 2017

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Muscle Regeneration after Critical Illness: Are Satellite Cells the Answer?
Michael I Polkey, Mark J Griffiths, Paul R Kemp

Am J Respir Crit Care Med· October 2016

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The pulmonary endothelium in acute respiratory distress syndrome: insights and therapeutic opportunities.
Fraser R Millar, Charlotte Summers, Mark J Griffiths, Mark R Toshner, Alastair G Proudfoot

Thorax· May 2016

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Mechanical ventilation after lung transplantation.
Louit Thakuria, Rosada Davey, Rosalba Romano, Martin R Carby, Sundeep Kaul, Mark J Griffiths

J Crit Care· February 2016

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Systemic inflammation and oxidative stress post-lung resection: Effect of pretreatment with N-acetylcysteine.
Anthony J Bastin, Nathan Davies, Eric Lim, Greg J Quinlan, Mark J Griffiths

Respirology· January 2016

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The effects of pleural fluid drainage on respiratory function in mechanically ventilated patients after cardiac surgery.
Fraser J H Brims, Michael G Davies, Andy Elia, Mark J D Griffiths

BMJ Open Respir Res· September 2015

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MiR-181a: a potential biomarker of acute muscle wasting following elective high-risk cardiothoracic surgery.
Susannah A A Bloch, Anna V J Donaldson, Amy Lewis, Winston A S Banya, Michael I Polkey, Mark J D Griffiths

Crit Care· April 2015

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Pulmonary venous hypertension and mechanical strain stimulate monocyte chemoattractant protein-1 release and structural remodelling of the lung in human and rodent chronic heart failure models.
John E S Park, Alexander R Lyon, Dongmin Shao, Lauren R Hector, Hua Xu, Mark J D Griffiths

Thorax· December 2014

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Effect of simvastatin on physiological and biological outcomes in patients undergoing esophagectomy: a randomized placebo-controlled trial.
Murali Shyamsundar, Daniel F McAuley, Martin O Shields, Rob MacSweeney, Martin J Duffy, Mark J Griffiths

Ann Surg· January 2014

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Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells.
Sharon Mumby, Latha Ramakrishnan, Timothy W Evans, Mark J D Griffiths, Gregory J Quinlan

Am J Physiol Lung Cell Mol Physiol· January 2014

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Sustained elevation of circulating growth and differentiation factor-15 and a dynamic imbalance in mediators of muscle homeostasis are associated with the development of acute muscle wasting following cardiac surgery.
Susannah A A Bloch, Jen Y Lee, S John Wort, Michael I Polkey, Paul R Kemp, Mark J D Griffiths

Crit Care Med· April 2013

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Strategies to reduce ventilator-associated lung injury (VALI).
David Salman, Simon J Finney, Mark J D Griffiths

Burns· March 2013

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BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.
John E S Park, Dongmin Shao, Paul D Upton, Patricia Desouza, Ian M Adcock, Mark J D Griffiths

PLoS One· July 2012

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Pathophysiology of pulmonary hypertension in acute lung injury.
Laura C Price, Danny F McAuley, Philip S Marino, Simon J Finney, Mark J Griffiths

Am J Physiol Lung Cell Mol Physiol· May 2012

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Influenza-related pneumonia.
Mark H Almond, Danny F McAuley, Matt P Wise, Mark J D Griffiths

Clin Med (Lond)· February 2012

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Biomarkers of acute lung injury: worth their salt?
Alastair G Proudfoot, Matthew Hind, Mark J D Griffiths

BMC Med· December 2011

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Translational research: what does it mean, what has it delivered and what might it deliver?
Alastair G Proudfoot, Danny F McAuley, Matthew Hind, Mark J D Griffiths

Curr Opin Crit Care· October 2011

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Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1).
Moronke A Noah, Giles J Peek, Simon J Finney, Mark J Griffiths, David A Harrison

JAMA· October 2011

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A modified technique for insertion of dual lumen bicaval cannulae for venovenous extracorporeal membrane oxygenation.
Richard H Trimlett, Jeremy J Cordingley, Mark J Griffiths, Susanna Price, David N Hunter

Intensive Care Med· June 2011

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Human models of acute lung injury.
Alastair G Proudfoot, Danny F McAuley, Mark J D Griffiths, Matthew Hind

Dis Model Mech· March 2011

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Biomarkers of lung injury after one-lung ventilation for lung resection.
Anthony J Bastin, Hiroe Sato, Simon J Davidson, Gregory J Quinlan, Mark J Griffiths

Respirology· January 2011

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Small steps in the right direction for ventilator-induced lung injury: Prevention, prevention, prevention!
Mark J D Griffiths, Simon J Finney

Crit Care Med· January 2011

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A stepwise approach to justify phase III randomized clinical trials and enhance the likelihood of a positive result.
Daniel F McAuley, Cecilia O'kane, Mark J D Griffiths

Crit Care Med· October 2010

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