Publications by authors named "Mark Mercer"

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Discovery and Optimization of 4-(8-(3-Fluorophenyl)-1,7-naphthyridin-6-yl)transcyclohexanecarboxylic Acid, an Improved PDE4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease (COPD).
Neil J Press, Roger J Taylor, Joseph D Fullerton, Pamela Tranter, Clive McCarthy, Mark K Mercer

J Med Chem· September 2015

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The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist.
Nicola Arnold, David Beattie, Michelle Bradley, Andrew Brearley, Lyndon Brown, Mark Mercer

Bioorg Med Chem Lett· September 2014

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Solubility-driven optimization of phosphodiesterase-4 inhibitors leading to a clinical candidate.
Neil J Press, Roger J Taylor, Joseph D Fullerton, Pamela Tranter, Clive McCarthy, Mark K Mercer

J Med Chem· September 2012

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A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential.
Neil J Press, Roger J Taylor, Joseph D Fullerton, Pamela Tranter, Clive McCarthy, Mark K Mercer

Bioorg Med Chem Lett· June 2005

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Scaling DNAPL migration from the laboratory to the field.
Paul T Imhoff, Amy S Mann, Mark Mercer, Michael Fitzpatrick

J Contam Hydrol· June 2003

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