Publications by authors named "Mark Smits"

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Once-Monthly Maridebart Cafraglutide in Obesity - A Phase 2 Trial.
Marcel H A Muskiet, Mark M Smits

N Engl J Med· December 2025

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Beyond a singular focus on GLP-1: why we need a new nomenclature now.
Marcel H A Muskiet, Mark M Smits

Lancet Diabetes Endocrinol· September 2025

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The systemic and kidney hemodynamic response to empagliflozin, losartan and their combination varies between individuals.
Britt Eveline Wever, Rosalie Annemien Scholtes, Charlotte Michelle Mosterd, Anne Clasien Hesp, Mark Martinus Smits

J Nephrol· July 2025

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Single incretin receptor knockout mice do not compensate by increasing glucose-stimulated secretion of the remaining incretin hormone.
Katrine D Galsgaard, Jon Vergara, Sara L Jepsen, Alice Bazzichi, Hannelouise Kissow, Mark M Smits

Am J Physiol Endocrinol Metab· March 2025

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Female glucagon receptor knockout mice are prone to steatosis but resistant to weight gain when fed a MASH-promoting GAN diet and a high-fat diet.
Katrine D Galsgaard, Emilie Elmelund, Jenna E Hunt, Mark M Smits, Trisha J Grevengoed

Physiol Rep· February 2025

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Are the lipid-lowering effects of incretin-based therapies relevant for cardiovascular benefit?
Teba Alnima, Mark M Smits, Nordin M J Hanssen

Curr Opin Lipidol· December 2024

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Alpha-cyclodextrin increases glucagon-like peptide-1 secretion in multiple models and improves metabolic status in mice.
Mark M Smits, Liv von Voss, Anna Katarzyna Drzazga, Emily Eufaula Beaman, Annemette Overgaard Brethvad

Food Chem· December 2024

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L-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels.
Ida Marie Modvig, Mark M Smits, Katrine Douglas Galsgaard, Anna Pii Hjørne, Anna Katarzyna Drzazga

Nutr Diabetes· June 2024

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In Vivo Inhibition of Dipeptidyl Peptidase 4 Allows Measurement of GLP-1 Secretion in Mice.
Mark M Smits, Katrine D Galsgaard, Sara Lind Jepsen, Nicolai Wewer Albrechtsen, Bolette Hartmann

Diabetes· May 2024

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Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice.
Mark M Smits, Serafina I L Dreyer, Jenna E Hunt, Anna K Drzazga, Ida M Modvig

Front Endocrinol (Lausanne)· April 2024

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Endogenous glucagon-like peptide (GLP)-1 as alternative for GLP-1 receptor agonists: Could this work and how?
Mark M Smits, Jens J Holst

Diabetes Metab Res Rev· November 2023

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Comment on Bezin et al. GLP-1 Receptor Agonists and the Risk of Thyroid Cancer. Diabetes Care 2023;46:384-390.
Mark M Smits, Daniël H van Raalte

Diabetes Care· May 2023

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Co-sensitization between legumes is frequently seen, but variable and not always clinically relevant.
Mark Smits, Kitty Verhoeckx, André Knulst, Paco Welsing, Aard de Jong

Front Allergy· March 2023

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Mechanisms underlying the blood pressure-lowering effects of empagliflozin, losartan and their combination in people with type 2 diabetes: A secondary analysis of a randomized crossover trial.
Rosalie A Scholtes, Charlotte M Mosterd, Anne C Hesp, Mark M Smits, Hiddo J L Heerspink

Diabetes Obes Metab· January 2023

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Midostaurin as the Most Likely Cause of Bilateral Adrenal Masses in a Patient with Acute Myeloid Leukemia.
Tim Schutte, Claudia A M Stege, Mark M Smits, Laurens E Franssen, Marjolein L Donker

Clin Drug Investig· September 2022

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Association between hypoglycaemic glucose variability and autonomic function in type1 diabetes with impaired hypoglycaemia awareness.
Caterina Racca, Emma J Bouman, Cornelis A J Van Beers, Mark M Smits, Daniel H van Raalte

Diabetes Res Clin Pract· July 2022

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Whole-body insulin clearance in people with type 2 diabetes and normal kidney function: Relationship with glomerular filtration rate, renal plasma flow, and insulin sensitivity.
Michaël J B van Baar, Erik J M van Bommel, Mark M Smits, Daan J Touw, Max Nieuwdorp

J Diabetes Complications· April 2022

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Mechanisms underlying the blood pressure lowering effects of dapagliflozin, exenatide, and their combination in people with type 2 diabetes: a secondary analysis of a randomized trial.
Charlotte C van Ruiten, Mark M Smits, Megan D Kok, Erik H Serné, Daniël H van Raalte

Cardiovasc Diabetol· April 2022

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Kidney hemodynamic profile and systemic vascular function in adults with type 2 diabetes: Analysis of three clinical trials.
Anne C Hesp, Mark M Smits, Erik J M van Bommel, Marcel H A Muskiet, Lennart Tonneijck

J Diabetes Complications· March 2022

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Postprandial renal haemodynamic effects of the dipeptidyl peptidase-4 inhibitor linagliptin versus the sulphonylurea glimepiride in adults with type 2 diabetes (RENALIS): A predefined substudy of a randomized, double-blind trial.
Marcel H A Muskiet, Lennart Tonneijck, Mark M Smits, Mark H H Kramer, D Margriet Ouwens

Diabetes Obes Metab· January 2022

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Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes: data from the COVID-PREDICT cohort study in The Netherlands.
Rick I Meijer, Trynke Hoekstra, Niels C Gritters van den Oever, Suat Simsek, Joop P van den Bergh, Mark M Smits

J Diabetes Metab Disord· December 2021

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Corrigendum: Safety of Semaglutide.
Mark M Smits, Daniël H Van Raalte

Front Endocrinol (Lausanne)· November 2021

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Kidney hemodynamic function in men and postmenopausal women with type 2 diabetes and preserved kidney function.
Daan M van Velzen, Mark M Smits, Erik J M van Bommel, Marcel H A Muskiet, Lennart Tonneijck

Am J Physiol Renal Physiol· June 2021

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The effect of liraglutide and sitagliptin on oxidative stress in persons with type 2 diabetes.
Suvanjaa Sivalingam, Emil List Larsen, Daniel H van Raalte, Marcel H A Muskiet, Mark M Smits

Sci Rep· May 2021

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