Publications by authors named "Mark Wilkes"

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Activation of nemo-like kinase in diamond blackfan anemia suppresses early erythropoiesis by preventing mitochondrial biogenesis.
Mark C Wilkes, Aya Shibuya, Y Lucy Liu, Kailen Mark, Jaqueline Mercado

J Biol Chem· August 2024

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SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction.
Mark C Wilkes, Hee-Don Chae, Vanessa Scanlon, Alma-Martina Cepika, Ethan P Wentworth

Stem Cells· June 2023

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Animal models of Diamond-Blackfan anemia: updates and challenges.
Y Lucy Liu, Aya Shibuya, Bert Glader, Mark C Wilkes, Maria Barna

Haematologica· May 2023

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Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond-Blackfan anemia.
Mark C Wilkes, Vanessa Scanlon, Aya Shibuya, Alma-Martina Cepika, Ascia Eskin

Exp Hematol· July 2022

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Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development.
Mark C Wilkes, Aya Shibuya, Kathleen M Sakamoto

Genes (Basel)· October 2021

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The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond-Blackfan anemia by targeting Nemo-like kinase.
Mark C Wilkes, Kevin Jung, Britney E Lee, Mallika Saxena, Ryan S Sathianathen

J Biol Chem· September 2021

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Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a.
Mark C Wilkes, Kavitha Siva, Gianluca Varetti, Jacqueline Mercado, Ethan P Wentworth

Exp Hematol· November 2020

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MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways.
Minyoung Youn, Haigen Huang, Cheng Chen, Sharon Kam, Mark C Wilkes

Blood Adv· September 2019

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Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia.
Nadia Danilova, Mark Wilkes, Elena Bibikova, Min-Young Youn, Kathleen M Sakamoto

Sci Rep· March 2018

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Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis.
Mark C Wilkes, Claire E Repellin, Kathleen M Sakamoto

Mol Genet Metab· November 2017

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Sorting nexin 9 differentiates ligand-activated Smad3 from Smad2 for nuclear import and transforming growth factor β signaling.
Mark C Wilkes, Claire E Repellin, Jeong-Han Kang, Mahefatiana Andrianifahanana, Xueqian Yin

Mol Biol Cell· November 2015

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Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases.
Mahefatiana Andrianifahanana, Mark C Wilkes, Shiv K Gupta, Rod A Rahimi, Claire E Repellin

FASEB J· November 2013

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Retromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome.
Xueqian Yin, Stephen J Murphy, Mark C Wilkes, Yan Ji, Edward B Leof

Mol Biol Cell· July 2013

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Imatinib mesylate causes genome-wide transcriptional changes in systemic sclerosis fibroblasts in vitro.
Monique Hinchcliff, Chiang-Ching Huang, Wataru Ishida, Feng Fang, Jungwha Lee, Mark Wilkes

Clin Exp Rheumatol· August 2012

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Non-Smad transforming growth factor-β signaling regulated by focal adhesion kinase binding the p85 subunit of phosphatidylinositol 3-kinase.
Min Hong, Mark C Wilkes, Sumedha G Penheiter, Shiv K Gupta, Maryanne Edens

J Biol Chem· May 2011

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Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2.
Sumedha G Penheiter, Raman Deep Singh, Claire E Repellin, Mark C Wilkes, Maryanne Edens

Mol Biol Cell· November 2010

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ERBB receptor activation is required for profibrotic responses to transforming growth factor beta.
Mahefatiana Andrianifahanana, Mark C Wilkes, Claire E Repellin, Maryanne Edens, Theodore J Kottom

Cancer Res· October 2010

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Noncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesis.
Shinong Wang, Mark C Wilkes, Edward B Leof, Raimund Hirschberg

Am J Physiol Renal Physiol· January 2010

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Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.
Mark C Wilkes, Claire E Repellin, Min Hong, Margarita Bracamonte, Sumedha G Penheiter

Dev Cell· March 2009

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Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.
Rod A Rahimi, Mahefatiana Andrianifahanana, Mark C Wilkes, Maryanne Edens, Theodore J Kottom

Cancer Res· January 2009

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Transforming growth factor beta signaling via Ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses.
Kaori Suzuki, Mark C Wilkes, Nandor Garamszegi, Maryanne Edens, Edward B Leof

Cancer Res· April 2007

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Transforming growth factor beta activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures.
Mark C Wilkes, Edward B Leof

J Biol Chem· September 2006

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Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2.
Mark C Wilkes, Hugh Mitchell, Sumedha Gulati Penheiter, Jules J Doré, Kaori Suzuki

Cancer Res· November 2005

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Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo.
Shinong Wang, Mark C Wilkes, Edward B Leof, Raimund Hirschberg

FASEB J· January 2005

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Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis.
Craig E Daniels, Mark C Wilkes, Maryanne Edens, Ted J Kottom, Stephen J Murphy

J Clin Invest· November 2004

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