Publications by authors named "Markus-Frederik Bohn"

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Rational design of antibodies with pH-dependent antigen-binding properties using structural insights from broadly neutralizing antibodies against α-neurotoxins.
Jack Wade, Nina Štrancar, Monica L Fernández-Quintero, Suzana Siebenhaar, Tom Jansen, Markus-Frederik Bohn

MAbs· December 2025

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Antibody Reveals Conformational Latch Controlling Herpesvirus Proteases.
Marcell Zimanyi, Kaitlin R Hulce, Markus-Frederik Bohn, Jordan Norman, Peter J Rohweder

bioRxiv· October 2025

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Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling.
Tulika Tulika, Fulgencio Ruso-Julve, Shirin Ahmadi, Anne Ljungars, Esperanza Rivera-de-Torre, Markus-Frederik Bohn

Structure· September 2024

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A comparative study of protein structure prediction tools for challenging targets: Snake venom toxins.
Konstantinos Kalogeropoulos, Markus-Frederik Bohn, David E Jenkins, Jann Ledergerber, Christoffer V Sørensen

Toxicon· February 2024

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Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library.
Tulika Tulika, Rasmus W Pedersen, Charlotte Rimbault, Shirin Ahmadi, Esperanza Rivera-de-Torre, Markus-Frederik Bohn

Protein Sci· December 2023

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Discovery of a human monoclonal antibody that cross-neutralizes venom phospholipase As from three different snake genera.
Christoffer V Sørensen, José R Almeida, Markus-Frederik Bohn, Esperanza Rivera-de-Torre, Sanne Schoffelen

Toxicon· October 2023

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A single-chain variable fragment selected against a conformational epitope of a recombinantly produced snake toxin using phage display.
Charlotte Rimbault, Pelle D Knudsen, Anna Damsbo, Kim Boddum, Hanif Ali, Markus-Frederik Bohn

N Biotechnol· September 2023

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Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy.
Christoffer V Sørensen, Line Ledsgaard, Helen H K Wildenauer, Camilla H Dahl, Tasja W Ebersole, Markus-Frederik Bohn

Sci Rep· June 2023

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A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy.
Ziyang Zhang, Peter J Rohweder, Chayanid Ongpipattanakul, Koli Basu, Markus-Frederik Bohn

Cancer Cell· September 2022

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Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes.
Jack Wade, Charlotte Rimbault, Hanif Ali, Line Ledsgaard, Esperanza Rivera-de-Torre, Markus-Frederik Bohn

Bioconjug Chem· August 2022

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Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Kaitlin R Hulce, Priyadarshini Jaishankar, Gregory M Lee, Markus-Frederik Bohn, Emily J Connelly

Cell Chem Biol· May 2022

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The challenges with developing therapeutic monoclonal antibodies for pandemic application.
Andreas H Laustsen, Markus-Frederik Bohn, Anne Ljungars

Expert Opin Drug Discov· January 2022

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Immunotargeting of Nanocrystals by SpyCatcher Conjugation of Engineered Antibodies.
Cassio C S Pedroso, Victor R Mann, Kathrin Zuberbühler, Markus-Frederik Bohn, Jessica Yu

ACS Nano· November 2021

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Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope.
Yuval Avnir, Kristina L Prachanronarong, Zhen Zhang, Shurong Hou, Eric C Peterson, Markus-Frederik Bohn

Cell Rep· December 2017

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Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases.
Timothy M Acker, Jonathan E Gable, Markus-Frederik Bohn, Priyadarshini Jaishankar, Michael C Thompson

J Am Chem Soc· August 2017

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Ehlers-Danlos Syndrome Caused by Biallelic TNXB Variants in Patients with Congenital Adrenal Hyperplasia.
Wuyan Chen, Ashley F Perritt, Rachel Morissette, Jennifer L Dreiling, Markus-Frederik Bohn

Hum Mutat· September 2016

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The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Markus-Frederik Bohn, Shivender M D Shandilya, Tania V Silvas, Ellen A Nalivaika, Takahide Kouno

Structure· May 2015

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REdiii: a pipeline for automated structure solution.
Markus Frederik Bohn, Celia A Schiffer

Acta Crystallogr D Biol Crystallogr· May 2015

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A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif.
Shivender M D Shandilya, Markus-Frederik Bohn, Celia A Schiffer

Virology· December 2014

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Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain.
Markus-Frederik Bohn, Shivender M D Shandilya, John S Albin, Takahide Kouno, Brett D Anderson

Structure· June 2013

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Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A.
Michael A Carpenter, Ming Li, Anurag Rathore, Lela Lackey, Emily K Law, Markus-Frederik Bohn

J Biol Chem· October 2012

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