Publications by authors named "Maroof Hasan"

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Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML.
Alberto Risueño, Wendy L See, Iryna Bluemmert, Stéphane de Botton, Courtney D DiNardo, Maroof Hasan

Leuk Res· May 2024

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Enasidenib vs conventional care in older patients with late-stage mutant-IDH2 relapsed/refractory AML: a randomized phase 3 trial.
Stéphane de Botton, Pau Montesinos, Andre C Schuh, Cristina Papayannidis, Paresh Vyas, Maroof Hasan

Blood· January 2023

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Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial.
Courtney D DiNardo, Andre C Schuh, Eytan M Stein, Pau Montesinos, Andrew H Wei, Maroof Hasan

Lancet Oncol· November 2021

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TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis.
Joschka Willemsen, Marie-Therese Neuhoff, Thomas Hoyler, Emma Noir, Clemence Tessier, Maroof Hasan

Cell Rep· November 2021

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Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.
Maroof Hasan, Vijay K Gonugunta, Nicole Dobbs, Aktar Ali, Guillermo Palchik

Proc Natl Acad Sci U S A· January 2017

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TLR9 stability and signaling are regulated by phosphorylation and cell stress.
Maroof Hasan, Erika Gruber, Jody Cameron, Cynthia A Leifer

J Leukoc Biol· September 2016

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Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies.
Maroof Hasan, Nan Yan

Pharmacol Res· September 2016

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Response to Comment on "Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice".
Maroof Hasan, Nan Yan

J Immunol· January 2016

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Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice.
Maroof Hasan, Nicole Dobbs, Shaheen Khan, Michael A White, Edward K Wakeland

J Immunol· November 2015

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Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation.
Maroof Hasan, Charles S Fermaintt, Ningguo Gao, Tomomi Sakai, Takuya Miyazaki

Immunity· September 2015

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Safeguard against DNA sensing: the role of TREX1 in HIV-1 infection and autoimmune diseases.
Maroof Hasan, Nan Yan

Front Microbiol· June 2014

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Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes.
Maroof Hasan, James Koch, Dinesh Rakheja, Asit K Pattnaik, James Brugarolas

Nat Immunol· January 2013

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Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques.
Annette E Sköld, Maroof Hasan, Leonardo Vargas, Hela Saidi, Nathalie Bosquet

Blood· July 2012

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Cutting edge: a TLR9 cytoplasmic tyrosine motif is selectively required for proinflammatory cytokine production.
Annapoorani Chockalingam, William Alfred Rose, Maroof Hasan, Chia-Hsin Ju, Cynthia Anne Leifer

J Immunol· January 2012

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Antimicrobial peptides inhibit polyinosinic-polycytidylic acid-induced immune responses.
Maroof Hasan, Catarina Ruksznis, Yan Wang, Cynthia Anne Leifer

J Immunol· December 2011

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Enhanced induction of HIV-specific cytotoxic T lymphocytes by dendritic cell-targeted delivery of SOCS-1 siRNA.
Sandesh Subramanya, Myriam Armant, Janelle R Salkowitz, Alice M Nyakeriga, Viraga Haridas, Maroof Hasan

Mol Ther· November 2010

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Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice.
Maroof Hasan, Gabriela Lopez-Herrera, K Emelie M Blomberg, Jessica M Lindvall, Anna Berglöf

Immunology· February 2008

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Self-assembling supramolecular complexes by single-stranded extension from plasmid DNA.
Mathias G Svahn, Maroof Hasan, Valeria Sigot, Juan José Valle-Delgado, Mark W Rutland

Oligonucleotides· June 2007

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Increased stability and specificity through combined hybridization of peptide nucleic acid (PNA) and locked nucleic acid (LNA) to supercoiled plasmids for PNA-anchored "Bioplex" formation.
Karin E Lundin, Maroof Hasan, Pedro M Moreno, Elisabeth Törnquist, Iulian Oprea

Biomol Eng· December 2005

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