Publications by authors named "Aktar Ali"

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Hsp90β-Selective Inhibitors: Probing the Solvent-Accessible Frontier.
Terin D'Amico, Michael A Serwetnyk, Xiaozheng Dou, Ian Mersich, Deborah Barlow, Aktar Ali

ChemMedChem· December 2025

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Synergistic Disruption of Survival and Metastatic Potential in Esophageal Adenocarcinoma Cells Through Combined Inhibition of HIF1α and CD73.
Ian Mersich, Alexander Malmberg, Eahsanul Anik, Md Sazzad Hassan, Urs von Holzen, Aktar Ali

Cancers (Basel)· December 2025

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Integrative Multi-Omics Analyses Reveal Mechanisms of Resistance to Hsp90β-Selective Inhibition.
Ian Mersich, Eahsanul Anik, Aktar Ali, Brian S J Blagg

Cancers (Basel)· October 2025

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Genetic insights into vitamin D deficiency: a case-control study of GC and CYP24A1 gene polymorphism.
Usama, Aslam Khan, Muhammad Kashif Raza, Khurram Abbas, Lamjed Mansour, Aktar Ali

Steroids· June 2025

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Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments.
Julian Najera, Hao Chen, Bianca Batista, Frank Ketchum, Aktar Ali

bioRxiv· May 2025

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Investigation of and gene polymorphisms and their association with susceptibility to colorectal cancer.
Durr-E-Shahwar, Hina Zubair, Muhammad Kashif Raza, Zahid Khan, Lamjed Mansour, Aktar Ali

Radiol Oncol· March 2025

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Engineered Age-Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments.
Jun Yang, Lauren Hawthorne, Sharon Stack, Brian Blagg, Aktar Ali

Adv Healthc Mater· March 2025

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Engineered Age-Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments.
Jun Yang, Lauren Hawthorne, Sharon Stack, Brian Blagg, Aktar Ali

bioRxiv· October 2024

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Differential glycosylation in mutant vitamin D-binding protein decimates the binding stability of vitamin D.
Usama, Zahid Khan, Aktar Ali, Masaud Shah, Muhammad Imran

J Biomol Struct Dyn· July 2024

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Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.
Jun Tsunezumi, Hidekazu Sugiura, Lalhaba Oinam, Aktar Ali, Bui Quoc Thang

Matrix Biol· December 2018

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The junior doctor contract 2 years on: one trust's experience of exception reporting.
Christopher J Kirwan, Aktar Ali, Neil McCarten

Br J Hosp Med (Lond)· November 2018

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Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.
Yingfeng Deng, Zhao V Wang, Ruth Gordillo, Yi Zhu, Aktar Ali

Mol Metab· May 2018

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Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.
Maroof Hasan, Vijay K Gonugunta, Nicole Dobbs, Aktar Ali, Guillermo Palchik

Proc Natl Acad Sci U S A· January 2017

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Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.
Gaurab Chakrabarti, Zachary R Moore, Xiuquan Luo, Mariya Ilcheva, Aktar Ali

Cancer Metab· October 2015

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Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation.
Qiong A Wang, Caroline Tao, Lei Jiang, Mengle Shao, Risheng Ye, Aktar Ali

Nat Cell Biol· September 2015

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The estrogen-related receptor α inverse agonist XCT 790 is a nanomolar mitochondrial uncoupler.
Banu Eskiocak, Aktar Ali, Michael A White

Biochemistry· July 2014

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Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.
Zhe Chen, William Holland, John M Shelton, Aktar Ali, Xiaoming Zhan

Proc Natl Acad Sci U S A· May 2014

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Pin1 null mice exhibit low bone mass and attenuation of BMP signaling.
Zhong-Jian Shen, Jie Hu, Aktar Ali, Johanne Pastor, Kazuhiro Shiizaki

PLoS One· December 2013

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SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression.
M Aktar Ali, Aimee Reis, Liang-Hao Ding, Michael D Story, Amyn A Habib

Int J Oncol· April 2009

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The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway.
Seongmi Park, Deepti B Ramnarain, Kimmo J Hatanpaa, Bruce E Mickey, Debabrata Saha, M Aktar Ali

EMBO Rep· August 2008

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SNS-032 prevents tumor cell-induced angiogenesis by inhibiting vascular endothelial growth factor.
M Aktar Ali, Hak Choy, Amyn A Habib, Debabrata Saha

Neoplasia· May 2007

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Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion.
David Zagzag, Yevgeniy Lukyanov, Li Lan, M Aktar Ali, Mine Esencay

Lab Invest· December 2006

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Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: a novel function for an old drug.
Elizabeth W Newcomb, Yevgeniy Lukyanov, Tona Schnee, M Aktar Ali, Li Lan

Int J Oncol· May 2006

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The cyclin-dependent kinase 2 inhibitor down-regulates interleukin-1beta-mediated induction of cyclooxygenase-2 expression in human lung carcinoma cells.
Partha Mukhopadhyay, M Aktar Ali, Animesh Nandi, Peter Carreon, Hak Choy

Cancer Res· February 2006

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Correlation of HER1/EGFR expression and degree of radiosensitizing effect of the HER1/EGFR-tyrosine kinase inhibitor erlotinib.
Jae-Chul Kim, M Aktar Ali, Animesh Nandi, Partha Mukhopadhyay, Hak Choy

Indian J Biochem Biophys· December 2005

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