Publications by authors named "Marta Polak"

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Icotrokinra induces early and sustained pharmacodynamic responses in phase IIb study of patients with moderate-to-severe psoriasis.
David Strawn, James G Krueger, Robert Bissonnette, Kilian Eyerich, Laura K Ferris, Marta E Polak

JCI Insight· December 2025

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Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity.
Anna Appios, James Davies, Sofia Sirvent, Stephen Henderson, Sébastien Trzebanski, Marta E Polak

Sci Immunol· September 2024

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Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis.
Sofia Sirvent, Andres F Vallejo, Emma Corden, Ying Teo, James Davies, Marta E Polak

Nat Commun· May 2023

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Utility and Safety of Skin Tests in Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): A Systematic Review.
Ying Xin Teo, Peter Simon Friedmann, Marta Ewa Polak, Michael Roger Ardern-Jones

J Allergy Clin Immunol Pract· February 2023

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Skin programming of inflammatory responses to Staphylococcus aureus is compartmentalized according to epidermal keratinocyte differentiation status.
Kalum Clayton, Daniel J Holbrook, Andres Vallejo, Gemma Porter, Sofia Sirvent, Marta E Polak

Br J Dermatol· February 2023

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Towards an artificial human lung: modelling organ-like complexity to aid mechanistic understanding.
Maria Victoria Humbert, Cosma Mirella Spalluto, Joseph Bell, Cornelia Blume, Franco Conforti, Marta Polak

Eur Respir J· December 2022

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Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial.
Adam P Dale, Anastasia A Theodosiou, Diane F Gbesemete, Jonathan M Guy, Eleanor F Jones, Marta E Polak

Lancet Microbe· December 2022

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Transcriptional programming of immunoregulatory responses in human Langerhans cells.
James Davies, Sofia Sirvent, Andres F Vallejo, Kalum Clayton, Gemma Douilhet, Marta E Polak

Front Immunol· October 2022

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Blood gene expression predicts intensive care unit admission in hospitalised patients with COVID-19.
Rebekah Penrice-Randal, Xiaofeng Dong, Andrew George Shapanis, Aaron Gardner, Nicholas Harding, Marta E Polak

Front Immunol· October 2022

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Potential Biomarker Identification by RNA-Seq Analysis in Antibiotic-Related Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A Pilot Study.
Ying Xin Teo, Wei Yann Haw, Andreas Vallejo, Carolann McGuire, Jeongmin Woo, Marta Ewa Polak

Toxicol Sci· August 2022

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KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.
Matthew D Blunt, Andres Vallejo Pulido, Jack G Fisher, Lara V Graham, Amber D P Doyle, Marta Polak

J Immunol· July 2022

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Expression Profile of Genes Related to the Th17 Pathway in Macrophages Infected by and : The Use of Gene Regulatory Networks in Modeling This Pathway.
Leilane Oliveira Gonçalves, Andrés F Vallejo Pulido, Fernando Augusto Siqueira Mathias, Alexandre Estevão Silvério Enes, Maria Gabriela Reis Carvalho, Marta E Polak

Front Cell Infect Microbiol· July 2022

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Deleterious Genetic Variation Across the NOD Signaling Pathway Is Associated With Reduced NFKB Signaling Transcription and Upregulation of Alternative Inflammatory Transcripts in Pediatric Inflammatory Bowel Disease.
James J Ashton, Konstantinos Boukas, Imogen S Stafford, Guo Cheng, Rachel Haggarty, Marta E Polak

Inflamm Bowel Dis· June 2022

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Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19.
Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F Vallejo, Stephen Poole, Marta E Polak

Front Immunol· June 2022

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Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages.
Heather C West, James Davies, Stephen Henderson, Oluyori K Adegun, Sophie Ward, Marta E Polak

Cell Rep· May 2022

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Understanding the tuberculosis granuloma: the matrix revolutions.
Paul Elkington, Marta E Polak, Michaela T Reichmann, Alasdair Leslie

Trends Mol Med· February 2022

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An IRF1-IRF4 Toggle-Switch Controls Tolerogenic and Immunogenic Transcriptional Programming in Human Langerhans Cells.
James Davies, Andres F Vallejo, Sofia Sirvent, Gemma Porter, Kalum Clayton, Marta E Polak

Front Immunol· October 2021

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Dual dean entrainment with volume ratio modulation for efficient droplet co-encapsulation: extreme single-cell indexing.
Jack Harrington, Luis Blay Esteban, Jonathan Butement, Andres F Vallejo, Simon I R Lane, Marta E Polak

Lab Chip· September 2021

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Doxycycline host-directed therapy in human pulmonary tuberculosis.
Qing Hao Miow, Andres F Vallejo, Yu Wang, Jia Mei Hong, Chen Bai, Marta E Polak

J Clin Invest· August 2021

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Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.
Michaela T Reichmann, Liku B Tezera, Andres F Vallejo, Milica Vukmirovic, Rui Xiao, Marta E Polak

J Clin Invest· August 2021

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Ileal Transcriptomic Analysis in Paediatric Crohn's Disease Reveals IL17- and NOD-signalling Expression Signatures in Treatment-naïve Patients and Identifies Epithelial Cells Driving Differentially Expressed Genes.
James J Ashton, Konstantinos Boukas, James Davies, Imogen S Stafford, Andres F Vallejo, Marta E Polak

J Crohns Colitis· May 2021

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Tolerogenic and immunogenic states of Langerhans cells are orchestrated by epidermal signals acting on a core maturation gene module.
Marta E Polak, Harinder Singh

Bioessays· May 2021

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Peptide: MHC-based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors.
Pauline Rettman, Matthew D Blunt, Rebecca J Fulton, Andres F Vallejo, Leidy Y Bastidas-Legarda, Marta E Polak

J Immunother Cancer· May 2021

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Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering.
Andres F Vallejo, James Davies, Amit Grover, Ching-Hsuan Tsai, Robert Jepras, Marta E Polak

iScience· March 2021

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Genomic programming of IRF4-expressing human Langerhans cells.
Sofia Sirvent, Andres F Vallejo, James Davies, Kalum Clayton, Zhiguo Wu, Marta E Polak

Nat Commun· January 2020

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