Publications by authors named "Marta Rui"

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Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization.
Giacomo Rossino, Marta Rui, Pasquale Linciano, Daniela Rossi, Massimo Boiocchi

J Med Chem· October 2021

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Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R).
Giacomo Rossino, Marta Rui, Luca Pozzetti, Dirk Schepmann, Bernhard Wünsch

Int J Mol Sci· October 2020

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Exploring the RC-106 Chemical Space: Design and Synthesis of Novel ()-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents.
Roberta Listro, Silvia Stotani, Giacomo Rossino, Marta Rui, Alessio Malacrida

Front Chem· June 2020

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New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative.
Giacomo Rossino, Ivana Orellana, Julio Caballero, Dirk Schepmann, Bernhard Wünsch, Marta Rui

J Chem Inf Model· February 2020

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Dual-Functioning Scaffolds for the Treatment of Spinal Cord Injury: Alginate Nanofibers Loaded with the Sigma 1 Receptor (S1R) Agonist RC-33 in Chitosan Films.
Barbara Vigani, Silvia Rossi, Giuseppina Sandri, Maria Cristina Bonferoni, Marta Rui

Mar Drugs· December 2019

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Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.
Anna Tesei, Michela Cortesi, Sara Pignatta, Chiara Arienti, Giulio Massimo Dondio, Marta Rui

Front Pharmacol· May 2019

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Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.
Marta Rui, Giacomo Rossino, Stefania Coniglio, Stefania Monteleone, Arianna Scuteri

Eur J Med Chem· October 2018

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Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead.
Emanuela Martino, Giuseppe Casamassima, Sonia Castiglione, Edoardo Cellupica, Serena Pantalone, Marta Rui

Bioorg Med Chem Lett· September 2018

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Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer.
Anna Tesei, Michela Cortesi, Alice Zamagni, Chiara Arienti, Sara Pignatta, Marta Rui

Front Pharmacol· July 2018

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A practical guide for using lithium halocarbenoids in homologation reactions.
Serena Monticelli, Marta Rui, Laura Castoldi, Giada Missere, Vittorio Pace

Monatsh Chem· June 2018

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PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds.
Giacomo Rossino, Maria Valeria Raimondi, Marta Rui, Marcello Di Giacomo, Daniela Rossi

Molecules· March 2018

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Approaches for multi-gram scale isolation of enantiomers for drug discovery.
Daniela Rossi, Marilù Tarantino, Giacomo Rossino, Marta Rui, Markus Juza

Expert Opin Drug Discov· December 2017

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Regulation of Aquaporin Functional Properties Mediated by the Antioxidant Effects of Natural Compounds.
Giorgia Pellavio, Marta Rui, Laura Caliogna, Emanuela Martino, Giulia Gastaldi

Int J Mol Sci· December 2017

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Are sigma receptor modulators a weapon against multiple sclerosis disease?
Simona Collina, Marta Rui, Silvia Stotani, Emanuele Bignardi, Daniela Rossi

Future Med Chem· November 2017

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Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones.
Vittorio Pace, Laura Castoldi, Eugenia Mazzeo, Marta Rui, Thierry Langer

Angew Chem Int Ed Engl· October 2017

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Marrubium vulgare L. Leave Extract: Phytochemical Composition, Antioxidant and Wound Healing Properties.
Bédis Amri, Emanuela Martino, Francesca Vitulo, Federica Corana, Leila Bettaieb-Ben Kaâb, Marta Rui

Molecules· October 2017

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Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016).
Simona Collina, Emanuele Bignardi, Marta Rui, Daniela Rossi, Raffaella Gaggeri

Expert Opin Ther Pat· May 2017

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PKC in Regenerative Therapy: New Insights for Old Targets.
Marta Rui, Rita Nasti, Emanuele Bignardi, Serena Della Volpe, Giacomo Rossino

Pharmaceuticals (Basel)· May 2017

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Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines.
Daniela Rossi, Marta Rui, Marcello Di Giacomo, Dirk Schepmann, Bernhard Wünsch

Bioorg Med Chem· January 2017

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Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents.
Marta Rui, Daniela Rossi, Annamaria Marra, Mayra Paolillo, Sergio Schinelli

Eur J Med Chem· November 2016

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The Use of the Comins-Meyers Amide in Synthetic Chemistry: an Overview.
Serena Monticelli, Giovanna Parisi, Marta Rui, Karen de la Vega-Hernández, Irene Murgia

Nat Prod Commun· November 2016

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Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment.
Marta Rui, Annamaria Marra, Vittorio Pace, Markus Juza, Daniela Rossi

Molecules· September 2016

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"Fit-for-purpose" development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel σ1 receptor agonist.
Daniela Rossi, Annamaria Marra, Marta Rui, Stefania Brambilla, Markus Juza

J Pharm Biomed Anal· January 2016

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