Publications by authors named "Martin Bossart"

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Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors.
Amina Khalil, Irina Velikyan, Mengfei Xiong, Martin Bossart, Michael Wagner

EBioMedicine· December 2025

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Photochemical permutation of thiazoles, isothiazoles and other azoles.
Baptiste Roure, Maialen Alonso, Giovanni Lonardi, Dilara Berna Yildiz, Cornelia S Buettner, Martin Bossart

Nature· January 2025

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Introduction of a fatty acid chain modification to prolong circulatory half-life of a radioligand towards glucose-dependent insulinotropic polypeptide receptor.
Amina Khalil, Sona Hakhverdyan, Pierre Cheung, Martin Bossart, Michael Wagner

Nucl Med Biol· February 2024

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European Medicinal Chemistry Leaders in Industry (EMCL) - On the Status and Future of Medicinal Chemistry Research in Europe.
Amjad Ali, Marcus Bauser, Sophie Bertrand, Wesley Blackaby, Christoph Boss, Martin Bossart

ChemMedChem· July 2023

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Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences.
Irina Velikyan, Martin Bossart, Torsten Haack, Iina Laitinen, Sergio Estrada

Pharmaceuticals (Basel)· December 2022

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Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Iina Laitinen

J Nucl Med· May 2022

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Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist.
Martin Bossart, Michael Wagner, Ralf Elvert, Andreas Evers, Thomas Hübschle

Cell Metab· January 2022

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Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Iina Laitinen

J Nucl Med· June 2021

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Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers

Diabetes· April 2021

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Incretin combination therapy for the treatment of non-alcoholic steatohepatitis.
Aimo Kannt, Andreas Nygaard Madsen, Claire Kammermeier, Ralf Elvert, Tim Klöckener, Martin Bossart

Diabetes Obes Metab· August 2020

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Automated GMP-Compliant Production of [Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans.
Michael Wagner, Johan G Doverfjord, Joachim Tillner, Gunnar Antoni, Torsten Haack, Martin Bossart

Pharmaceuticals (Basel)· July 2020

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Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers

Sci Rep· October 2019

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The preprohormone expression profile of enteroendocrine cells following Roux-en-Y gastric bypass in rats.
Chen Zhang, Kristoffer Rigbolt, Søren Ljungberg Petersen, Lise Christine Biehl Rudkjær, Uwe Schwahn, Martin Bossart

Peptides· August 2019

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Peptide Optimization at the Drug Discovery-Development Interface: Tailoring of Physicochemical Properties Toward Specific Formulation Requirements.
Andreas Evers, Stefania Pfeiffer-Marek, Martin Bossart, Christoph Heubel, Ursula Stock

J Pharm Sci· April 2019

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First-in-class positron emission tomography tracer for the glucagon receptor.
Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers, Iina Laitinen

EJNMMI Res· February 2019

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A novel dual glucagon-like peptide and glucagon receptor agonist SAR425899: Results of randomized, placebo-controlled first-in-human and first-in-patient trials.
Joachim Tillner, Maximilian G Posch, Frank Wagner, Lenore Teichert, Youssef Hijazi, Martin Bossart

Diabetes Obes Metab· January 2019

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Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates.
Ralf Elvert, Andreas W Herling, Martin Bossart, Tilo Weiss, Baohong Zhang

Diabetes Obes Metab· August 2018

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Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys.
Ralf Elvert, Martin Bossart, Andreas W Herling, Tilo Weiss, Baohong Zhang

Endocrinology· August 2018

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Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
Andreas Evers, Martin Bossart, Stefania Pfeiffer-Marek, Ralf Elvert, Herman Schreuder

J Med Chem· July 2018

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Correction to Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonist.
Andreas Evers, Torsten Haack, Martin Lorenz, Martin Bossart, Ralf Elvert

J Med Chem· July 2017

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Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists.
Andreas Evers, Torsten Haack, Martin Lorenz, Martin Bossart, Ralf Elvert

J Med Chem· May 2017

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Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment.
Masaki Handa, Karl A Scheidt, Martin Bossart, Nan Zheng, William R Roush

J Org Chem· February 2008

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