Publications by authors named "Torsten Haack"

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Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences.
Irina Velikyan, Martin Bossart, Torsten Haack, Iina Laitinen, Sergio Estrada

Pharmaceuticals (Basel)· December 2022

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Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Iina Laitinen

J Nucl Med· May 2022

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Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Iina Laitinen

J Nucl Med· June 2021

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Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers

Diabetes· April 2021

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Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes.
Olof Eriksson, Torsten Haack, Youssef Hijazi, Lenore Teichert, Veronique Tavernier

Sci Rep· October 2020

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Incretin combination therapy for the treatment of non-alcoholic steatohepatitis.
Aimo Kannt, Andreas Nygaard Madsen, Claire Kammermeier, Ralf Elvert, Tim Klöckener, Torsten Haack

Diabetes Obes Metab· August 2020

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Automated GMP-Compliant Production of [Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans.
Michael Wagner, Johan G Doverfjord, Joachim Tillner, Gunnar Antoni, Torsten Haack

Pharmaceuticals (Basel)· July 2020

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Self-Assembly of Exendin-4-Derived Dual Peptide Agonists is Mediated by Acylation and Correlated to the Length of Conjugated Fatty Acyl Chains.
Martin Wolff, Anja Schüler, Klaus Gast, Robert Seckler, Andreas Evers, Torsten Haack

Mol Pharm· March 2020

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Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers

Sci Rep· October 2019

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First-in-class positron emission tomography tracer for the glucagon receptor.
Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers, Iina Laitinen

EJNMMI Res· February 2019

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A novel dual glucagon-like peptide and glucagon receptor agonist SAR425899: Results of randomized, placebo-controlled first-in-human and first-in-patient trials.
Joachim Tillner, Maximilian G Posch, Frank Wagner, Lenore Teichert, Youssef Hijazi, Torsten Haack

Diabetes Obes Metab· January 2019

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Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates.
Ralf Elvert, Andreas W Herling, Martin Bossart, Tilo Weiss, Baohong Zhang, Torsten Haack

Diabetes Obes Metab· August 2018

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Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys.
Ralf Elvert, Martin Bossart, Andreas W Herling, Tilo Weiss, Baohong Zhang, Torsten Haack

Endocrinology· August 2018

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Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
Andreas Evers, Martin Bossart, Stefania Pfeiffer-Marek, Ralf Elvert, Herman Schreuder, Torsten Haack

J Med Chem· July 2018

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Correction to Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonist.
Andreas Evers, Torsten Haack, Martin Lorenz, Martin Bossart, Ralf Elvert

J Med Chem· July 2017

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Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists.
Andreas Evers, Torsten Haack, Martin Lorenz, Martin Bossart, Ralf Elvert

J Med Chem· May 2017

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Oral delivery of diabetes peptides - Comparing standard formulations incorporating functional excipients and nanotechnologies in the translational context.
Harivardhan Reddy Lakkireddy, Matthias Urmann, Melissa Besenius, Ulrich Werner, Torsten Haack

Adv Drug Deliv Rev· November 2016

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1,1-Dioxo-5,6-dihydro-[4,1,2]oxathiazines, a novel class of 11ß-HSD1 inhibitors for the treatment of diabetes.
Thomas Böhme, Christian K Engel, Géraldine Farjot, Stefan Güssregen, Torsten Haack

Bioorg Med Chem Lett· August 2013

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Synthesis of oximidine II by a copper-mediated reductive ene-yne macrocyclization.
Christopher M Schneider, Kriangsak Khownium, Wei Li, Jared T Spletstoser, Torsten Haack

Angew Chem Int Ed Engl· August 2011

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Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036.
Wayne W Chan, Scott C Wise, Michael D Kaufman, Yu Mi Ahn, Carol L Ensinger, Torsten Haack

Cancer Cell· April 2011

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Synthesis of a quinolone library from ynones.
Timothy R Ward, Brandon J Turunen, Torsten Haack, Benjamin Neuenswander, William Shadrick

Tetrahedron Lett· November 2009

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Further exploration of antimicrobial ketodihydronicotinic acid derivatives by multiple parallel syntheses.
Jane B Laursen, John Nielsen, Torsten Haack, Srinivas Pusuluri, Sunil David

Comb Chem High Throughput Screen· November 2006

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Formal total syntheses of the (-)-salicylihalamides A and B from D-glucose and L-rhamnose.
Torsten Haack, KyoungLang Haack, Wibke E Diederich, Burchelle Blackman, Subho Roy

J Org Chem· September 2005

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Synthesis, characterization, and 32P-postlabeling of N-(deoxyguanosin)-4-aminobiphenyl 3'-phosphate adducts.
Torsten Haack, Gernot Boche, Christian Kliem, Manfred Wiessler, Dieter Albert

Chem Res Toxicol· June 2004

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Studies toward the synthesis of oximidines I and II.
Torsten Haack, Serdar Kurtkaya, James P Snyder, Gunda I Georg

Org Lett· December 2003

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