Publications by authors named "Martin Gellert"

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How RAG1/2 evolved from ancestral transposases to initiate V(D)J recombination without transposition.
Xuemin Chen, Liangrui Yao, Wenwen Li, Shanshan Ma, Xingyun Yuan, Martin Gellert

Proc Natl Acad Sci U S A· August 2025

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Dynamic assemblies and coordinated reactions of non-homologous end joining.
Lan Liu, Jun Li, Metztli Cisneros-Aguirre, Arianna Merkell, Jeremy M Stark, Martin Gellert

Nature· July 2025

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How RAG1/2 evolved from ancestral transposases to initiate V(D)J recombination without transposition.
Xuemin Chen, Liangrui Yao, Shanshan Ma, Xingyun Yuan, Yang Yang, Martin Gellert

Res Sq· February 2025

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Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining.
Christopher J Buehl, Noah J Goff, Steven W Hardwick, Martin Gellert, Tom L Blundell

Mol Cell· March 2023

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Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Lan Liu, Xuemin Chen, Jun Li, Huaibin Wang, Christopher J Buehl, Martin Gellert

Mol Cell· January 2022

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Inner workings of RAG recombinase and its specialization for adaptive immunity.
Xuemin Chen, Martin Gellert, Wei Yang

Curr Opin Struct Biol· December 2021

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Structure of an activated DNA-PK and its implications for NHEJ.
Xuemin Chen, Xiang Xu, Yun Chen, Joyce C Cheung, Huaibin Wang, Martin Gellert

Mol Cell· February 2021

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Cutting antiparallel DNA strands in a single active site.
Xuemin Chen, Yanxiang Cui, Robert B Best, Huaibin Wang, Z Hong Zhou, Martin Gellert

Nat Struct Mol Biol· February 2020

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How mouse RAG recombinase avoids DNA transposition.
Xuemin Chen, Yanxiang Cui, Huaibin Wang, Z Hong Zhou, Martin Gellert

Nat Struct Mol Biol· February 2020

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Cracking the DNA Code for V(D)J Recombination.
Min-Sung Kim, Watchalee Chuenchor, Xuemin Chen, Yanxiang Cui, Xing Zhang, Martin Gellert

Mol Cell· April 2018

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Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes.
Lisa Ott de Bruin, Wei Yang, Kelly Capuder, Yu Nee Lee, Maddalena Antolini, Martin Gellert

Oncotarget· March 2016

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Role of RAG1 autoubiquitination in V(D)J recombination.
Samarendra K Singh, Martin Gellert

Proc Natl Acad Sci U S A· July 2015

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Assembly Pathway and Characterization of the RAG1/2-DNA Paired and Signal-end Complexes.
Mikalai Lapkouski, Watchalee Chuenchor, Min-Sung Kim, Martin Gellert, Wei Yang

J Biol Chem· June 2015

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Crystal structure of the V(D)J recombinase RAG1-RAG2.
Min-Sung Kim, Mikalai Lapkouski, Wei Yang, Martin Gellert

Nature· February 2015

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Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.
Jee-Hyun Um, Alexandra L Brown, Samarendra K Singh, Yong Chen, Marjan Gucek, Martin Gellert

Proc Natl Acad Sci U S A· June 2013

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High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.
Sandeep Dayal, Jakub Nedbal, Philip Hobson, Alison M Cooper, Hannah J Gould, Martin Gellert

PLoS One· February 2012

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Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops.
Shikha Gupta, Martin Gellert, Wei Yang

Nat Struct Mol Biol· December 2011

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Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination.
Gabrielle J Grundy, Wei Yang, Martin Gellert

Proc Natl Acad Sci U S A· December 2010

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Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex.
Gabrielle J Grundy, Santiago Ramón-Maiques, Emilios K Dimitriadis, Svetlana Kotova, Christian Biertümpfel, Martin Gellert

Mol Cell· July 2009

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An activation-induced cytidine deaminase-independent mechanism of secondary VH gene rearrangement in preimmune human B cells.
Nancy S Longo, Gabrielle J Grundy, Jisoo Lee, Martin Gellert, Peter E Lipsky

J Immunol· December 2008

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Requirements for DNA hairpin formation by RAG1/2.
Gabrielle J Grundy, Joanne E Hesse, Martin Gellert

Proc Natl Acad Sci U S A· February 2007

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DNA repair: from molecular mechanism to human disease.
Errol C Friedberg, Andres Aguilera, Martin Gellert, Philip C Hanawalt, John B Hays

DNA Repair (Amst)· August 2006

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The taming of a transposon: V(D)J recombination and the immune system.
Jessica M Jones, Martin Gellert

Immunol Rev· August 2004

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Autoubiquitylation of the V(D)J recombinase protein RAG1.
Jessica M Jones, Martin Gellert

Proc Natl Acad Sci U S A· December 2003

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Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive.
Mauro Modesti, Murray S Junop, Rodolfo Ghirlando, Mandy van de Rakt, Martin Gellert

J Mol Biol· November 2003

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