Publications by authors named "Nancy S Longo"

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Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Cinque Soto, Gilad Ofek, M Gordon Joyce, Baoshan Zhang, Krisha McKee, Nancy S Longo

PLoS One· July 2017

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Mechanisms That Shape Human Antibody Repertoire Development in Mice Transgenic for Human Ig H and L Chain Loci.
Nancy S Longo, Tobias Rogosch, Michael Zemlin, Moncef Zouali, Peter E Lipsky

J Immunol· May 2017

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Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding.
Nancy S Longo, Matthew S Sutton, Andrea R Shiakolas, Javier Guenaga, Marissa C Jarosinski

J Virol· December 2016

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Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Tongqing Zhou, Rebecca M Lynch, Lei Chen, Priyamvada Acharya, Xueling Wu, Nancy S Longo

Cell· June 2015

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HTJoinSolver: Human immunoglobulin VDJ partitioning using approximate dynamic programming constrained by conserved motifs.
Daniel E Russ, Kwan-Yuet Ho, Nancy S Longo

BMC Bioinformatics· May 2015

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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Xueling Wu, Zhenhai Zhang, Chaim A Schramm, M Gordon Joyce, Young Do Kwon, Nancy S Longo

Cell· April 2015

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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nicole A Doria-Rose, Chaim A Schramm, Jason Gorman, Penny L Moore, Jinal N Bhiman, Nancy S Longo

Nature· May 2014

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Isolation of human monoclonal antibodies from peripheral blood B cells.
Jinghe Huang, Nicole A Doria-Rose, Nancy S Longo, Leo Laub, Chien-Li Lin

Nat Protoc· October 2013

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Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies.
Tongqing Zhou, Jiang Zhu, Xueling Wu, Stephanie Moquin, Baoshan Zhang, Nancy S Longo

Immunity· August 2013

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.
Jinghe Huang, Gilad Ofek, Leo Laub, Mark K Louder, Nicole A Doria-Rose, Nancy S Longo

Nature· November 2012

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HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins.
Yuxing Li, Sijy O'Dell, Richard Wilson, Xueling Wu, Stephen D Schmidt, Nancy S Longo

J Virol· October 2012

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Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Xueling Wu, Tongqing Zhou, Jiang Zhu, Baoshan Zhang, Ivelin Georgiev, Nancy S Longo

Science· September 2011

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Comparison of antibody repertoires produced by HIV-1 infection, other chronic and acute infections, and systemic autoimmune disease.
Felix Breden, Christa Lepik, Nancy S Longo, Marinieve Montero, Peter E Lipsky

PLoS One· March 2011

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
Xueling Wu, Zhi-Yong Yang, Yuxing Li, Carl-Magnus Hogerkorp, William R Schief, Nancy S Longo

Science· August 2010

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Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens.
Xiaodong Xiao, Weizao Chen, Yang Feng, Zhongyu Zhu, Ponraj Prabakaran, Nancy S Longo

Biochem Biophys Res Commun· December 2009

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Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.
Nancy S Longo, Patricia L Lugar, Sule Yavuz, Wen Zhang, Peter H L Krijger

Blood· April 2009

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An activation-induced cytidine deaminase-independent mechanism of secondary VH gene rearrangement in preimmune human B cells.
Nancy S Longo, Gabrielle J Grundy, Jisoo Lee, Martin Gellert, Peter E Lipsky

J Immunol· December 2008

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Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase.
Nancy S Longo, Colleen L Satorius, Alessandro Plebani, Anne Durandy, Peter E Lipsky

J Immunol· July 2008

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Effective therapy for nephritis in (NZB x NZW)F1 mice with triptolide and tripdiolide, the principal active components of the Chinese herbal remedy Tripterygium wilfordii Hook F.
Xuelian Tao, Fred Fan, Victoria Hoffmann, Chun Y Gao, Nancy S Longo

Arthritis Rheum· June 2008

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The NF-kappaB canonical pathway is involved in the control of the exonucleolytic processing of coding ends during V(D)J recombination.
M Margarida Souto-Carneiro, Ruth Fritsch, Nuno Sepúlveda, M João Lagareiro, Nuno Morgado, Nancy S Longo

J Immunol· January 2008

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B-cell repertoire and clonal analysis in unaffected first degree relatives in familial chronic lymphocytic leukaemia kindred.
Fatima Abbasi, Nancy S Longo, Peter E Lipsky, Elizabeth Raveche, Therese A Schleinitz

Br J Haematol· December 2007

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Why do B cells mutate their immunoglobulin receptors?
Nancy S Longo, Peter E Lipsky

Trends Immunol· August 2006

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Therapeutic impact of the ethyl acetate extract of Tripterygium wilfordii Hook F on nephritis in NZB/W F1 mice.
Xuelian Tao, Fred Fan, Victoria Hoffmann, Nancy S Longo, Peter E Lipsky

Arthritis Res Ther· July 2006

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Staphylococcal protein a deletes B-1a and marginal zone B lymphocytes expressing human immunoglobulins: an immune evasion mechanism.
Muriel Viau, Nancy S Longo, Peter E Lipsky, Moncef Zouali

J Immunol· December 2005

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Specific in vivo deletion of B-cell subpopulations expressing human immunoglobulins by the B-cell superantigen protein L.
Muriel Viau, Nancy S Longo, Peter E Lipsky, Lars Björck, Moncef Zouali

Infect Immun· June 2004

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