Publications by authors named "Gilad Ofek"

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Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Wilton B Williams, S Munir Alam, Gilad Ofek, Nathaniel Erdmann, David C Montefiori

Cell· November 2025

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Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design.
Linling He, Yi-Zong Lee, Yi-Nan Zhang, Maddy L Newby, Benjamin M Janus, Gilad Ofek

bioRxiv· May 2025

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Macaque antibodies targeting Marburg virus glycoprotein induced by multivalent immunization.
Benjamin M Janus, Ruixue Wang, Thomas E Cleveland, Matthew C Metcalf, Aaron C Lemmer, Gilad Ofek

J Virol· July 2024

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Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Wilton B Williams, S Munir Alam, Gilad Ofek, Nathaniel Erdmann, David C Montefiori

Cell· June 2024

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Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development.
Brian G Pierce, Nathaniel Felbinger, Matthew Metcalf, Eric A Toth, Gilad Ofek

Viruses· May 2024

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Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies.
Matthew C Metcalf, Benjamin M Janus, Rui Yin, Ruixue Wang, Johnathan D Guest, Gilad Ofek

Nat Commun· July 2023

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Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge.
Andrey Romanyuk, Ruixue Wang, Alexander Marin, Benjamin M Janus, Eric I Felner, Gilad Ofek

J Funct Biomater· December 2022

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Structural Features of Antibody-Peptide Recognition.
Jessica H Lee, Rui Yin, Gilad Ofek, Brian G Pierce

Front Immunol· July 2022

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HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
David Easterhoff, Justin Pollara, Kan Luo, Benjamin Janus, Neelakshi Gohain, Gilad Ofek

JCI Insight· January 2020

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Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop.
Benjamin M Janus, Nydia van Dyk, Xuelian Zhao, Katie A Howell, Cinque Soto, Gilad Ofek

Nat Commun· September 2018

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Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Cinque Soto, Gilad Ofek, M Gordon Joyce, Baoshan Zhang, Krisha McKee

PLoS One· July 2017

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Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
LaTonya D Williams, Gilad Ofek, Sebastian Schätzle, Jonathan R McDaniel, Xiaozhi Lu

Sci Immunol· January 2017

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Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
Young D Kwon, Ivelin S Georgiev, Gilad Ofek, Baoshan Zhang, Mangaiarkarasi Asokan

J Virol· July 2016

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Transplanting supersites of HIV-1 vulnerability.
Tongqing Zhou, Jiang Zhu, Yongping Yang, Jason Gorman, Gilad Ofek

PLoS One· November 2015

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Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.
Young Do Kwon, Marie Pancera, Priyamvada Acharya, Ivelin S Georgiev, Emma T Crooks, Gilad Ofek

Nat Struct Mol Biol· July 2015

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Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Gregory H Bird, Adriana Irimia, Gilad Ofek, Peter D Kwong, Ian A Wilson

Nat Struct Mol Biol· December 2014

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HIV. Expanding the breadth of an HIV-1 vaccine.
Gilad Ofek, Ron Diskin

Science· December 2014

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Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
Marie Pancera, Tongqing Zhou, Aliaksandr Druz, Ivelin S Georgiev, Cinque Soto, Gilad Ofek

Nature· October 2014

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Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6.
Gilad Ofek, Brett Zirkle, Yongping Yang, Zhongyu Zhu, Krisha McKee

J Virol· March 2014

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Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline.
Ivelin S Georgiev, Rebecca S Rudicell, Kevin O Saunders, Wei Shi, Tatsiana Kirys, Gilad Ofek

J Immunol· February 2014

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Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Ivelin S Georgiev, Nicole A Doria-Rose, Tongqing Zhou, Young Do Kwon, Ryan P Staupe, Gilad Ofek

Science· May 2013

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Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains.
Jiang Zhu, Gilad Ofek, Yongping Yang, Baoshan Zhang, Mark K Louder

Proc Natl Acad Sci U S A· April 2013

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.
Jinghe Huang, Gilad Ofek, Leo Laub, Mark K Louder, Nicole A Doria-Rose

Nature· November 2012

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Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics.
Jiang Zhu, Sijy O'Dell, Gilad Ofek, Marie Pancera, Xueling Wu

Front Microbiol· October 2012

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Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.
S Moses Dennison, Laura L Sutherland, Frederick H Jaeger, Kara M Anasti, Robert Parks, Gilad Ofek

PLoS One· April 2012

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