Publications by authors named "Wilton B Williams"

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Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Wilton B Williams, S Munir Alam, Gilad Ofek, Nathaniel Erdmann, David C Montefiori

Cell· November 2025

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Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development.
Rumi Habib, Ryan S Roark, Hui Li, Andrew Jesse Connell, Michael P Hogarty, Wilton B Williams

bioRxiv· September 2025

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An HIV-1 gp41 peptide-liposome vaccine elicits neutralizing epitope-targeted antibody responses in healthy individuals.
Nathaniel Erdmann, Wilton B Williams, Stephen R Walsh, Derek W Cain, Matthew Clark

medRxiv· August 2025

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Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Qingbo Liu, Ruth J Parsons, Kevin Wiehe, Robert J Edwards, Kevin O Saunders, Wilton B Williams

Structure· August 2025

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Optimizing human B cell repertoire analyses to interpret clinical data and design sequential HIV vaccines.
Milton Maciel, Lindsey R Baden, Brian Briney, Nicole A Doria-Rose, Kasalina N Kiwanuka, Wilton B Williams

NPJ Vaccines· July 2025

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Safety and implementation of phase I randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns.
Avy Violari, Kennedy Otwombe, William Hahn, Shiyu Chen, Deirdre Josipovic, Wilton B Williams

J Clin Invest· June 2025

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Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques.
Sommer Holmes, Hui Li, Xiaoying Shen, Mitchell Martin, Ryan Tuck, Wilton B Williams

Nat Commun· November 2024

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Safety and implementation of a phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns.
Avy Violari, Kennedy Otwombe, William Hahn, Shiyu Chen, Deirdre Josipovic, Wilton B Williams

medRxiv· October 2024

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Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques.
Ashley N Nelson, Xiaoying Shen, Sravani Vekatayogi, Shiyu Zhang, Gabriel Ozorowski, Wilton B Williams

Sci Immunol· August 2024

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SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.
Qianyi E Zhang, Jared Lindenberger, Ruth J Parsons, Bhishem Thakur, Rob Parks, Wilton B Williams

Mol Cell· July 2024

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Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Wilton B Williams, S Munir Alam, Gilad Ofek, Nathaniel Erdmann, David C Montefiori

Cell· June 2024

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Viral Envelope Evolution in Simian-HIV-Infected Neonate and Adult-Dam Pairs of Rhesus Macaques.
Elena E Giorgi, Hui Li, Bhavna Hora, George M Shaw, Kshitij Wagh, Wilton B Williams

Viruses· June 2024

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Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction.
Kevin Wiehe, Kevin O Saunders, Victoria Stalls, Derek W Cain, Sravani Venkatayogi, Wilton B Williams

Cell Host Microbe· May 2024

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SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.
Qianyi E Zhang, Jared Lindenberger, Ruth Parsons, Bhishem Thakur, Rob Parks, Wilton B Williams

bioRxiv· March 2024

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Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques.
Kevin O Saunders, James Counts, Bhishem Thakur, Victoria Stalls, Robert Edwards, Wilton B Williams

Cell· January 2024

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Host immunity associated with spontaneous suppression of viremia in therapy-naïve young rhesus macaques following neonatal SHIV infection.
Tyler D Evangelous, Madison Berry, Sravani Venkatayogi, Cas LeMaster, Eric S Geanes, Wilton B Williams

J Virol· November 2023

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Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.
Ashley N Nelson, Xiaoying Shen, Sravani Vekatayogi, Shiyu Zhang, Gabriel Ozorowski, Wilton B Williams

bioRxiv· November 2023

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Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies.
Bhavna Hora, Hui Li, Xiaoying Shen, Mitchell Martin, Yue Chen, Wilton B Williams

Cell Rep· March 2023

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Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.
Kevin O Saunders, Robert J Edwards, Kedamawit Tilahun, Kartik Manne, Xiaozhi Lu, Wilton B Williams

Sci Transl Med· September 2022

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Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike.
Victoria Stalls, Jared Lindenberger, Sophie M-C Gobeil, Rory Henderson, Rob Parks, Wilton B Williams

Cell Rep· June 2022

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mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice.
Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Wilton B Williams

Cell Rep· March 2022

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Strategies for induction of HIV-1 envelope-reactive broadly neutralizing antibodies.
Wilton B Williams, Kevin Wiehe, Kevin O Saunders, Barton F Haynes

J Int AIDS Soc· November 2021

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Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles.
Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Wilton B Williams

bioRxiv· August 2021

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Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Wilton B Williams, R Ryan Meyerhoff, R J Edwards, Hui Li, Kartik Manne

Cell· May 2021

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Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.
Ryan S Roark, Hui Li, Wilton B Williams, Hema Chug, Rosemarie D Mason

Science· January 2021

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