Publications by authors named "David Easterhoff"

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Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Qingbo Liu, Ruth J Parsons, Kevin Wiehe, Robert J Edwards, Kevin O Saunders, David Easterhoff

Structure· August 2025

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Defining genetic diversity of rhesus macaque Fcγ receptors with long-read RNA sequencing.
Haleigh E Conley, Max M He, David Easterhoff, Hélène Fradin Kirshner, Sarah L Cocklin

Front Immunol· January 2024

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Multivariate analysis of FcR-mediated NK cell functions identifies unique clustering among humans and rhesus macaques.
Marina Tuyishime, Rachel L Spreng, Brady Hueber, Junsuke Nohara, Derrick Goodman, David Easterhoff

Front Immunol· December 2023

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Viral vector delivered immunogen focuses HIV-1 antibody specificity and increases durability of the circulating antibody recall response.
LaTonya D Williams, Xiaoying Shen, Sheetal S Sawant, Siriwat Akapirat, Lindsay C Dahora, David Easterhoff

PLoS Pathog· May 2023

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B cells expressing IgM B cell receptors of HIV-1 neutralizing antibodies discriminate antigen affinities by sensing binding association rates.
Md Alamgir Hossain, Kara Anasti, Brian Watts, Kenneth Cronin, Ronald Derking, David Easterhoff

Cell Rep· June 2022

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Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s.
William D Tolbert, Dung N Nguyen, Marina Tuyishime, Andrew R Crowley, Yaozong Chen, David Easterhoff

Front Immunol· February 2022

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Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques.
Justin Pollara, Matthew Zirui Tay, R Whitney Edwards, Derrick Goodman, Andrew R Crowley, David Easterhoff

Front Immunol· October 2021

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Erratum for Tolbert et al., "Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial".
William D Tolbert, Verna Van, Rebekah Sherburn, Marina Tuyishime, Fang Yan, David Easterhoff

mBio· April 2021

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Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
William D Tolbert, Verna Van, Rebekah Sherburn, Marina Tuyishime, Fang Yan, David Easterhoff

mBio· June 2020

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Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.
David Easterhoff, Justin Pollara, Kan Luo, William D Tolbert, Brianna Young

J Virol· January 2020

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HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
David Easterhoff, Justin Pollara, Kan Luo, Benjamin Janus, Neelakshi Gohain

JCI Insight· January 2020

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Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Kevin O Saunders, Kevin Wiehe, Ming Tian, Priyamvada Acharya, Todd Bradley, David Easterhoff

Science· December 2019

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Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.
Mattia Bonsignori, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam

Immunity· December 2018

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Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.
Kevin Wiehe, Todd Bradley, R Ryan Meyerhoff, Connor Hart, Wilton B Williams, David Easterhoff

Cell Host Microbe· June 2018

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Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates.
Shilei Ding, Myriam M Verly, Amy Princiotto, Bruno Melillo, Anthony M Moody, David Easterhoff

AIDS Res Hum Retroviruses· May 2017

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Lessons learned from human HIV vaccine trials.
Justin Pollara, David Easterhoff, Genevieve G Fouda

Curr Opin HIV AIDS· May 2017

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Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.
David Easterhoff, M Anthony Moody, Daniela Fera, Hao Cheng, Margaret Ackerman

PLoS Pathog· February 2017

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Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques.
Kan Luo, Hua-Xin Liao, Ruijun Zhang, David Easterhoff, Kevin Wiehe

JCI Insight· December 2016

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Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds.
Navid Madani, Amy M Princiotto, David Easterhoff, Todd Bradley, Kan Luo

J Virol· May 2016

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Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.
Kevin Wiehe, David Easterhoff, Kan Luo, Nathan I Nicely, Todd Bradley

Immunity· December 2014

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Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques.
M Anthony Moody, Sampa Santra, Nathan A Vandergrift, Laura L Sutherland, Thaddeus C Gurley, David Easterhoff

J Virol· March 2014

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Fluorescence detection of cationic amyloid fibrils in human semen.
David Easterhoff, John T M DiMaio, Wathsala Liyanage, Chi-Wen Lo, Woori Bae

Bioorg Med Chem Lett· September 2013

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Semen-derived enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against vaginal infection by a sexually transmitted bacterial pathogen.
David Easterhoff, Fernando Ontiveros, Lauren R Brooks, Yoel Kim, Brittany Ross

Antimicrob Agents Chemother· June 2013

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Advances in HIV microbicide development.
Joanna S Olsen, David Easterhoff, Stephen Dewhurst

Future Med Chem· December 2011

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Enhancement of HIV-1 infectivity by simple, self-assembling modular peptides.
David Easterhoff, John T M DiMaio, Todd M Doran, Stephen Dewhurst, Bradley L Nilsson

Biophys J· March 2011

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