Publications by authors named "Martin Handfield"

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Intranasal immunization with a proteosome-adjuvanted SARS-CoV-2 spike protein-based vaccine is immunogenic and efficacious in mice and hamsters.
Felicity C Stark, Bassel Akache, Lise Deschatelets, Anh Tran, Matthew Stuible, Martin Handfield

Sci Rep· June 2022

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Lipid II Binding and Transmembrane Properties of Various Antimicrobial Lanthipeptides.
Rudramani Pokhrel, Nisha Bhattarai, Prabin Baral, Bernard S Gerstman, Jae H Park, Martin Handfield

J Chem Theory Comput· January 2022

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Complete synthesis of the bicyclic ring of a mutacin analog with orthogonally protected lanthionine via solid-phase intracyclization.
Kostyantyn Kirichenko, Jeffrey D Hillman, Martin Handfield, Jae H Park

J Pept Sci· November 2019

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Preclinical evaluation of the maximum tolerated dose and toxicokinetics of enteric-coated lantibiotic OG253 capsules.
N V Rajeshkumar, Johan A Kers, Scott Moncrief, Anthony W Defusco, Jae H Park, Martin Handfield

Toxicol Appl Pharmacol· July 2019

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Molecular mechanisms of pore formation and membrane disruption by the antimicrobial lantibiotic peptide Mutacin 1140.
Rudramani Pokhrel, Nisha Bhattarai, Prabin Baral, Bernard S Gerstman, Jae H Park, Martin Handfield

Phys Chem Chem Phys· June 2019

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Pharmacological, Toxicological, and Dose Range Assessment of OG716, a Novel Lantibiotic for the Treatment of -Associated Infection.
Mark E Pulse, William J Weiss, Johan A Kers, Anthony W DeFusco, Jae H Park, Martin Handfield

Antimicrob Agents Chemother· April 2019

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Blueprints for the rational design of therapeutic mutacin 1140 variants.
Johan A Kers, R Eryl Sharp, Sheela Muley, Melissa Mayo, Jeffrey Colbeck, Martin Handfield

Chem Biol Drug Des· December 2018

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OG716: Designing a fit-for-purpose lantibiotic for the treatment of Clostridium difficile infections.
Johan A Kers, Anthony W DeFusco, Jae H Park, Jin Xu, Mark E Pulse, Martin Handfield

PLoS One· November 2018

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Mutacin 1140 Lantibiotic Variants Are Efficacious Against Infection.
Johan A Kers, Robert E Sharp, Anthony W Defusco, Jae H Park, Jin Xu, Martin Handfield

Front Microbiol· March 2018

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Identification of genes expressed in cultures of E. coli lysogens carrying the Shiga toxin-encoding prophage Φ24B.
Laura M Riley, Marta Veses-Garcia, Jeffrey D Hillman, Martin Handfield, Alan J McCarthy

BMC Microbiol· March 2012

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Use of in vivo-induced antigen technology (IVIAT) to identify virulence factors of Porphyromonas gingivalis.
Shannon M Wallet, Jin Chung, Martin Handfield

Methods Mol Biol· December 2010

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Identification of Leishmania proteins preferentially released in infected cells using change mediated antigen technology (CMAT).
Peter E Kima, J Alfredo Bonilla, Eumin Cho, Blaise Ndjamen, Johnathan Canton, Martin Handfield

PLoS Negl Trop Dis· October 2010

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Role of the ATM-checkpoint kinase 2 pathway in CDT-mediated apoptosis of gingival epithelial cells.
Mounia Alaoui-El-Azher, Jeffrey J Mans, Henry V Baker, Casey Chen, Ann Progulske-Fox, Martin Handfield

PLoS One· July 2010

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Subgingival bacterial colonization profiles correlate with gingival tissue gene expression.
Panos N Papapanou, Jan H Behle, Moritz Kebschull, Romanita Celenti, Dana L Wolf, Martin Handfield

BMC Microbiol· October 2009

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The degree of microbiome complexity influences the epithelial response to infection.
Jeffrey J Mans, Kate von Lackum, Cassandra Dorsey, Shaun Willis, Shannon M Wallet, Martin Handfield

BMC Genomics· August 2009

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Biomarkers for infants at risk for necrotizing enterocolitis: clues to prevention?
Christopher Young, Renu Sharma, Martin Handfield, Volker Mai, Josef Neu

Pediatr Res· May 2009

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Transcriptomes in healthy and diseased gingival tissues.
Ryan T Demmer, Jan H Behle, Dana L Wolf, Martin Handfield, Moritz Kebschull

J Periodontol· November 2008

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Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production.
Yoshiaki Hasegawa, Gena D Tribble, Henry V Baker, Jeffrey J Mans, Martin Handfield

Infect Immun· June 2008

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Application of in vivo induced antigen technology (IVIAT) to Bacillus anthracis.
Sean M Rollins, Amanda Peppercorn, John S Young, Melissa Drysdale, Andrea Baresch, Martin Handfield

PLoS One· March 2008

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Identification of Tannerella forsythia antigens specifically expressed in patients with periodontal disease.
Ji Yeon Yoo, Hyeong Chan Kim, Weidong Zhu, Seon-Mi Kim, Mojgan Sabet, Martin Handfield

FEMS Microbiol Lett· October 2007

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Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalis.
Song Mao, Yoonsuk Park, Yoshiaki Hasegawa, Gena D Tribble, Chlöe E James, Martin Handfield

Cell Microbiol· August 2007

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Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species.
Yoshiaki Hasegawa, Jeffrey J Mans, Song Mao, M Cecilia Lopez, Henry V Baker, Martin Handfield

Infect Immun· May 2007

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Microarray analysis of human epithelial cell responses to bacterial interaction.
Jeffrey J Mans, Richard J Lamont, Martin Handfield

Infect Disord Drug Targets· September 2006

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In vivo induced antigen technology (IVIAT) and change mediated antigen technology (CMAT).
Martin Handfield, Jeffrey D Hillman

Infect Disord Drug Targets· September 2006

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Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi.
Jason B Harris, Andrea Baresch-Bernal, Sean M Rollins, Ashfaqul Alam, Regina C LaRocque, Martin Handfield

Infect Immun· September 2006

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