Publications by authors named "Martin Jutras"

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Metabolite profiling in human and mouse liver microsomes of the aminosteroid RM-581, a new orally active anticancer agent.
Donald Poirier, Martin Jutras, René Maltais, Jenny Roy, Maude Fleury

Bioorg Chem· October 2025

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A Study Of the effect of Sex on drug dosing, concentrations, and pharmacogenomics in the Montreal Heart Institute Hospital Cohort (SOS-PGx): methodology and research progress.
Marc-Olivier Pilon, Jessica Hindi, Isabelle St-Jean, Martin Jutras, Maxime Meloche Brouillette

Eur J Clin Pharmacol· February 2025

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A Genome-Wide Association Study of Oxypurinol Concentrations in Patients Treated with Allopurinol.
Maxime Meloche, Marc-Olivier Pilon, Sylvie Provost, Grégoire Leclair, Essaïd Oussaïd, Martin Jutras

J Pers Med· June 2024

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Impact of amiodarone use on metoprolol concentrations, α-OH-metoprolol concentrations, metoprolol dosing and heart rate: A cross-sectional study.
Sabrina Robert, Marc-Olivier Pilon, Essaïd Oussaïd, Maxime Meloche, Grégoire Leclair, Martin Jutras

Pharmacol Res Perspect· October 2023

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Transfer of Mexiletine into Breast Milk: A Case Report.
Anaëlle Monfort, Caroline Morin, Martin Jutras, Stéphane Charest, Grégoire Leclair

Breastfeed Med· June 2023

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Pharmacogenomic markers of metoprolol and α-OH-metoprolol concentrations: a genome-wide association study.
Jean Laverdière, Maxime Meloche, Sylvie Provost, Grégoire Leclair, Essaïd Oussaïd, Martin Jutras

Pharmacogenomics· June 2023

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Females present higher dose-adjusted drug concentrations of metoprolol and allopurinol/oxypurinol than males.
Jessica Hindi, Marc-Olivier Pilon, Maxime Meloche, Grégoire Leclair, Essaïd Oussaïd, Martin Jutras

Clin Transl Sci· May 2023

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An association study of ABCG2 rs2231142 on the concentrations of allopurinol and its metabolites.
Marc-Olivier Pilon, Grégoire Leclair, Essaïd Oussaïd, Isabelle St-Jean, Martin Jutras

Clin Transl Sci· August 2022

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Evaluation of uptake of the cytostatic methotrexate in Elliptio complanata mussels by LC-MS/MS.
Sylvie Poirier Larabie, Martin Jutras, Grégoire Leclair, Isabelle St-Jean, Christine Kleinert

Environ Sci Pollut Res Int· June 2022

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Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof-of-concept study.
Maxime Meloche, Grégoire Leclair, Martin Jutras, Essaïd Oussaïd, Marie-Josée Gaulin

Clin Transl Sci· April 2022

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Simultaneous quantification of 19 analytes in breast milk by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Anaëlle Monfort, Martin Jutras, Brigitte Martin, Isabelle Boucoiran, Ema Ferreira

J Pharm Biomed Anal· September 2021

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Isocyanate derivatization coupled with phospholipid removal microelution-solid phase extraction for the simultaneous quantification of (S)-metoprolol and (S)-α-hydroxymetoprolol in human plasma with LC-MS/MS.
Maxime Meloche, Martin Jutras, Isabelle St-Jean, Simon de Denus, Grégoire Leclair

J Pharm Biomed Anal· September 2021

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Development and validation of a liquid chromatography coupled to tandem mass spectrometry method for the simultaneous quantification of five analgesics and sedatives, and six of their active metabolites in human plasma: Application to a clinical study on the determination of neurological death in the intensive care unit.
Martin Jutras, David Williamson, Michaël Chassé, Grégoire Leclair

J Pharm Biomed Anal· October 2020

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Spironolactone metabolite concentrations in decompensated heart failure: insights from the ATHENA-HF trial.
Simon de Denus, Grégoire Leclair, Marie-Pierre Dubé, Isabelle St-Jean, Yassamin Feroz Zada, Martin Jutras

Eur J Heart Fail· August 2020

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Erratum: Puscas, I.; et al. IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening. 2019, , 587.
Ina Puscas, Florian Bernard-Patrzynski, Martin Jutras, Marc-André Lécuyer, Lyne Bourbonnière

Pharmaceutics· June 2020

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IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening.
Ina Puscas, Florian Bernard-Patrzynski, Martin Jutras, Marc-André Lécuyer, Lyne Bourbonnière

Pharmaceutics· November 2019

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A comparison of the effects of selective and non-selective mineralocorticoid antagonism on glucose homeostasis of heart failure patients with glucose intolerance or type II diabetes: A randomized controlled double-blind trial.
Sandra Korol, Michel White, Eileen O'Meara, François Tournoux, Normand Racine, Martin Jutras

Am Heart J· October 2018

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Infant Exposure to Methylphenidate and Duloxetine During Lactation.
Laurence Collin-Lévesque, Yosra El-Ghaddaf, Madeleine Genest, Martin Jutras, Grégoire Leclair

Breastfeed Med· April 2018

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Spironolactone Metabolites in TOPCAT - New Insights into Regional Variation.
Simon de Denus, Eileen O'Meara, Akshay S Desai, Brian Claggett, Eldrin F Lewis, Martin Jutras

N Engl J Med· April 2017

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The liver partition coefficient-corrected inhibitory quotient and the pharmacokinetic-pharmacodynamic relationship of directly acting anti-hepatitis C virus agents in humans.
Jianmin Duan, Gordon Bolger, Michel Garneau, Ma'an Amad, Joëlle Batonga, Martin Jutras

Antimicrob Agents Chemother· October 2012

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Cross-species absorption, metabolism, distribution and pharmacokinetics of BI 201335, a potent HCV genotype 1 NS3/4A protease inhibitor.
Jianmin Duan, Chan-Loi Yong, Michel Garneau, Ma'an Amad, Gordon Bolger, Martin Jutras

Xenobiotica· February 2012

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