Publications by authors named "Martin Lochner"

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Investigation of the threonine metabolism of Echinococcus multilocularis: The threonine dehydrogenase as a potential drug target in alveolar echinococcosis.
Marc Kaethner, Pascal Zumstein, Joachim Müller, Matías Preza, Philipp Grossenbacher, Martin Lochner

Int J Parasitol Drugs Drug Resist· April 2025

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Identification of a binding site for small molecule inhibitors targeting human TRPM4.
Babatunde Ekundayo, Prakash Arullampalam, Christian E Gerber, Anne-Flore Hämmerli, Sabrina Guichard, Martin Lochner

Nat Commun· January 2025

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Mechanistic Insights into the Adenosine A1 Receptor's Positive Allosteric Modulation for Non-Opioid Analgesics.
Tal Weizmann, Abigail Pearce, Peter Griffin, Achille Schild, Maren Flaßhoff, Martin Lochner

Cells· December 2024

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Hypersensitive quantification of major astringency markers in food and wine by substoichiometric quenching of silicon-rhodamine conjugates.
Daniel Bátora, Ágnes Dienes-Nagy, Liming Zeng, Christian E Gerber, Jérôme P Fischer, Martin Lochner

Food Chem X· October 2024

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Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively Label Calcium Sensing Receptors , , and .
Daniel Bátora, Jérôme P Fischer, Reto M Kaderli, Máté Varga, Martin Lochner

ACS Pharmacol Transl Sci· May 2024

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CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells.
Sven Kappel, Korollus Melek, Daniela Ross-Kaschitza, Barbara Hauert, Christian E Gerber, Martin Lochner

Front Pharmacol· March 2024

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Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells.
Dominic Tscherrig, Rajesh Bhardwaj, Daniel Biner, Jan Dernič, Daniela Ross-Kaschitza, Martin Lochner

Cell Calcium· January 2024

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The uncertain advisor: trust, accuracy, and self-correction in an automated decision support system.
Martin Lochner, Daniel Smilek

Cogn Process· February 2023

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Targeting Ion Channel TRPM4.
Barbara Preti, Jean-Sébastien Rougier, Irida Papapostolou, Florian Bochen, Christian E Gerber, Martin Lochner

Chimia (Aarau)· December 2022

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Discovery and Structure-Activity Relationship Studies of Novel Adenosine A Receptor-Selective Agonists.
Barbara Preti, Anna Suchankova, Giuseppe Deganutti, Michele Leuenberger, Kerry Barkan, Martin Lochner

J Med Chem· November 2022

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Functional design of bacterial superoxide:quinone oxidoreductase.
Abbas Abou-Hamdan, Roman Mahler, Philipp Grossenbacher, Olivier Biner, Dan Sjöstrand, Martin Lochner

Biochim Biophys Acta Bioenerg· October 2022

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Bioorthogonal site-selective conjugation of fluorescent dyes to antibodies: method and potential applications.
Philipp Grossenbacher, Maria C Essers, Joël Moser, Simon A Singer, Stephanie Häusler, Martin Lochner

RSC Adv· October 2022

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Selective activation of Gαob by an adenosine A receptor agonist elicits analgesia without cardiorespiratory depression.
Mark J Wall, Emily Hill, Robert Huckstepp, Kerry Barkan, Giuseppe Deganutti, Martin Lochner

Nat Commun· July 2022

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Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors.
Prakash Arullampalam, Barbara Preti, Daniela Ross-Kaschitza, Martin Lochner, Jean-Sébastien Rougier

Front Pharmacol· July 2021

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Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters.
Michele Leuenberger, Stephanie Häusler, Vera Höhn, Adriana Euler, Bruno Stieger, Martin Lochner

J Pharmacol Exp Ther· June 2021

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Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor.
Giuseppe Deganutti, Kerry Barkan, Barbara Preti, Michele Leuenberger, Mark Wall, Martin Lochner

ACS Pharmacol Transl Sci· February 2021

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Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity.
Anthony Knight, Jennifer L Hemmings, Ian Winfield, Michele Leuenberger, Eugenia Frattini, Martin Lochner

J Med Chem· September 2020

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Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells.
Achille Schild, Rajesh Bhardwaj, Nicolas Wenger, Dominic Tscherrig, Palanivel Kandasamy, Martin Lochner

Int J Mol Sci· August 2020

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The Number and Position of Orai3 Units within Heteromeric Store-Operated Ca Channels Alter the Pharmacology of I.
Sven Kappel, Tatiana Kilch, Roland Baur, Martin Lochner, Christine Peinelt

Int J Mol Sci· April 2020

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A challenge finding P2X1 and P2X4 ligands.
Paul Beswick, Ben Wahab, Mark A Honey, Michael Paradowski, Ke Jiang, Martin Lochner

Neuropharmacology· October 2019

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Mapping the Orthosteric Binding Site of the Human 5-HT Receptor Using Photo-cross-linking Antagonists.
Thomas Jack, Michele Leuenberger, Marc-David Ruepp, Sanjeev Kumar V Vernekar, Andrew J Thompson, Martin Lochner

ACS Chem Neurosci· January 2019

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Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.
Lijo Cherian Ozhathil, Clémence Delalande, Beatrice Bianchi, Gabor Nemeth, Sven Kappel, Martin Lochner

Br J Pharmacol· June 2018

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The binding orientations of structurally-related ligands can differ; A cautionary note.
Marc-David Ruepp, Hao Wei, Michele Leuenberger, Martin Lochner, Andrew J Thompson

Neuropharmacology· June 2017

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The binding orientation of epibatidine at α7 nACh receptors.
Andrew J Thompson, Simon Metzger, Martin Lochner, Marc-David Ruepp

Neuropharmacology· April 2017

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Synthesis and Pharmacological Evaluation of [C]Granisetron and [F]Fluoropalonosetron as PET Probes for 5-HT Receptor Imaging.
Linjing Mu, Adrienne Müller Herde, Pascal M Rüefli, Filippo Sladojevich, Selena Milicevic Sephton, Martin Lochner

ACS Chem Neurosci· November 2016

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