Publications by authors named "Martin Schleef"

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Development of human targeted extracellular vesicles loaded with shRNA minicircles to prevent parkinsonian pathology.
Maria Izco, Carlos Sola, Martin Schleef, Marco Schmeer, María de Toro

Transl Neurodegener· May 2025

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Producing Plasmid DNA Template for Clinical Grade RNA Vaccine Manufacture.
Ram Shankar, Marco Schmeer, Martin Schleef

Methods Mol Biol· May 2024

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Targeted Extracellular Vesicle Gene Therapy for Modulating Alpha-Synuclein Expression in Gut and Spinal Cord.
Maria Izco, Martin Schleef, Marco Schmeer, Estefania Carlos, Guglielmo Verona

Pharmaceutics· April 2023

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Automated, scaled, transposon-based production of CAR T cells.
Dominik Lock, Razieh Monjezi, Caroline Brandes, Stephan Bates, Simon Lennartz, Martin Schleef

J Immunother Cancer· September 2022

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Minicircles for CAR T Cell Production by Sleeping Beauty Transposition: A Technological Overview.
Sabrina Prommersberger, Razieh Monjezi, Ram Shankar, Marco Schmeer, Michael Hudecek, Martin Schleef

Methods Mol Biol· June 2022

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Capillary Gel Electrophoresis (CGE) for Quality Control of Plasmid DNA in Gene Therapy: Quality Control of 20 Years Stored GMP-Grade Plasmid DNA.
Marco Schmeer, Martin Schleef, Ram Shankar, Dennis Kobelt, Wolfgang Walther

Methods Mol Biol· June 2022

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Correction to: Recombinant expression of Barnase in Escherichia coli and its application in plasmid purifcation.
Ram Shankar, Nina Schäfer, Marco Schmeer, Joe Max Risse, Karl Friehs, Martin Schleef

Microb Cell Fact· September 2021

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Recombinant expression of Barnase in Escherichia coli and its application in plasmid purification.
Ram Shankar, Nina Schäffer, Marco Schmeer, Joe Max Risse, Karl Friehs, Martin Schleef

Microb Cell Fact· August 2021

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Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology.
María Izco, Javier Blesa, Martin Schleef, Marco Schmeer, Riccardo Porcari

Mol Ther· December 2019

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Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.
Marta Holstein, Cristina Mesa-Nuñez, Csaba Miskey, Elena Almarza, Valentina Poletti, Martin Schleef

Mol Ther· April 2018

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Plasmid DNA Manufacturing for Indirect and Direct Clinical Applications.
Marco Schmeer, Tatjana Buchholz, Martin Schleef

Hum Gene Ther· October 2017

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Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells.
Michael Hudecek, Tea Gogishvili, Razieh Monjezi, Julia Wegner, Ram Shankar, Martin Schleef

Recent Results Cancer Res· June 2017

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Low-Dose Gene Therapy for Murine PKU Using Episomal Naked DNA Vectors Expressing PAH from Its Endogenous Liver Promoter.
Hiu Man Grisch-Chan, Andrea Schlegel, Tanja Scherer, Gabriella Allegri, Raphael Heidelberger, Martin Schleef

Mol Ther Nucleic Acids· June 2017

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Self-Complementary Adeno-Associated Virus Vectors Improve Transduction Efficiency of Corneal Endothelial Cells.
Anja K Gruenert, Marta Czugala, Chris Mueller, Marco Schmeer, Martin Schleef

PLoS One· August 2016

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Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design.
Reto P Bazzani, Ian A Pringle, Mary M Connolly, Lee A Davies, Stephanie G Sumner-Jones, Martin Schleef

Biomaterials· July 2016

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Production of Plasmid DNA as Pharmaceutical.
Marco Schmeer, Martin Schleef

Methods Mol Biol· March 2016

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Minicircle: Next Generation DNA Vectors for Vaccination.
Martin Schleef, R Schirmbeck, Michael Reiser, Marie-Louise Michel, Marco Schmeer

Methods Mol Biol· March 2016

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Cytoplasmic injection of murine zygotes with Sleeping Beauty transposon plasmids and minicircles results in the efficient generation of germline transgenic mice.
Wiebke Garrels, Thirumala R Talluri, Maren Ziegler, Ilka Most, Diego O Forcato, Martin Schleef

Biotechnol J· January 2016

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DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations.
Maria Schnödt, Marco Schmeer, Barbara Kracher, Christa Krüsemann, Laura Escalona Espinosa, Martin Schleef

Mol Ther Nucleic Acids· January 2016

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ColE1-Plasmid Production in Escherichia coli: Mathematical Simulation and Experimental Validation.
Inga Freudenau, Petra Lutter, Ruth Baier, Martin Schleef, Hanna Bednarz

Front Bioeng Biotechnol· September 2015

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Effect of the Compaction and the Size of DNA on the Nuclear Transfer Efficiency after Microinjection in Synchronized Cells.
Hidetaka Akita, Dai Kurihara, Marco Schmeer, Martin Schleef, Hideyoshi Harashima

Pharmaceutics· June 2015

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Pharmaceutical grade large-scale plasmid DNA manufacturing process.
Marco Schmeer, Martin Schleef

Methods Mol Biol· November 2014

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A seven-year storage report of good manufacturing practice-grade naked plasmid DNA: stability, topology, and in vitro/in vivo functional analysis.
Wolfgang Walther, Marco Schmeer, Dennis Kobelt, Ruth Baier, Alexander Harder, Martin Schleef

Hum Gene Ther Clin Dev· December 2013

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Dielectrophoresis based continuous-flow nano sorter: fast quality control of gene vaccines.
Martina Viefhues, Sonja Wegener, Anja Rischmüller, Martin Schleef, Dario Anselmetti

Lab Chip· August 2013

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Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.
Dennis Kobelt, Martin Schleef, Marco Schmeer, Jutta Aumann, Peter M Schlag

Mol Biotechnol· January 2013

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