Publications by authors named "Martin Trbusek"

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Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes.
Helena Olbertova, Karla Plevova, Sarka Pavlova, Jitka Malcikova, Jana Kotaskova, Martin Trbusek

BMC Cancer· February 2022

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Rituximab induces rapid blood repopulation by CLL cells mediated through their release from immune niches and complement exhaustion.
Marek Borsky, Viera Hrabcakova, Jitka Novotna, Yvona Brychtova, Michael Doubek, Martin Trbusek

Leuk Res· December 2021

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ATR-CHK1 pathway as a therapeutic target for acute and chronic leukemias.
Miroslav Boudny, Martin Trbusek

Cancer Treat Rev· August 2020

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PRIMA-1 cytotoxic effect correlates with p53 protein reduction in TP53-mutated chronic lymphocytic leukemia cells.
Zuzana Jaskova, Sarka Pavlova, Jitka Malcikova, Yvona Brychtova, Martin Trbusek

Leuk Res· February 2020

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Twenty Years of BRCA1 and BRCA2 Molecular Analysis at MMCI - Current Developments for the Classification of Variants.
Eva Machackova, Kathleen Claes, Miroslava Mikova, Jana Házová, Eva Hrabincová Sťahlová, Martin Trbusek

Klin Onkol· January 2020

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Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.
Miroslav Boudny, Jana Zemanova, Prashant Khirsariya, Marek Borsky, Jan Verner, Martin Trbusek

Haematologica· December 2019

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Detection and Functional Analysis of TP53 Mutations in CLL.
Sarka Pavlova, Jana Smardova, Nikola Tom, Martin Trbusek

Methods Mol Biol· June 2019

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ATM and TP53 mutations show mutual exclusivity but distinct clinical impact in mantle cell lymphoma patients.
Andrea Mareckova, Jitka Malcikova, Nikola Tom, Karol Pal, Lenka Radova, Martin Trbusek

Leuk Lymphoma· June 2019

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Impact of gene mutations and chromosomal aberrations on progression-free survival in chronic lymphocytic leukemia patients treated with front-line chemoimmunotherapy: Clinical practice experience.
Michaela Spunarova, Nikola Tom, Sarka Pavlova, Marek Mraz, Yvona Brychtova, Martin Trbusek

Leuk Res· June 2019

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MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells.
Katerina Cerna, Jan Oppelt, Vaclav Chochola, Katerina Musilova, Vaclav Seda, Martin Trbusek

Leukemia· February 2019

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Activation-induced deaminase and its splice variants associate with trisomy 12 in chronic lymphocytic leukemia.
Kristina Zaprazna, Kamila Reblova, Veronika Svobodova, Lenka Radova, Vojtech Bystry, Martin Trbusek

Ann Hematol· February 2019

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downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels.
Katerina Musilova, Jan Devan, Katerina Cerna, Vaclav Seda, Gabriela Pavlasova, Martin Trbusek

Blood· November 2018

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Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2 allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11.
Annelot Baert, Eva Machackova, Ilse Coene, Carol Cremin, Kristin Turner, Martin Trbusek

Hum Mutat· April 2018

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Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients.
Barbara Kantorova, Jitka Malcikova, Kamila Brazdilova, Marek Borsky, Karla Plevova, Martin Trbusek

Br J Haematol· September 2017

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NOD/SCID IL2Rγ-null mouse xenograft model of human p53-mutated chronic lymphocytic leukemia and ATM-mutated mantle cell lymphoma using permanent cell lines.
Jan Verner, Martin Trbusek, Jana Chovancova, Zuzana Jaskova, Mojmir Moulis

Leuk Lymphoma· September 2016

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ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres.
Veronika Navrkalova, Emma Young, Panagiotis Baliakas, Lenka Radova, Lesley-Ann Sutton, Martin Trbusek

Haematologica· September 2016

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Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis.
Gabriela Pavlasova, Marek Borsky, Vaclav Seda, Katerina Cerna, Jitka Osickova, Martin Trbusek

Blood· September 2016

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Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.
Jana Zemanova, Ondrej Hylse, Jana Collakova, Pavel Vesely, Alexandra Oltova, Martin Trbusek

Oncotarget· September 2016

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TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods.
Barbara Kantorova, Jitka Malcikova, Jana Smardova, Sarka Pavlova, Martin Trbusek

Tumour Biol· May 2015

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Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study.
Michael Doubek, Yvona Brychtova, Anna Panovska, Ludmila Sebejova, Olga Stehlikova, Martin Trbusek

Am J Hematol· May 2015

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Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting.
Lesley-Ann Sutton, Viktor Ljungström, Larry Mansouri, Emma Young, Diego Cortese, Martin Trbusek

Haematologica· March 2015

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Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays; an ERIC-wide approach.
G Doreen Te Raa, Jitka Malčiková, Marek Mraz, Martin Trbusek, Magali Le Garff-Tavernier

Br J Haematol· November 2014

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Distinct in vitro sensitivity of p53-mutated and ATM-mutated chronic lymphocytic leukemia cells to ofatumumab and rituximab.
Ludmila Sebejova, Marek Borsky, Zuzana Jaskova, David Potesil, Veronika Navrkalova, Martin Trbusek

Exp Hematol· October 2014

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The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors.
Jitka Malcikova, Evangelia Stalika, Zadie Davis, Karla Plevova, Martin Trbusek

Br J Haematol· August 2014

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TP53 aberrations in chronic lymphocytic leukemia.
Martin Trbusek, Jitka Malcikova

Adv Exp Med Biol· February 2014

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